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University of Massachusetts Medical School - Mouse Phenotyping/Metabolism Core
University of Massachusetts Medical School - Mouse Phenotyping/Metabolism Core is listed as an academic core research supplier in the Scientist.com network, with 1 site in 1 country.
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Logo UMasswebteam, via Wikimedia Commons, CC BY-SA 4.0. Shown to identify the organization; it may be a registered trademark.
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Academic core
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Where it operates
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United States 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
The Metabolism Core conducts specialized and non-invasive metabolic experiments to measure insulin sensitivity, glucose/lipid/protein metabolism, pancreatic β-cell function, body composition and energy balance. Most experiments are performed under physiological state and in conscious mice. The Core services include: Hyperinsulinemic-euglycemic clamp to assess insulin action in conscious mice (method) Glucose, lipid and protein metabolism in individual organs using radioactive-labeled metabolites in conscious mice (method) Hyperglycemic clamp to assess insulin secretion and pancreatic β-cell...
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The Metabolism Core conducts specialized and non-invasive metabolic experiments to measure insulin sensitivity, glucose/lipid/protein metabolism, pancreatic β-cell function, body composition and energy balance. Most experiments are performed under physiological state and in conscious mice. The Core services include:
- Hyperinsulinemic-euglycemic clamp to assess insulin action in conscious mice (method)
Glucose, lipid and protein metabolism in individual organs using radioactive-labeled metabolites in conscious mice (method)
- Hyperglycemic clamp to assess insulin secretion and pancreatic β-cell function (method)
- Glucose and insulin tolerance tests (method)
- Survival surgery of jugular vein cannulation for in vivo experiments (method)
- Chronic and acute induction of obesity, insulin resistance and diabetes using high-fat diet, lipid infusion, streptozotocin injection and phloridzin treatment (method)
- Implementation of osmotic pumps or subcutaneous injection for chronic administration of drugs (drug trial study) (method)
- Non-invasive measurement of food/water intake, energy expenditure, respiratory exchange ratio and physical activity using the metabolic cages (method)
- Non-invasive assessment of whole body and tissue composition of fat/lean/water mass using1H-MRS (method)
- Application of in-house cage wheel for exercise studies
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