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CARE Research

CARE Research is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country and 3 service areas.

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Sites 2
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Small business

Biomarkers

  • Anatomic Pathology Do macroscopic, microscopic, biochemical, immunologic and molecular examination of organs and tissues.
  • Histopathology Evaluate slide preparation of cells or tissues for abnormal features.

Cell Culture and Characterization

  • Histology Examine by microscopy the anatomy of cells and tissues of clinical patients and animal models.

Chemical and Compound Testing

  • Nutritional Testing Analyze food safety, vendor specifications, foreign substance identification processes and nutritional labeling.

Clinical Trials

  • Bioequivalence Studies Assess the expected biological equivalence of two proprietary preparations of a drug.

Developmental and Reproductive Toxicology (DART)

  • Reproductive Toxicology Study adverse sexual function and fertility and examine teratogenicity of compounds.

Disease Models

  • Behavioral Testing Models Investigate sensory-motor and emotional functions, social behavior and day-night activity.
  • Cough Models Test the therapeutic efficacy of drug candidates in cough models.
  • Morris Water Maze Investigate spatial learning and memory in rodents.
  • Ob/ob Mouse Use a single animal species to create one or more disease models obesity and angiogenesis.
  • Obese Mice Use a single animal species to create one or more disease models for diet-induced obesity and type II diabetes.
  • Olfactory Testing Models Measure therapeutic endpoints in animal models of olfactory function.
Show all 83 services 71 more

Effectiveness

  • In Vitro Dose Determination Tests Determine the most appropriate effective drug dosage regimen(s) in vitro.
  • Laboratory Dose Determination Studies Compare the effectiveness of three non-zero therapeutic concentrations for various durations to a non-medicated control group, and a non-medicated uninfected control group.

General in vivo Toxicology

  • Carcinogenicity Study - Mouse Conduct a repeat dose, chronic carcinogenicity study in mice to determine the tendency of your compound to produce tumors.
  • Dose Range Finding Study - Dog /Canine Conduct a study to determine the dose range of your compound in dogs/canines.
  • Dose Range Finding Study - Mouse Conduct a study to determine the dose range of your compound in mice.
  • Dose Range Finding Study - Other Species Conduct a study to determine the dose range of your compound in other species.
  • Dose Range Finding Study - Rat Conduct a study to determine the dose range of your compound in rats.
  • General Toxicology Use in vivo models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.
Show all 16 in General in vivo Toxicology 10 more
  • Mammalian Toxicology Use toxicity testing models to carry out required FDA or REACH safety testing.
  • Oral Toxicology Use toxicity studies in animals to evaluate the oral toxicity of a drug candidate.
  • Repeat Dose Toxicity Study - Dog / Canine Conduct a repeat dose study in dogs to determine the toxicity and toxicokinetic behavior of your compound.
  • Repeat Dose Toxicity Study - Mouse Conduct a repeat dose study in mice to determine the toxicity and toxicokinetic behavior of your compound.
  • Repeat Dose Toxicity Study - Other Species Conduct a repeat dose study in other species to determine the toxicity and toxicokinetic behavior of your compound.
  • Repeat Dose Toxicity Study - Rat Conduct a repeat dose study in rats to determine the toxicity and toxicokinetic behavior of your compound.
  • Single Dose Acute Toxicity Study - Dog / Canine Conduct a single dose study in Dogs and Canines to determine the toxicokinetic behavior of your compound.
  • Single Dose Acute Toxicity Study - Mouse Conduct a single dose study in Mice and Murines to determine the toxicokinetic behavior of your compound.
  • Single Maximum Tolerated Dose (MTD) Mouse Study Use mouse models to determine the MTD of a drug candidate by a single administration in a 7 day period.
  • Single Maximum Tolerated Dose (MTD) Rat Study Use rat models to determine the MTD of a drug candidate by a single administration in a 7 day period.

In Vitro ADME

  • Blood Brain Barrier Measure movement of drugs from circulating blood to brain extracellular fluid.

In Vitro Assays

  • In Vitro Efficacy Test Use in vitro models to test the efficacy of your products.

