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Research supplier
Pixl Bio
Pixl Bio is listed as a small business research supplier in the Scientist.com network, with 4 sites in 2 countries and 1 service area.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Bioimaging
- Confocal/Optical Microscopy Use optical imaging technique to increase optical resolution and contrast of a micrograph.
- Microscopy Use microscopy to analyze surfaces of biological materials and to develop 3D images of biological structures.
Cell Culture and Characterization
- 3D Cell Culture Use a scaffold-based or scaffold-free format to grow three dimensional cell and tissue structures.
- Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
- Cell Line Characterization Track source history and characterize cell lines to establish identity, purity and stability.
- Gene-Edited iPSCs Disease Models Use gene-edited iPSCs to model human diseases.
- Induced Pluripotent Stem (iPS) Cell Reprogramming Generate induced pluripotent stem cells from adult somatic cells.
- Isogenic Knockout iPSC Lines Mimic loss of function of genes associated with various diseases and disorders.
Show all 7 in Cell Culture and Characterization
- Stem Cell Differentiation Acquire specialized cells from differentiated stem cells.
Data Science/Bioinformatics
- Discovery In Silico Drug Dynamics Develop In Silico model of a drug candidate with a biological system with applications such as Pro-drug Predictions, ADME-PK Due Diligence, Brain-Barrier Permeability Simulation, Drug Absorption Simulation, In Silico...
- Discovery Machine Learning/AI Complex analytical approaches to find patterns and make predictions in drug discovery projects.
- Translational Machine Learning/AI Complex analytical approaches to find patterns and make predictions in drug discovery projects.
Discovery Chemistry
- Natural Product Screening Screen large natural product collections for therapeutic activity.
Show all 46 services
Disease Models
- Drug-Induced Liver Injury (DILI) Toxicity Assays Use biochemical, cell-based or in vivo assays to measure toxicity from drug-induced liver injury.
- Hepatitis C Virus Models Measure therapeutic endpoints in animal models of Hepatitis C virus infection.
- Respiratory Models Test therapeutic efficacy of drug candidate in respiratory disease model.
DNA & RNA
- CRISPR Using advanced CRISPR technology, add or delete base pairs at a specifically targeted DNA loci.
- Genome Editing Use CRISPR, ZFN, TALEN or AAV gene targeting for targeted gene mutations and creation of transgenics.
- Knockout/Knockin Cell Lines Develop Knockout/Knockin Cell Line.
Human Biological Samples
- Biospecimen Finder Explore listings of Human Biological Samples from the suppliers on the scientist.com HBS database
- FRBESaHBS Request human biosamples including tissues, blood, serum, bone marrow, and tissue microarrays.
- HBS: Human Biological Samples Request human biosamples including tissues, blood, serum, bone marrow, tissue microarrays, etc.
- Human Adult Stem Cells Acquire human stem cells isolated from various adult tissues.
- Human iPSC's For requesting human sourced induced pluripotent stem cells.
In Vitro ADME
- CYP Inhibition Assay Assess the inactivation and inhibition of cytochrome P450 (CYP450) in microsomes isolated from primary human hepatocytes or liver.
In Vitro Assays
- 3D Cell Microscopy Assay Investigate cellular and subcellular events in three dimensional 3D cultures by using fluorescence microscopy.
- Assay Development Construct or create new assays or modify existing ones.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Cell Painting Cell painting is multiplexed image-based assay used to investigate subtle changes in cellular homeostasis
- Cell-based Screening Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- High Content Screening Analyze whole cells or components of cells with simultaneous readout of several parameters.
Show all 8 in In Vitro Assays
- In Vitro Efficacy Test Use in vitro models to test the efficacy of your products.
- Phenotype Assays Measure effects of drug candidate on the morphology or function of cells and whole animals.
In Vitro Pharmacology
- Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
- In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
In Vitro Toxicology
- Cardiomyocyte Toxicity Assess cytotoxic effects of pre-clinical compounds on cardiomyocytes.
- Cardiotoxicity Evaluate the effect of a compound on heart electrophysiology and muscle function.
- Cytotoxicity Test for effects on cell viability and proliferation
- Cytotoxicity Testing Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.
- Hepatocyte Toxicity Assess the cytotoxic effects of pre-clinical compounds on hepatocytes purified from patients and animal models.
Other Specialty Toxicology
- Biosafety Testing In Vitro Test biologics, raw materials, lot release and viral safety
Safety Pharmacology
- Endocrine Disruptor Screening Use biochemical, cell based or in vivo assays to identify and quantify endocrine-modulating agents.
- Safety Screen Panel Assays Safety Pharmacology safety screen panel assays enable early identification of significant off-target interactions with your compound(s)
- Target Safety Assessment Understand the role of your drug target and assess risks in normal physiology.
Scientific Data Services
- Automated Image Analysis Automated Image Analysis
- Machine Learning/ AI Predict and model an outcome (e.g. disease progression) based on input variables (i.e. features.)
Service areas:
Where it operates
Sites by country, with the cities in each.
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Sweden 2 sites
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United Kingdom 2 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
he TESARO team has a track record of success in identifying, acquiring, developing and commercializing oncology therapeutics and supportive care products that make a meaningful difference in the lives of patients.
Our interests are aligned with those of our partners, and we have a proven track record of successful product development and global commercialization. We are selective in the number and type of alliances that we participate in, thus enabling us to provide a high level of attention to each partner and product.
- Website
- www.pixl.bio
Work with Pixl Bio on Scientist.com
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