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Research supplier
Sphaera Pharma
Sphaera Pharma is listed as a small business research supplier in the Scientist.com network, with 3 sites in 1 country.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
General in vivo Toxicology
- Single Maximum Tolerated Dose (MTD) Mouse Study Use mouse models to determine the MTD of a drug candidate by a single administration in a 7 day period.
- Single Maximum Tolerated Dose (MTD) Rat Study Use rat models to determine the MTD of a drug candidate by a single administration in a 7 day period.
In Vitro ADME
- Metabolic Stability in Microsomes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver microsomes.
In Vivo Pharmacokinetics
- Repetitive Maximum Tolerated Dose (MTD) Mouse Study Use mouse models to determine the MTD of a drug candidate by repetitive administrations for 7 days.
- Repetitive Maximum Tolerated Dose (MTD) Rat Study Use rat models to determine the MTD of a drug candidate by repetitive administrations for 7 days.
Model Development
- Sprague Dawley Rat Use a single animal species to create one or more disease models for cachexia.
Oncology Models
- Oncology Models Use model organisms to test the therapeutic efficacy of cancer drug candidates.
- Xenograft Models Measure therapeutic endpoints in cancer models using tumor cells transplanted from a donor of a different species.
Safety Pharmacology
- Safety Pharmacology Assess the impact of a therapeutic for human use on vital organ systems before first-in-man drug testing.
Other services
- Pfizer Sourcing Request Initiate a new request supported by a Pfizer Sourcing Group
Where it operates
Sites by country, with the cities in each.
-
India 3 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Sphaera Pharma, founded in 2008, offers integrated R&D services. We offer a unique service model exploiting our drug discovery and development experience to partner effectively and efficiently with our clients. Our approach to scientific challenges is based on the internal programs that we have advanced through the pre-clinical development stage. Sphaera has a dynamic leadership team with more than 7 years’ experience at the current facility. We follow a strong confidentiality protocol internally. All client data is shared on a ‘need to know’ basis only and is managed using Sphaera’s...
Show the full description
Sphaera Pharma, founded in 2008, offers integrated R&D services. We offer a unique service model exploiting our drug discovery and development experience to partner effectively and efficiently with our clients.
Our approach to scientific challenges is based on the internal programs that we have advanced through the pre-clinical development stage. Sphaera has a dynamic leadership team with more than 7 years’ experience at the current facility.
We follow a strong confidentiality protocol internally. All client data is shared on a ‘need to know’ basis only and is managed using Sphaera’s proprietary In-Reg® platform
Sphaera Pharma offers various biology services:
+In Vivo (Non-GLP):+
- Pharmacokinetics study;
- Route of administration- oral, iv, sc, ip;
- Mouse (Balb/c, nude mice); Rat - SD
- Dose tolerance check;
- Accumulation study;
- In vivo efficacy Study in nude mice using oncogenic cell lines (Xenograft)
- PK/ADME (Rats and mice);
- Screening Toxicology in rodents
+Downloads+
In Vivo Capabilities Brochure
- Website
- sphaerapharma.com
Work with Sphaera Pharma on Scientist.com
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