In Vivo Pharmacokinetics

  • In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
  • Pharmacokinetic (PK) Screening - Mouse Run pharmacokinetic studies in mice that measure a drug's absorption, distribution, metabolism and excretion.
  • Pharmacokinetic (PK) Screening - Other Species Run pharmacokinetic studies in large animals that measure a drug's absorption, distribution, metabolism and excretion.
  • Pharmacokinetic (PK) Screening - Rat Run pharmacokinetic studies in rats that measure a drug's absorption, distribution, metabolism and excretion.
  • Rat Efficacy Combination Use rat models to determine the anti-cancer efficacy and potential synergy of a drug candidate with a standard drug treatment.
  • Repetitive Maximum Tolerated Dose (MTD) Mouse Study Use mouse models to determine the MTD of a drug candidate by repetitive administrations for 7 days.
Show all 7 in In Vivo Pharmacokinetics 1 more
  • Repetitive Maximum Tolerated Dose (MTD) Rat Study Use rat models to determine the MTD of a drug candidate by repetitive administrations for 7 days.

Model Development

  • Non-Human Primate Models Use a single animal species to create one or more disease models.
  • Pulmonary Hypertension Animal Model Study the pathology of pulmonary arterial hypertension (PAH) and investigate potential therapies.
  • Standard Models Create new animal disease models or modify existing models to study specific diseases, side-effects or symptoms.

Other Specialty Toxicology

  • Biosafety Testing Consulting Expert advice to conduct safe and responsible biological procedures and practices.
  • Microbial Testing Test samples for microorganisms, identify species, do bioburden analysis and measure endotoxin levels (LAL).
  • Raw Materials Testing Verify that raw materials are sterile and not contaminated by mycoplasma, virus or other microorganisms.
  • Tumorigenicity Testing Test tumor-forming properties of cell products.

Safety Pharmacology

  • Immunotoxicity Measure effects of drugs on immune function, allergic hypersensitization and autoimmune toxicity.

