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Champions Oncology
Champions Oncology is listed as a mid sized business research supplier in the Scientist.com network, with 3 sites in 1 country and 1 service area.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Mid sized business
Bioimaging
- In Vivo Whole Tissue and Animal Imaging Visualize, analyze and track light producing reporters in whole animals.
Biomarkers
- Biomarker Analytical Validation Assess and optimize the characteristics of a candidate biomarker to ensure reproducibility and consistency.
- Biomarker Clinical Validation Evaluate the predictive ability of a candidate biomarker for a disorder.
- Biomarker Discovery Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.
- Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
- Diagnostic Biomarkers Discovery Identify candidate biomarkers indicative of the presence of a disorder.
- Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
Show all 13 in Biomarkers
- Immunohistochemistry Examine the toxic effects of pre-clinical compounds in small animal and patient histological samples.
- Immunophenotyping Separate cell types based on their expression of biomarkers or based on their individual and unique expression patterns.
- Pharmacodynamic Biomarkers Discovery Identify candidate biomarkers indicative of the therapeutic outcome of a drug-target interaction.
- Predictive Biomarkers Discovery Identify candidate biomarkers suggestive of a response to a treatment.
- Prognostic Biomarkers Discovery Identify candidate biomarkers representative of disease progression without treatment.
- Propidium Iodide FACS Analysis Use DNA staining and flow cytometry to analyze the cell cycle and detect apoptosis or cell proliferation.
- Solid Tumor CDx Design and validate companion diagnostics for solid tumors that help select the most appropriate patients, identify patients at increased risk, or monitor treatment effectiveness.
Chemical and Compound Testing
- Clinical Pathology Diagnose disease based on the laboratory analysis of bodily fluids, such as blood, urine and tissues.
Clinical Consulting
- Clinical Consulting Provide high quality data, on time and within budget, while maintaining the flexibility in delivering personalized services.
- Clinical Study Reporting (CSR) Report results of clinical trials to regulatory agencies. This includes participant flow, baseline characteristics, outcome measures, statistical analyses, and adverse events.
- Clinical Trial Consulting Consulting services for Clinical trials.
- Clinical Trial Feasibility Request services related to Clinical Trial Design and feasibility.
Show all 73 services
Clinical Trials
- Bioequivalence Studies Assess the expected biological equivalence of two proprietary preparations of a drug.
- Clinical Trial Design Develop study-related protocols, case report forms (CRFs) and database tools for records management.
Data Science/Bioinformatics
- Clinical Biomarker Analysis An approach to finding markers that change in response to a drug or that identify a group that responds favorably to a specific therapy. These can be omics, molecular, histologic, radiologic, etc.
- Clinical Data Analysis Analysis that helps you make sense of your clinical data
- In Silico Cancer Genomics/Cancer Transcriptomics Analysis Interpret DNA sequencing and microarray data for cancer studies.
- In Silico Drug-Drug Interactions Use computational tools to predict pharmaceutical, pharmacodynamic or pharmacokinetic drug-drug interactions to maximize drug regimen safety.
- In Silico Protein Sequence Analysis Use software to predict protein structural and functional features and secondary structure components.
Discovery Chemistry
- In Silico Lead Optimization Use in silico design to enhance the ADME-PK properties of candidate drugs to maximize efficacy and safety.
- Virtual Screening Use software algorithms to virtually screen millions of potential compounds and peptides for binding.
Disease Models
- Pregnancy Models Measure therapeutic endpoints in animal models of pregnancy.
DNA & RNA
- DNA Sequencing Determine the nucleotide sequence of DNA samples.
- Exome Sequencing Determine protein-coding nucleotide sequences in a DNA sample.
- NGS: Next Generation Sequencing Sequence millions of template DNA molecules in parallel.
- RNA Sequencing Use Next Generation Sequencing techniques to Identify RNA transcripts, examine differential expression patterns and analyze splice variants.
- RNA Sequencing/Resequencing Identify RNA transcripts, examine differential expression patterns and analyze splice variants.
- Whole Genome Sequencing Determine the entire genetic make-up of an organism.
Drug Development
- Bioinformatics Consulting Consulting Services for the science of collecting and analyzing complex biological data
General in vivo Toxicology
- Single Maximum Tolerated Dose (MTD) Mouse Study Use mouse models to determine the MTD of a drug candidate by a single administration in a 7 day period.
- Single Maximum Tolerated Dose (MTD) Rat Study Use rat models to determine the MTD of a drug candidate by a single administration in a 7 day period.
Human Biological Samples
- Biospecimen Finder Explore listings of Human Biological Samples from the suppliers on the scientist.com HBS database
- HBS: Human Biological Samples Request human biosamples including tissues, blood, serum, bone marrow, tissue microarrays, etc.
In Vitro Assays
- Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
- BrdU S-Phase Analysis Assess cell division or apoptosis by measuring thymidine-analog label incorporation during DNA replication.
- Cytometric Bead Array (CBA) FACS Analysis Use flow cytometry and antibody-coated beads to simultaneously detect multiple target proteins.
- PrimeFlow™ RNA Assay Reveal the unique kinetics of mRNA and protein in the same cell and identify expression differences as they change over time in response to stimulus.
