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Alcyomics
Alcyomics is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country and 1 service area.
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Sites
1
Countries
1
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Antibodies
- Immunodetection Use antibodies to identify a protein or antigen.
Biomarkers
- Cell Migration Assays Measure chemotaxis, haptotaxis, transmigration and wound-healing.
- Chemotaxis Assays Investigate the in vivo or in vitro movement of cells towards or away from a chemotactic agent.
- Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
- Hematoxylin & Eosin (H&E) Staining Visualize microscopic structures in cells or tissues.
- Immunohistochemistry Examine the toxic effects of pre-clinical compounds in small animal and patient histological samples.
- Paraffin-based Histology Perform sectioning and histological analysis of wax-embedded samples.
Cell Culture and Characterization
- 3D Cell Culture Use a scaffold-based or scaffold-free format to grow three dimensional cell and tissue structures.
- Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
- Cell and Tissue Histology Prepare and stain frozen, fixed and embedded (FFPE) tissue samples.
- Cell Culture Culture primary or immortalized cell lines.
- Cell Sorting The purpose of cell separation is to isolate a cell population from other cells in a biological sample.
- Cryo-based Histology Perform sectioning and histological analysis of frozen non-fixed samples.
Show all 11 in Cell Culture and Characterization
- Explant Culture Culture cells obtained from a part or parts of an in vivo structure.
- Histology Examine by microscopy the anatomy of cells and tissues of clinical patients and animal models.
- Mycobacterium Screening Detect and distinguish between mycobacterium strains and species.
- Organotypic Culture Co-culture different cells to enable in vitro growth of an in vivo tissue or organ equivalent.
- Trichrome Staining Use a variety of techniques for the selective visualization of muscle, collagen fibers, fibrin and erythrocytes.
Show all 61 services
Disease Models
- Atopic Dermatitis Models Measure therapeutic endpoints in animal models of atopic dermatitis.
DNA & RNA
- RNA Extraction Isolate total RNA or mRNA from cells or tissues
General in vivo Toxicology
- General Toxicology Use in vivo models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.
Human Biological Samples
- Biospecimen Finder Explore listings of Human Biological Samples from the suppliers on the scientist.com HBS database
- FRBESaHBS Request human biosamples including tissues, blood, serum, bone marrow, and tissue microarrays.
- HBS: Human Biological Samples Request human biosamples including tissues, blood, serum, bone marrow, tissue microarrays, etc.
- Human 3D cultures Provision of 3D culture of Human Primary Cells
- Human Cell Lysates For requesting human Cell lysates.
- Human Cell Products For requesting human cell by products like proteins, lysates, lysosomes etc
Show all 8 in Human Biological Samples
- Human Peripheral Blood Mononuclear Cells (PBMCs) Acquire fresh/frozen normal PBMCs based on patient demographics and history.
- Human Primary Cells Acquire fresh/frozen human primary cells based on patient demographics, disease stage, history and treatment. Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely”...
In Vitro ADME
- Cell Permeability and Absorbance Models Cell Permeability and Absorbance Model assay.
- Skin Permeability Use human skin models to determine transdermal delivery and percutaneous absorption of pre-clinical drugs.
In Vitro Assays
- 3D Cell Microscopy Assay Investigate cellular and subcellular events in three dimensional 3D cultures by using fluorescence microscopy.
- Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
- Apoptotic Cell Staining Detect apoptotic cells in culture.
- Assay Development Construct or create new assays or modify existing ones.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Cell Based Assays Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
Show all 14 in In Vitro Assays
- Cell Cycle Assays Measure cell cycle markers and the molecular events that control cell cycle progression.
- Cell Proliferation Measure cell number, cell viability and cell division.
- Hydroxyproline Assays Use biochemical, cell based or in vivo assays to quantify hydroxyproline or collagen in a sample.
- In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
- In Vitro Efficacy Test Use in vitro models to test the efficacy of your products.
- In Vitro Human Cell Assays Request in vitro human cells for assays
- Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
- Invasion Assays Monitor and quantify the ability of cultured cells to permeate real or artificial biological barriers.
In Vitro Pharmacology
- In Vitro Bone Models Measure osteoclast activity and bone formation in human or rat osteoclasts.
- In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
- In Vitro Neural Models Use cultured neurons, neuronal progenitor cells and stem cell differentiation to create cellular models of neurological disease.
In Vitro Toxicology
- Cytotoxicity Test for effects on cell viability and proliferation
- Cytotoxicity Testing Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.
- Epidermal Cell Toxicity Measure toxicity by quantifying the number of live/dead cells, cell membrane integrity and glutathione (GSH) levels.
Protein Sciences
- Cytokines Find recombinant cytokines or cytokine assays.
REACH Services
- In Vitro Skin Sensitization Determine whether a drug or cosmetic product may cause dermal sensitization.
- OECD 431: In Vitro Skin Corrosion: Human Skin Model Test The test described in this Test Guideline allows the identification of corrosive chemical substances and mixtures and it enables the identification of non-corrosive substances and mixtures when supported by a weight...
Safety Pharmacology
- Immunotoxicity Measure effects of drugs on immune function, allergic hypersensitization and autoimmune toxicity.
- Safety Pharmacology Assess the impact of a therapeutic for human use on vital organ systems before first-in-man drug testing.
Testing Services
- In Vitro Skin Models Measure skin model penetration and invasion, photosensitivity and toxicity.
- OECD 439: Skin Irritation Test (SIT) Reconstructed Human Epidermis Test (RhE) Method - An in vitro testing method designed to identify chemicals and/or mixtures capable of inducing moderate skin irritation.
- Skin Lightening Product Test Measure qualitative and quantitative changes in skin pigmentation under the influence of the test sample.
Other services
- Human Dendritic Cell (hDC) Model Test and validate the immune-modulating compounds in DC immune pathway models.
- New Request
Service areas:
Toxicology
Where it operates
Sites by country, with the cities in each.
-
United Kingdom 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Alcyomics offers cytokine assays, immunohistochemistry, and mRNA analysis services for immunogenicity testing.
- Website
- www.alcyomics.com
Work with Alcyomics on Scientist.com
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