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Coriolis Pharma
Coriolis Pharma is listed as a mid sized business research supplier in the Scientist.com network, with 1 site in 1 country and 1 service area.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Mid sized business
Chemical and Compound Analysis
- API Physical Characteristics Characterize physical and chemical properties of new drug molecules to develop safe, effective, and stable dosage forms.
- Chemical Stability Measure the stability of small molecules in solution.
- Circular Dichroism Examine the secondary structure and folding properties of proteins in solution.
- Dynamic Light Scattering Determine the size of particles and extent of molecular aggregation in a suspension.
- Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
- Excipient Compatibility Test excipients for drug formulation, effects of temperature, time, humidity, pH and light exposure as well as excipient release.
Show all 21 in Chemical and Compound Analysis
- High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
- Isothermal Titration Calorimetry An ITC assay will be established and optimised for the affinity measurement of test substance to target molecule.
- Liquid Chromatography Separate substances using a mobile and stationary phase.
- Melting Point Use melting point analysis to characterize compounds based on calorimetry and thermodynamic data.
- Nano-High Performance Liquid Chromatography Separate and detect low levels of analytes.
- Particle Size Analysis Measure particle size distribution and characterize particle size, porosity and composition.
- Photostability Measure drug degradation rates after exposure to various light sources.
- Process Residual Impurities Detection Measure trace levels of impurities.
- Protein Melting Point Analysis Assess protein stability by Differential Scanning Calorimetry (DSC) or Fluorimetry (Thermofluor) methods.
- Protein Separation and Detection Separate proteins based on properties such as solubility, adsorption or size differences.
- Raman Spectroscopy Use spectroscopic technique to observe vibrational, rotational and other low-frequency modes in a system.
- Scanning and Transmission Electron Microscopy Examine the fine structures of molecules, cells and tissues with sub-nanometer resolution.
- Size Exclusion Chromatography Separate and identify analytes based on their molecular size.
- Solubility Studies Analyze substances for kinetics of solubility using nephelometry and UV-Vis spectrometry.
- Static Light Scattering Use scattered light intensity to determine the average molecular weight of biopolymers.
Chemistry, Manufacturing and Controls (CMC)
- API Stress Testing Studies Develop analytical methods to predict stability problems and identify degradation products/pathways under forced degradation conditions.
- API/ Excipients Compatibility Studies Delineate real and possible interactions between potential formulation excipients and the API as an important risk reduction exercise early in formulation development.
- Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
- Drug Formulation Combine substances including the active drug into a final product with the desired metabolic and therapeutic properties.
- Drug Product Stability Use accelerated stress conditions to determine degradation pathways and identify manufacturing issues.
- Excipients Acquire synthetic or natural inert components to formulate therapeutic agents.
Show all 9 in Chemistry, Manufacturing and Controls (CMC)
- Formulation Services Assistance when determining the look, texture, fragrance of a product with compatibility with product packaging, knowledge of competitive performance traits and product shelf life.
- Lyophilization Lyophilization, also known as freeze-drying, is a dehydration process typically used to preserve perishable materials
- Thermal Analysis Characterize compounds based on calorimetry and thermodynamic data.
Show all 46 services
Discovery Chemistry
- Impurity Synthesis Use high resolution MS or NMR to eliminate intermediates or organic byproducts and determine impurity content.
- LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
DNA & RNA
- Capillary Electrophoresis Separate ng quantities of DNA to single base resolution.
- DNA-lipid interaction analysis Investigate cellular dynamics based on changes in fluorescent properties.
In Vitro Assays
- Endpoint Dilution Assay (TCID50) Assay Determine the viral titer to induce cell death in half the cell population of an inoculated tissue culture.
Nanotechnology
- Liposomes Create artificial spherical vesicles that can be used as a vehicle for administration of drugs.
Protein Sciences
- Analytical Ultracentrifugation Characterize the interactions and properties of macromolecules in solution.
- Protein Post-translational Modification Analysis Measure glycosylation, phosphorylation, sulfation, ubiquitination, methylation and acetylation.
- Protein Sequencing Determine the amino acid sequence of protein or peptide.
Testing Services
- Accelerated Stability Determine shelf life of drug formulations by comparing API breakdown at elevated temperature.
- Elevated Temperature Stability Determine the stability of a product at elevated temperature.
- Freeze-Thaw Testing Use freeze-thaw cycling to measure the long-term durability of cosumer products.
- Package Compatibility Tests Ensure that the consumer product is not adversely affected by the package components and vice versa.
- PAO Stability Trial Assess the stability of a consumer product under certain storage conditions.
- Real-time Stability Test Assure stability and physical integrity of consumer products in real-time conditions.
Other services
- New Request
Service areas:
Where it operates
Sites by country, with the cities in each.
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Germany 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Coriolis Pharma offers analytical method development, formulation development, forced degradation, stability testing, lyophilization, and pre-clinical materials supply services.
- Website
- www.coriolis-pharma.com
Work with Coriolis Pharma on Scientist.com
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