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Babraham Institute Enterprise Limited

Babraham Institute Enterprise Limited is listed as an academic core research supplier in the Scientist.com network, with 7 sites in 1 country.

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Sites 7
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Academic core

Bioimaging

  • Bioimaging Visualize biological process non-invasively in real time.
  • Medical Imaging Visualize and analyze internal structures in animal models or patients.
  • Microscopy Use microscopy to analyze surfaces of biological materials and to develop 3D images of biological structures.
  • Scanning Electron Microscopy Examine the fine structures of molecules, cells and tissues with sub-nanometer resolution.
  • Super Resolution Microscopy Utilize fluorescence microscopy and super-resolution techniques including STED, SIM, SMLM, and/or STORM to directly observe living subcellular structures and activities.

Biomarkers

  • Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
  • Immunophenotyping Separate cell types based on their expression of biomarkers or based on their individual and unique expression patterns.
  • Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
  • Multi-Omics Study Use an integrated multi-omics study to understand a disease mechanism.
  • Propidium Iodide FACS Analysis Use DNA staining and flow cytometry to analyze the cell cycle and detect apoptosis or cell proliferation.
  • Single Cell Isolation Isolate single cells for subsequent single-cell analysis.
Show all 8 in Biomarkers 2 more
  • Single Cell Transcriptome Sequencing Detect distinct, rare or abnomal cell types in a heterogenous population.
  • Stem Cell Analysis Assess hematopoietic, neural and mesenchymal cell progenitor proliferation and differentiation.

Cell Culture and Characterization

  • Cell Sorting The purpose of cell separation is to isolate a cell population from other cells in a biological sample.
  • Isogenic Knockout iPSC Lines Mimic loss of function of genes associated with various diseases and disorders.
  • Signaling Pathways Find proteins, assays and custom reagents for the analysis of cell signaling pathways.
  • Single Cell DNA Sequencing Examine genetic variations in a single cell.
  • Single Cell Services Request services to perform genomics, transcriptomics, proteomics, metabolomics and cell–cell interactions at the single cell level
Show all 38 services 22 more

DNA & RNA

  • DNA Sequencing Determine the nucleotide sequence of DNA samples.
  • Genome Editing Use CRISPR, ZFN, TALEN or AAV gene targeting for targeted gene mutations and creation of transgenics.
  • Integrated Genomics Package Process an entire Genomics Pipeline Project including: Sample Preparation, Target Enrichment, NGS Instrumentation, and Data Analysis from our Bundle of Suppliers
  • Knockout/Knockin Cell Lines Develop Knockout/Knockin Cell Line.
  • Long Read Sequencing Long read sequencing is used in genomics to sequence long fragments of DNA, enabling the ability to span complex regions of the genome.
  • NGS: Next Generation Sequencing Sequence millions of template DNA molecules in parallel.
Show all 9 in DNA & RNA 3 more
  • shRNA Synthesis Design shRNA constructs that produce stable knockdown of the corresponding mRNA.
  • Single Cell ATAC Sequencing Single Cell Assay for Transposase-Accessible Chromatin Sequencing is a genomic technique used to study the accessibility of chromatin at the single-cell level.
  • Single Cell RNA Sequencing Quantify mRNA variants in a single cell.

Drug Development

  • Cellular Immunology Consulting Immunological activities of cells in experimental or clinical situations

In Vitro Assays

  • Annexin V Apoptosis Assay Detect and quantify apoptotic cells based on loss of membrane asymmetry.
  • Apoptotic Cell Staining Detect apoptotic cells in culture.
  • BrdU S-Phase Analysis Assess cell division or apoptosis by measuring thymidine-analog label incorporation during DNA replication.
  • Cytometric Bead Array (CBA) FACS Analysis Use flow cytometry and antibody-coated beads to simultaneously detect multiple target proteins.
  • PrimeFlow™ RNA Assay Reveal the unique kinetics of mRNA and protein in the same cell and identify expression differences as they change over time in response to stimulus.

Model Development

  • Knockin Mice Make targeted insertion of a gene of interest into a specific gene locus to create transgenic mice.
  • Knockout Mice Create transgenic mice that are genetically engineered to inactivate a gene or set of genes.
  • Transgenic Models Create animal models engineered for use in a specific therapeutic area.

Real World Evidence & Data

  • RWD - Genomics Genomic data collected from a patients with different diseases, can be derived from a range of sources.

Scientific Data Services

  • Genome Data Analysis Analyze genomic DNA, RNA and protein sequence data.

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • United Kingdom Cambridge 7 sites

Source: Scientist.com supplier network (site locations)

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Sources: Scientist.com supplier network.

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