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Coriolis Pharma

Coriolis Pharma is listed as a mid sized business research supplier in the Scientist.com network, with 1 site in 1 country and 1 service area.

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Sites 1
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Mid sized business

Chemical and Compound Analysis

  • API Physical Characteristics Characterize physical and chemical properties of new drug molecules to develop safe, effective, and stable dosage forms.
  • Chemical Stability Measure the stability of small molecules in solution.
  • Circular Dichroism Examine the secondary structure and folding properties of proteins in solution.
  • Dynamic Light Scattering Determine the size of particles and extent of molecular aggregation in a suspension.
  • Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
  • Excipient Compatibility Test excipients for drug formulation, effects of temperature, time, humidity, pH and light exposure as well as excipient release.
Show all 21 in Chemical and Compound Analysis 15 more
  • High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
  • Isothermal Titration Calorimetry An ITC assay will be established and optimised for the affinity measurement of test substance to target molecule.
  • Liquid Chromatography Separate substances using a mobile and stationary phase.
  • Melting Point Use melting point analysis to characterize compounds based on calorimetry and thermodynamic data.
  • Nano-High Performance Liquid Chromatography Separate and detect low levels of analytes.
  • Particle Size Analysis Measure particle size distribution and characterize particle size, porosity and composition.
  • Photostability Measure drug degradation rates after exposure to various light sources.
  • Process Residual Impurities Detection Measure trace levels of impurities.
  • Protein Melting Point Analysis Assess protein stability by Differential Scanning Calorimetry (DSC) or Fluorimetry (Thermofluor) methods.
  • Protein Separation and Detection Separate proteins based on properties such as solubility, adsorption or size differences.
  • Raman Spectroscopy Use spectroscopic technique to observe vibrational, rotational and other low-frequency modes in a system.
  • Scanning and Transmission Electron Microscopy Examine the fine structures of molecules, cells and tissues with sub-nanometer resolution.
  • Size Exclusion Chromatography Separate and identify analytes based on their molecular size.
  • Solubility Studies Analyze substances for kinetics of solubility using nephelometry and UV-Vis spectrometry.
  • Static Light Scattering Use scattered light intensity to determine the average molecular weight of biopolymers.

Chemistry, Manufacturing and Controls (CMC)

  • API Stress Testing Studies Develop analytical methods to predict stability problems and identify degradation products/pathways under forced degradation conditions.
  • API/ Excipients Compatibility Studies Delineate real and possible interactions between potential formulation excipients and the API as an important risk reduction exercise early in formulation development.
  • Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
  • Drug Formulation Combine substances including the active drug into a final product with the desired metabolic and therapeutic properties.
  • Drug Product Stability Use accelerated stress conditions to determine degradation pathways and identify manufacturing issues.
  • Excipients Acquire synthetic or natural inert components to formulate therapeutic agents.
Show all 9 in Chemistry, Manufacturing and Controls (CMC) 3 more
  • Formulation Services Assistance when determining the look, texture, fragrance of a product with compatibility with product packaging, knowledge of competitive performance traits and product shelf life.
  • Lyophilization Lyophilization, also known as freeze-drying, is a dehydration process typically used to preserve perishable materials
  • Thermal Analysis Characterize compounds based on calorimetry and thermodynamic data.
Show all 46 services 34 more

Discovery Chemistry

  • Impurity Synthesis Use high resolution MS or NMR to eliminate intermediates or organic byproducts and determine impurity content.
  • LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.

DNA & RNA

  • Capillary Electrophoresis Separate ng quantities of DNA to single base resolution.
  • DNA-lipid interaction analysis Investigate cellular dynamics based on changes in fluorescent properties.

In Vitro Assays

  • Endpoint Dilution Assay (TCID50) Assay Determine the viral titer to induce cell death in half the cell population of an inoculated tissue culture.

Nanotechnology

  • Liposomes Create artificial spherical vesicles that can be used as a vehicle for administration of drugs.

Protein Sciences

  • Analytical Ultracentrifugation Characterize the interactions and properties of macromolecules in solution.
  • Protein Post-translational Modification Analysis Measure glycosylation, phosphorylation, sulfation, ubiquitination, methylation and acetylation.
  • Protein Sequencing Determine the amino acid sequence of protein or peptide.

Testing Services

  • Accelerated Stability Determine shelf life of drug formulations by comparing API breakdown at elevated temperature.
  • Elevated Temperature Stability Determine the stability of a product at elevated temperature.
  • Freeze-Thaw Testing Use freeze-thaw cycling to measure the long-term durability of cosumer products.
  • Package Compatibility Tests Ensure that the consumer product is not adversely affected by the package components and vice versa.
  • PAO Stability Trial Assess the stability of a consumer product under certain storage conditions.
  • Real-time Stability Test Assure stability and physical integrity of consumer products in real-time conditions.

Other services

  • New Request  

Service areas:

Chemistry

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • Germany Martinsried 1 site

Source: Scientist.com supplier network (site locations)

About this supplier

In the supplier's own words, as listed in the Scientist.com network.

Coriolis Pharma offers analytical method development, formulation development, forced degradation, stability testing, lyophilization, and pre-clinical materials supply services.

Website
www.coriolis-pharma.com

Source: Scientist.com supplier network, written by the supplier

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Sources: Scientist.com supplier network.

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