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Research supplier
SYNthesis MedChem Pty
SYNthesis MedChem Pty is listed as a mid sized business research supplier in the Scientist.com network, with 4 sites in 3 countries and 1 service area.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Mid sized business
Chemical and Compound Analysis
- Chiral Separation Purify therapeutically active isomers of drug candidates.
- Compound Integrity Analyze the identity and purity of small molecule drug candidates.
- Melting Point Use melting point analysis to characterize compounds based on calorimetry and thermodynamic data.
- NMR Structure Determine molecular structure, identify chemical impurities and validate sample integrity.
- Optical Rotation Distinguish between optical isomers as well as between natural versus man-made compounds.
- Solution Nuclear Magnetic Resonance Identify molecular structure or impurities and assess product integrity of solution samples.
Chemistry, Manufacturing and Controls (CMC)
- Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
Discovery Chemistry
- Bioactive Research Tools Find bioactive peptides, bioactive lipids, bioactive materials like glass, paper, and polymers and nanotechnology.
- Building Blocks Find chemicals used for creating new compound chemotypes and HTS libraries.
- Compound Purchase Consulting Buy compounds, building blocks or compound libraries.
- Compound Synthesis Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
- Custom Building Blocks Find or synthesize mg to kg amounts of chemical building blocks, scaffolds and reactive intermediates.
- Custom Libraries Find or synthesize mg to kg amounts of target-specific and target-agnostic compounds for HTS and biological profiling.
Show all 18 in Discovery Chemistry
- Custom Synthesis Find or synthesize mg to kg amounts of target-specific and target agnostic compounds for HTS and biological screening.
- Hit to Lead (H2L) Evaluate, perform limited optimization and identify small molecule hits from high throughput screens.
- LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
- Lead Optimization Perform chemical structural changes to improve preclinical drug candidate.
- Method Development and Validation Develop and validate methods for synthesis and scale up of drug candidates.
- Natural Product Screening Screen large natural product collections for therapeutic activity.
- Pharmaceutical Research Chemicals Acquire chemicals that are prospective new drug entities.
- Stable Isotope Synthesis Label drug candidates with stable isotopes that simplify compound tracking and distribution studies.
- Structure Activity Relationship (SAR) Analyze the relationship between the structure of a compound and its biological activity.
- Structure Property Relationship (SPR) Determine the functionality of a compound through the analysis of it's structure.
- Target-Focused Compound Libraries Find activity-based libraries directed towards a protein or cell signaling target.
- UV and IR Profiling Analyze the integrity of a compound or large biomolecule.
Show all 27 services
Drug Development
- Medicinal Chemistry Consulting Apply chemistry training to the process of synthesizing new pharmaceuticals.
In Vitro ADME
- Reference Standards Find reference standards for assays, tests and services.
Service areas:
Where it operates
Sites by country, with the cities in each.
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China 2 sites
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Australia 1 site
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Hong Kong 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Founded as a customer-focused and innovation-driven contract research organisation (CRO), SYNthesis med chem provide pre-clinical research such as computational chemistry, medicinal chemistry and organic synthesis to biotechs and pharmaceutical industry worldwide. With our Head Office located in Melbourne, Australia, and our major laboratory facility in Suzhou (75000 square feet) and in Shanghai(15000 square feet), People’s Republic of China, we offer the best of both worlds; a Western-style management service, coupled with Chinese drive and productivity. Our marketing teams are working...
Show the full description
Founded as a customer-focused and innovation-driven contract research organisation (CRO), SYNthesis med chem provide pre-clinical research such as computational chemistry, medicinal chemistry and organic synthesis to biotechs and pharmaceutical industry worldwide. With our Head Office located in Melbourne, Australia, and our major laboratory facility in Suzhou (75000 square feet) and in Shanghai(15000 square feet), People’s Republic of China, we offer the best of both worlds; a Western-style management service, coupled with Chinese drive and productivity. Our marketing teams are working from UK (Cambridge), AU (Melbourne), China (Suzhou), and US (San Diego) offices.
SYNthesis is committed to help its partners to cut the cost and accelerate the drug discovery by providing efficient, high-quality and cost-effective discovery chemistry service. Our senior management team is made up of western-trained PhDs and Postdocs with rich experience in drug discovery, especially in medicinal chemistry and synthetic chemistry. Together the team has more than 300 publications and 35 granted patents.
SYNthesis is proud to have an experienced and very productive group of chemists working in a variety of areas including synthetic chemistry, medicinal chemistry, computational chemistry, process chemistry and analytical chemistry. We offer a range of flexible collaborative relationships with our partners, such as FTE-based service, Risk-sharing project-based service, contract synthesis and catalogue service. We have proven experience and expertise in in silico screening of libraries and then design of target molecules, synthesis of small focussed libraries, reference compounds and metabolites, design and synthesis of a wide range of heterocyclic scaffolds. We offer a full palette of early drug discovery focussed services; seamlessly integrated and well co-ordinated through timely project management.
In last three years we have worked very closely with our customers on the following areas:
• Design and synthesis of focused libraries for hit exploration;
• Design and synthesis of close analogues for lead optimisation;
• Scaling up preparation of key intermediates and final compounds (1-100g);
• Synthesis of literature compounds and their analogues;
• Synthesis of reported drug candidates, their metabolites and impurities;
• Route optimisation of synthetic routes;
• Design and execution of new synthetic routes to new molecules.
• Draft research proposal and patent application.
- Professional associations
- ACS
- Website
- www.synmedchem.com
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