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Pixl Bio

Pixl Bio is listed as a small business research supplier in the Scientist.com network, with 4 sites in 2 countries and 1 service area.

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Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 4
Countries 2

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Small business

Bioimaging

  • Confocal/Optical Microscopy Use optical imaging technique to increase optical resolution and contrast of a micrograph.
  • Microscopy Use microscopy to analyze surfaces of biological materials and to develop 3D images of biological structures.

Cell Culture and Characterization

  • 3D Cell Culture Use a scaffold-based or scaffold-free format to grow three dimensional cell and tissue structures.
  • Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
  • Cell Line Characterization Track source history and characterize cell lines to establish identity, purity and stability.
  • Gene-Edited iPSCs Disease Models Use gene-edited iPSCs to model human diseases.
  • Induced Pluripotent Stem (iPS) Cell Reprogramming Generate induced pluripotent stem cells from adult somatic cells.
  • Isogenic Knockout iPSC Lines Mimic loss of function of genes associated with various diseases and disorders.
Show all 7 in Cell Culture and Characterization 1 more
  • Stem Cell Differentiation Acquire specialized cells from differentiated stem cells.

Data Science/Bioinformatics

  • Discovery In Silico Drug Dynamics Develop In Silico model of a drug candidate with a biological system with applications such as Pro-drug Predictions, ADME-PK Due Diligence, Brain-Barrier Permeability Simulation, Drug Absorption Simulation, In Silico...
  • Discovery Machine Learning/AI Complex analytical approaches to find patterns and make predictions in drug discovery projects.
  • Translational Machine Learning/AI Complex analytical approaches to find patterns and make predictions in drug discovery projects.

Discovery Chemistry

  • Natural Product Screening Screen large natural product collections for therapeutic activity.
Show all 46 services 34 more

Disease Models

  • Drug-Induced Liver Injury (DILI) Toxicity Assays Use biochemical, cell-based or in vivo assays to measure toxicity from drug-induced liver injury.
  • Hepatitis C Virus Models Measure therapeutic endpoints in animal models of Hepatitis C virus infection.
  • Respiratory Models Test therapeutic efficacy of drug candidate in respiratory disease model.

DNA & RNA

  • CRISPR Using advanced CRISPR technology, add or delete base pairs at a specifically targeted DNA loci.
  • Genome Editing Use CRISPR, ZFN, TALEN or AAV gene targeting for targeted gene mutations and creation of transgenics.
  • Knockout/Knockin Cell Lines Develop Knockout/Knockin Cell Line.

Human Biological Samples

  • Biospecimen Finder Explore listings of Human Biological Samples from the suppliers on the scientist.com HBS database
  • FRBESaHBS Request human biosamples including tissues, blood, serum, bone marrow, and tissue microarrays.
  • HBS: Human Biological Samples Request human biosamples including tissues, blood, serum, bone marrow, tissue microarrays, etc.
  • Human Adult Stem Cells Acquire human stem cells isolated from various adult tissues.
  • Human iPSC's For requesting human sourced induced pluripotent stem cells.

In Vitro ADME

  • CYP Inhibition Assay Assess the inactivation and inhibition of cytochrome P450 (CYP450) in microsomes isolated from primary human hepatocytes or liver.

In Vitro Assays

  • 3D Cell Microscopy Assay Investigate cellular and subcellular events in three dimensional 3D cultures by using fluorescence microscopy.
  • Assay Development Construct or create new assays or modify existing ones.
  • Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
  • Cell Painting Cell painting is multiplexed image-based assay used to investigate subtle changes in cellular homeostasis
  • Cell-based Screening Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
  • High Content Screening Analyze whole cells or components of cells with simultaneous readout of several parameters.
Show all 8 in In Vitro Assays 2 more
  • In Vitro Efficacy Test Use in vitro models to test the efficacy of your products.
  • Phenotype Assays Measure effects of drug candidate on the morphology or function of cells and whole animals.

In Vitro Pharmacology

  • Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
  • In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.

In Vitro Toxicology

  • Cardiomyocyte Toxicity Assess cytotoxic effects of pre-clinical compounds on cardiomyocytes.
  • Cardiotoxicity Evaluate the effect of a compound on heart electrophysiology and muscle function.
  • Cytotoxicity Test for effects on cell viability and proliferation
  • Cytotoxicity Testing Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.
  • Hepatocyte Toxicity Assess the cytotoxic effects of pre-clinical compounds on hepatocytes purified from patients and animal models.

Other Specialty Toxicology

  • Biosafety Testing In Vitro Test biologics, raw materials, lot release and viral safety

Safety Pharmacology

  • Endocrine Disruptor Screening Use biochemical, cell based or in vivo assays to identify and quantify endocrine-modulating agents.
  • Safety Screen Panel Assays Safety Pharmacology safety screen panel assays enable early identification of significant off-target interactions with your compound(s)
  • Target Safety Assessment Understand the role of your drug target and assess risks in normal physiology.

Scientific Data Services

  • Automated Image Analysis Automated Image Analysis
  • Machine Learning/ AI Predict and model an outcome (e.g. disease progression) based on input variables (i.e. features.)

Service areas:

Biology

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • Sweden Uppsala 2 sites
  • United Kingdom Cambridge 2 sites

Source: Scientist.com supplier network (site locations)

About this supplier

In the supplier's own words, as listed in the Scientist.com network.

he TESARO team has a track record of success in identifying, acquiring, developing and commercializing oncology therapeutics and supportive care products that make a meaningful difference in the lives of patients.

Our interests are aligned with those of our partners, and we have a proven track record of successful product development and global commercialization. We are selective in the number and type of alliances that we participate in, thus enabling us to provide a high level of attention to each partner and product.

Website
www.pixl.bio

Source: Scientist.com supplier network, written by the supplier

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Sources: Scientist.com supplier network.

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