Specialty Dosing Routes

  • Dermal Toxicology Assess toxicity in rodent dermal testing models.
  • Intracameral Implant Toxicity and/or Toxicokinetic Study - Dog / Canine Conduct an intracameral implant toxicity study in dogs/canines to determine the toxicity and toxicokinetic behavior of your compound.
  • Intracameral Implant Toxicity and/or Toxicokinetic Study - Other Species Conduct an intracameral implant toxicity study in other species to determine the toxicity and toxicokinetic behavior of your compound.
  • Intracameral Implant Toxicity and/or Toxicokinetic Study - Rabbit, Pigmented (Dutch Belted, New Zealand Red) Conduct an intracameral implant toxicity study in pigmented rabbits to determine the toxicity and toxicokinetic behavior of your compound.
  • Intrathecal/Intraspinal Toxicology Conduct a study to determine the toxicity and toxicokinetic behavior of your compound when delivered via the intrathecal space.
  • Intravitreal Toxicity and/or Toxicokinetic Study - Dog / Canine Conduct an intravitreal ocular toxicity study in dogs/canines to determine the toxicity and toxicokinetic behavior of your compound.
Show all 34 in Specialty Dosing Routes 28 more
  • Intravitreal Toxicity and/or Toxicokinetic Study - Minipig Conduct an intravitreal ocular toxicity study in minipigs to determine the toxicity and toxicokinetic behavior of your compound.
  • Ophthalmologic Toxicology Measure toxicity by microscopy, vitrectomy, tonometry, electroretionography and corneal colorimetry.
  • Repeat Dose Intranasal Study - Dog / Canine Conduct a repeat dose intranasal study in dogs/canines to determine the toxicity and toxicokinetic behavior of your compound.
  • Repeat Dose Intranasal Study - Mouse Conduct a repeat dose intranasal study in mice to determine the toxicity and toxicokinetic behavior of your compound.
  • Repeat Dose Intranasal Study - Other Species Conduct a repeat dose intranasal study in other species to determine the toxicity and toxicokinetic behavior of your compound.
  • Repeat Dose Intranasal Study - Rat Conduct a repeat dose intranasal study in rats to determine the toxicity and toxicokinetic behavior of your compound.
  • Repeat Dose Intravenous Infusion Study - Dog / Canine Conduct a repeat dose intravenous infusion study in dogs/canines to determine the toxicity and toxicokinetic behavior of your compound.
  • Repeat Dose Intravenous Infusion Study - Other Species Conduct a repeat dose intravenous infusion study in other species to determine the toxicity and toxicokinetic behavior of your compound.
  • Repeat Dose Intravenous Infusion Study - Rats Conduct a repeat dose intravenous infusion study in rats to determine the toxicity and toxicokinetic behavior of your compound.
  • Single Dose Acute Intranasal Study - Dog / Canine Conduct a single dose intranasal study in dogs/canines to determine the toxicokinetic behavior of your compound.
  • Single Dose Acute Intranasal Study - Mouse Conduct a single dose intranasal study in mice to determine the toxicokinetic behavior of your compound.
  • Single Dose Acute Intranasal Study - Other Species Conduct a single dose intranasal study in other species to determine the toxicokinetic behavior of your compound.
  • Single Dose Acute Intranasal Study - Rat Conduct a single dose intranasal study in rats to determine the toxicokinetic behavior of your compound.
  • Single Dose Acute Intravenous Infusion Study - Dog / Canine Conduct a single dose intravenous infusion study in dogs/canines to determine the toxicokinetic behavior of your compound.
  • Single Dose Acute Intravenous Infusion Study - Other Species Conduct a single dose intravenous infusion study in other species to determine the toxicokinetic behavior of your compound.
  • Single Dose Acute Intravenous Infusion Study - Rats Conduct a single dose intravenous infusion study in rats to determine the toxicokinetic behavior of your compound.
  • Topical Dermal Toxicity and/or Toxicokinetic Study - Dog / Canine Conduct a dermal study to determine the toxicity and/or toxicokinetic behavior of your compound when applied topically to dogs/canines.
  • Topical Dermal Toxicity and/or Toxicokinetic Study - Minipig Conduct a dermal study to determine the toxicity and/or toxicokinetic behavior of your compound when applied topically to minipigs.
  • Topical Dermal Toxicity and/or Toxicokinetic Study - Mouse Conduct a dermal study to determine the toxicity and/or toxicokinetic behavior of your compound when applied topically to mice.
  • Topical Dermal Toxicity and/or Toxicokinetic Study - Other Species Conduct a dermal study to determine the toxicity and/or toxicokinetic behavior of your compound when applied topically to other species.
  • Topical Dermal Toxicity and/or Toxicokinetic Study - Rabbit Conduct a dermal study to determine the toxicity and/or toxicokinetic behavior of your compound when applied topically to rabbits.
  • Topical Dermal Toxicity and/or Toxicokinetic Study - Rat Conduct a dermal study to determine the toxicity and/or toxicokinetic behavior of your compound when applied topically to rats.
  • Topical Ocular Toxicity and/or Toxicokinetic Study - Dog / Canine Conduct a topical ocular toxicity study in dogs/canines to determine the toxicity and toxicokinetic behavior of your compound.
  • Topical Ocular Toxicity and/or Toxicokinetic Study - Minipig Conduct a topical ocular toxicity study in minipigs to determine the toxicity and toxicokinetic behavior of your compound.
  • Topical Ocular Toxicity and/or Toxicokinetic Study - Monkey / Non-human Primate Conduct a topical ocular toxicity study in monkeys/non-human primates to determine the toxicity and toxicokinetic behavior of your compound.
  • Topical Ocular Toxicity and/or Toxicokinetic Study - Mouse Conduct a topical ocular toxicity study in mice to determine the toxicity and toxicokinetic behavior of your compound.
  • Topical Ocular Toxicity and/or Toxicokinetic Study - Rabbit, Non-pigmented (New Zealand White; NZW) Conduct a topical ocular toxicity study in non-pigmented rabbits to determine the toxicity and toxicokinetic behavior of your compound.
  • Topical Ocular Toxicity and/or Toxicokinetic Study - Rabbit, Pigmented (Dutch Belted, New Zealand Red) Conduct a topical ocular toxicity study in pigmented rabbits to determine the toxicity and toxicokinetic behavior of your compound.

Testing Services

  • In Vitro Toxicology Testing Non-animal testing employing US and international methodologies for determining irritation and other undesirable potentials.

Other services

  • New Request  

Service areas:

DMPK Pharmacology Toxicology

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • United States Fort Collins, Larimer 2 sites

Source: Scientist.com supplier network (site locations)

About this supplier

In the supplier's own words, as listed in the Scientist.com network.

CARE Research, LLC is a preclinical contract research lab offers exploratory in-vivo research, PK/TK, range finding, toxicity studies, safety pharmacology, device development, and ADME studies. CARE Research is a large facility in Colorado offering a variety of animal models: mouse, rat, rabbit, dog, pig sheep and others. We have a well-equipped surgical suite which can be used for device testing studies.

Professional associations
Colorado BioScience Association, SOT
Website
www.careresearchllc.com

Source: Scientist.com supplier network, written by the supplier

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Sources: Scientist.com supplier network.

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