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Aliri

Aliri is listed as a mid sized business research supplier in the Scientist.com network, with 4 sites in 2 countries.

Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 4

Countries 2

Type of company: Mid sized business

Antibodies

Immunodetection Use antibodies to identify a protein or antigen.

Bioimaging

Bioimaging Visualize biological process non-invasively in real time.
Electron Microscopy Examine the fine structures of molecules, cells and tissues with sub-nanometer resolution.
Luminescence Imaging Monitor biological processes and pathologies using reporter proteins such as firefly and Renilla luciferase.
Mass Spectrometry Imaging Visualize the spatial distribution of molecules, as biomarkers, metabolites, peptides or proteins by their molecular masses
Medical Imaging Visualize and analyze internal structures in animal models or patients.
Microscopy Use microscopy to analyze surfaces of biological materials and to develop 3D images of biological structures.

Biomarkers

Anatomic Pathology Do macroscopic, microscopic, biochemical, immunologic and molecular examination of organs and tissues.
Biomarker Analytical Validation Assess and optimize the characteristics of a candidate biomarker to ensure reproducibility and consistency.
Biomarker Discovery Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.
Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
Cell Membrane Lipidomics Study the pathways and networks of membrane lipids.
Complete Metabolic Panel Testing Detect electrolyte or glucose imbalance to identify or monitor related disorders.

Show all 27 in Biomarkers 21 more

Diagnostic Biomarkers Discovery Identify candidate biomarkers indicative of the presence of a disorder.
Digital Pathology Acquire, manage and interpret pathology information generated from a digital image of a slide preparation of cells or tissue.
Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
Hematoxylin & Eosin (H&E) Staining Visualize microscopic structures in cells or tissues.
Histopathology Evaluate slide preparation of cells or tissues for abnormal features.
Immunohistochemistry Examine the toxic effects of pre-clinical compounds in small animal and patient histological samples.
Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
In Vivo Apoptosis Detection Visualize and quantify apoptosis in real time.
Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Metabolomics Biomarker Discovery Identify and quantitate metabolite biomarkers in blood, urine, CSF and bodily fluids.
Multi-Omics Study Use an integrated multi-omics study to understand a disease mechanism.
Paraffin-based Histology Perform sectioning and histological analysis of wax-embedded samples.
Peptide Bioanalysis Analyze the structure of Peptides.
Pharmacodynamic Biomarkers Discovery Identify candidate biomarkers indicative of the therapeutic outcome of a drug-target interaction.
Predictive Biomarkers Discovery Identify candidate biomarkers suggestive of a response to a treatment.
Prognostic Biomarkers Discovery Identify candidate biomarkers representative of disease progression without treatment.
Protein Bioanalysis Quantitative measurement of xenobiotics (drugs and their metabolites, and biological molecules in unnatural locations or concentrations) and Proteins in biological systems
Single Cell Transcriptome Sequencing Detect distinct, rare or abnomal cell types in a heterogenous population.
Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Special Stainings Use a variety of techniques for the selective visualization of specific tissue or cell types.
Whole Transcriptome Amplification Amplify total RNA from a single cell.

Show all 102 services 89 more

Cell Culture and Characterization

Cell and Tissue Histology Prepare and stain frozen, fixed and embedded (FFPE) tissue samples.
Cryo-based Histology Perform sectioning and histological analysis of frozen non-fixed samples.
H & E Services For requesting services related to H&E Services
Histology Examine by microscopy the anatomy of cells and tissues of clinical patients and animal models.
Single Cell Services Request services to perform genomics, transcriptomics, proteomics, metabolomics and cell–cell interactions at the single cell level
Trichrome Staining Use a variety of techniques for the selective visualization of muscle, collagen fibers, fibrin and erythrocytes.

Chemical and Compound Analysis

Atomic Force Microscopy Use atomic force microscopy to reveal information about the atomic topography and mechanical properties of a sample.
GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) Analysis Detect metals and several non-metals at concentrations as low as one part in 1015 (part per quadrillion, ppq) on non-interfered low-background isotopes.
MALDI-TOF Analysis Use mass spectrometry technique to analyze compound, biomolecules and large organic molecules.
Non GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.

Show all 9 in Chemical and Compound Analysis 3 more

Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Protein Separation and Detection Separate proteins based on properties such as solubility, adsorption or size differences.
Sample Bioanalysis Determination of concentration of an analyte in biological sample.

Chemical and Compound Testing

Clinical Pathology Diagnose disease based on the laboratory analysis of bodily fluids, such as blood, urine and tissues.

Chemistry, Manufacturing and Controls (CMC)

Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services

Clinical Trials

Bioequivalence Studies Assess the expected biological equivalence of two proprietary preparations of a drug.
Pharmacokinetic Studies Design a study that observes the time course of drug absorption, distribution, metabolism, and excretion, as means to test the safety and effective therapeutic management of drugs in an individual patient.

Data Science/Bioinformatics

Clinical Biomarker Analysis An approach to finding markers that change in response to a drug or that identify a group that responds favorably to a specific therapy. These can be omics, molecular, histologic, radiologic, etc.
Clinical Companion Diagnostics Analysis The process of finding patients who are likely to respond positively to a drug and designing a diagnostic tool to identify this group of patients before or with a therapy.
Clinical Machine Learning/AI Complex analytical approaches to find patterns and make predictions in drug discovery projects
Clinical Responder Analysis, Patient Stratification The process of identifying patients that are more likely to respond positively to a drug.
Clinical Trial Integration Analysis The process of combining data from multiple clinical trials to understand categories of drugs and drug behavior in a more global way.
Discovery Bioinformatics Different analytical approaches that make, store, and analyze complex biological data.