In Vitro Pharmacology
- In Vitro Oncology Models Use cell-based and biochemical models of cancer.
- Target Identification Identify the target(s) of a biologically active substance.
- Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.
In Vivo Pharmacokinetics
- In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
- In Vivo PK Consulting Expert advice on pharmacokinetics and how specific drugs affect the body to determine function, effectiveness, dosage size, etc…
- Pharmacokinetic (PK) Screening - Mouse Run pharmacokinetic studies in mice that measure a drug's absorption, distribution, metabolism and excretion.
- Repetitive Maximum Tolerated Dose (MTD) Mouse Study Use mouse models to determine the MTD of a drug candidate by repetitive administrations for 7 days.
- Repetitive Maximum Tolerated Dose (MTD) Rat Study Use rat models to determine the MTD of a drug candidate by repetitive administrations for 7 days.
Model Development
- Animal Model Development Create new systems for profiling pre-clinical therapeutics, devices, and surgical techniques.
Oncology Models
- Athymic Mouse Use a single animal species to create one or more disease models for cachexia and spontaneous cancer.
- Cachexia Models Measure therapeutic endpoints in animal models of cachexia.
- Immuno-PDX Utilize the patient-derived xenograft for drug response profiling and biomarker discovery of immuno-oncology drug candidates.
- Leukemia PDX Measure therapeutic endpoints in patient-derived xenografts of leukemia.
- Oncology Derived PDX Patient derived xenografts derived from various oncological samples. This includes, but is not limited to, samples from Lymphoma, Melanoma, and Leukemia.
- Oncology Models Use model organisms to test the therapeutic efficacy of cancer drug candidates.
Show all 10 in Oncology Models
- Oncology Xenografts Xenografts derived from oncological samples.
- Ovarian Cancer Mouse Measure therapeutic endpoints in animal models of ovarian cancer.
- Renal Xenograft Measure therapeutic endpoints in renal models of cancer.
- Xenograft Models Measure therapeutic endpoints in cancer models using tumor cells transplanted from a donor of a different species.
Protein Sciences
- ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
- Proteomics Do large-scale experimental analysis of proteins focused on understanding structure and function.
Scientific Data Services
- Bioinformatics Bioinformatics is a powerful method of storing, retrieving and analyzing biological data.
- Cancer Systems Biology Convert complex molecular data obtained from high-throughput technologies to deducible information.
- Cloud Computing Request on-demand computer resources specifically relating to large data storage and computing power.
- In Silico Genomics/Transcriptomics Data Analysis Interpret DNA sequencing and microarray data.
- In Silico Metagenomics/Metatranscriptomics Data Analysis Use software to analyze genomic information from multiple environmental sources.
- Machine Learning/ AI Predict and model an outcome (e.g. disease progression) based on input variables (i.e. features.)
Testing Services
- ASTM E1207: Antiperspirant Clinical Testing Determine antiperspirant efficacy for products (e.g. deodorant) that are intended to be applied to the underarm.
Other services
- New Request
Service areas:
Where it operates
Sites by country, with the cities in each.
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United States 3 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Champions Oncology, Inc. is engaged in the development of advanced technology solutions and services to personalize the development and use of oncology drugs. The Champions TumorGraft® (CTG) platform is a novel approach based upon the implantation of primary human tumors in immune-deficient mice followed by propagation of the resulting engraftments, or TumorGrafts, in a manner that preserves the biological characteristics of the original human tumor. Champions is building its CTG platform through the procurement, development and characterization of TumorGrafts within multiple cancer types...
Show the full description
Champions Oncology, Inc. is engaged in the development of advanced technology solutions and services to personalize the development and use of oncology drugs. The Champions TumorGraft® (CTG) platform is a novel approach based upon the implantation of primary human tumors in immune-deficient mice followed by propagation of the resulting engraftments, or TumorGrafts, in a manner that preserves the biological characteristics of the original human tumor.
Champions is building its CTG platform through the procurement, development and characterization of TumorGrafts within multiple cancer types. Champions TumorGrafts® are procured through agreements with a number of institutions in the U.S. and overseas, as well as through the company’s Personalized Oncology Solutions business.
Champions provides Personalized Oncology Solutions, or POS, to oncologists by establishing and administering expert tumor panels for their patients to analyze medical records and test results, to assist in understanding conventional and experimental options and to identify and arrange for testing, analysis and study of the patients’ cancer tissues, as appropriate. Additionally, the company offers Personalized TumorGraft development, drug studies and genome sequencing as part of our POS, whereby physicians can evaluate the effects of cancer drugs on their patients’ Personalized TumorGrafts and understand the genetic makeup of each patient’s tumor, enabling them to better select treatment regimens that may be efficacious to the patient.
As the company expanded its number of TumorGraft models, it began offering leading pharmaceutical and biotechnology companies the benefits of its Champions TumorGraft® platform for oncology development programs. Champions provides Translational Oncology Solutions, or TOS, that are predictive of clinical outcomes and that might provide for a faster and less expensive path to drug approval. These services utilize Champions TumorGrafts® to evaluate tumor sensitivity/resistance to various single, combination, standard and novel chemotherapy agents. TOS also includes biomarker discovery and the identification of novel drug combinatio
- Website
- championsoncology.com
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