Show all 12 in Data Science/Bioinformatics 6 more

Discovery Biomarker Analytics An approach to finding markers that change in response to a drug or that identify a group that responds favorably to a specific therapy. These can be omics, molecular, histologic, radiologic, etc.
Discovery Machine Learning/AI Complex analytical approaches to find patterns and make predictions in drug discovery projects.
Discovery Omics Analytics A process to analyze various omics data (genomics, transcriptomics, proteomics, metabolomics, etc.) This can include the integration of different omics data. Helps to better understand the molecular environment...
Discovery Statistical and Mathematical Modeling Use mathematical variables and equations to establish relationships between data.
Translational Biomarker Discovery An approach to finding markers that change in response to a drug or that identify a group that responds favorably to a specific therapy. These can be omics, molecular, histologic, radiologic, etc.
Translational Data Science and Modeling A process that helps make sense of your translational data

Discovery Chemistry

Time of Flight Mass Cytometry (CyTOF™) Detect and quantify up to 34 different proteins simultaneously on a single-cell level.

DNA & RNA

Expression Profiling Measure the the expression of thousands of genes at once to create a global picture of cellular function.
NGS: Next Generation Sequencing Sequence millions of template DNA molecules in parallel.
RNA Interference Use small sequences of RNA that correspond to the targeted gene product to inhibit mRNA translation.
RNA Profiling Quantify the expression levels of mRNA transcripts, enabling the determination of gene expression patterns.
Single Cell RNA Sequencing Quantify mRNA variants in a single cell.
Target Gene Expression Measure expression of a target gene at the protein, RNA and DNA level.

Show all 7 in DNA & RNA 1 more

Tissue Microarray Screen large numbers of tissues for the presence or absence of specific molecular markers.

General in vivo Toxicology

Single Maximum Tolerated Dose (MTD) Mouse Study Use mouse models to determine the MTD of a drug candidate by a single administration in a 7 day period.
Single Maximum Tolerated Dose (MTD) Rat Study Use rat models to determine the MTD of a drug candidate by a single administration in a 7 day period.

General Marketing

Database Management Software Facilitate the collection, tracking and processing of biological facts, statistics and observations.

In Vitro ADME

Compound Distribution Determine the metabolic fate of a drug candidate in tissue and organs of diseased and normal animal models.
Drug Distribution Studies Determine the metabolic fate of compounds within tissues, organs and plasma.
Metabolite Identification and Profiling Estimate drug candidate metabolites after administration of drug to an animal or human subject.
Metabolite Quantification Quantify drug metabolites formed after drug administration to an animal model or patient.
Metabolite Structural Elucidation Use analytical tools to characterize metabolite structure.

In Vitro Assays

Assay Development Construct or create new assays or modify existing ones.
Lipid Detection Use in vitro methods to identify lipid droplets and any associated proteins.
Pathway Mapping Define mechanisms of action by analyzing protein pathways affected by drug treatment.

In Vitro Pharmacology

Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.

In Vivo Pharmacokinetics

In Vivo PK Consulting Expert advice on pharmacokinetics and how specific drugs affect the body to determine function, effectiveness, dosage size, etc…
Mass Balance Elucidate excretory pathways and organ distribution of a parent drug and metabolites
Pharmacokinetic (PK) Screening Measure the absorption, distribution, metabolism and excretion of a compound.
Pharmacokinetic (PK) Screening - Minipig Run pharmacokinetic studies in minipigs that measure a drug’s absorption, distribution, metabolism and excretion.
Rat Efficacy Combination Use rat models to determine the anti-cancer efficacy and potential synergy of a drug candidate with a standard drug treatment.
Rat Efficacy Monotherapy Use rat models to determine the anti-cancer efficacy of a drug candidate compared to a positive control.

Show all 8 in In Vivo Pharmacokinetics 2 more

Repetitive Maximum Tolerated Dose (MTD) Mouse Study Use mouse models to determine the MTD of a drug candidate by repetitive administrations for 7 days.
Repetitive Maximum Tolerated Dose (MTD) Rat Study Use rat models to determine the MTD of a drug candidate by repetitive administrations for 7 days.

Protein Sciences

Mammalian Expression Express high yields of recombinant proteins, antibodies, virus, viral-subunit proteins and gene-therapy vectors.
Protein Expression Produce recombinant proteins in prokaryotic or eukaryotic systems.
Protein Identification Uncover or confirm the identity of a protein.
Proteomics Do large-scale experimental analysis of proteins focused on understanding structure and function.
Quantitative MS Quantify small and large molecules in the pg/ml range

Scientific Data Services

Machine Learning/ AI Predict and model an outcome (e.g. disease progression) based on input variables (i.e. features.)
Small RNA Gene Expression Quantify and analyze miRNA, piRNA, siRNA as well as other small nuclear RNAs from small-RNA-seq raw input data sets.
Software Tools Software tool for statistical analysis, data mining, genome annotation or NGS data analysis.

Other services

New Request

France Loos 2 sites
United States Colorado Springs, Salt Lake City 2 sites

Professional associations: AAPS, MassBio
Website: www.aliribio.com

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