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Research supplier
Abpro
Abpro is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country and 1 service area.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Antibodies
- Antibody Humanization Increase an antibody's similarity to a variant produced naturally in humans.
- Antibody Purification Purify multiple antibody types including IgG, IgM, IgA and IgY.
- Antibody Sequencing Sequence cDNA encoding variable heavy (VH) and variable light (VL) domains of a hybridoma cell line.
- Custom Antibodies Design and produce polyclonal and monoclonal antibodies.
- Epitope Mapping Map the antibody-antigen binding region to define protein-protein interaction sites.
- In Vitro Monoclonal Antibody Production Generate monoclonal antibodies in vitro using cultured antibody-secreting hybridoma cell lines.
Bioimaging
- In Vivo Whole Tissue and Animal Imaging Visualize, analyze and track light producing reporters in whole animals.
- Luminescence Imaging Monitor biological processes and pathologies using reporter proteins such as firefly and Renilla luciferase.
- Microscopy Use microscopy to analyze surfaces of biological materials and to develop 3D images of biological structures.
Biomarkers
- Cell Migration Assays Measure chemotaxis, haptotaxis, transmigration and wound-healing.
- Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
- Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
- Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
- Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
Show all 71 services
Cell Culture and Characterization
- Cell Culture Culture primary or immortalized cell lines.
Chemical and Compound Analysis
- Immunoaffinity Chromatography Use antibody-antigen interactions to isolate and concentrate analytes.
- Non GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
Clinical Trials
- Bioequivalence Studies Assess the expected biological equivalence of two proprietary preparations of a drug.
Disease Models
- Arthritis Models Measure therapeutic endpoints in animal models of arthritis.
- Blood Models Test for therapeutic efficacy of drug candidates in blood disorder models.
- Huntington's Disease Models Measure therapeutic endpoints in animal models of Huntington's disease.
- Inflammation Models Measure therapeutic endpoints in animal models for inflammation.
- Inflammatory Bowel Disease Models Measure IBD symptom severity, cytokine levels and body weight, and evaluate IHC and Ariol images.
- Liver Disease Animal Models Measure therapeutic endpoints in animal models with liver disease.
Show all 13 in Disease Models
- LPS Acute Response Models Measure therapeutic endpoints in acute models of inflammation.
- LPS Lung Inflammation Models Measure therapeutic endpoints in animal models of inflammation.
- Macular Degeneration Models Use a single animal species to create one or more models for eye disease.
- Microsurgery in Rodents Outsource microsurgeries projects required for testing new therapies on a rodent model.
- OVA Lung Inflammation Models Measure therapeutic endpoints in animal models of inflammation.
- Thrombosis Models Measure therapeutic endpoints in animal models of thrombosis.
- Wound Healing Models Measure therapeutic endpoints in animal models of wound healing.
General in vivo Toxicology
- General Toxicology Use in vivo models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.
- Oral Toxicology Use toxicity studies in animals to evaluate the oral toxicity of a drug candidate.
- Single Maximum Tolerated Dose (MTD) Mouse Study Use mouse models to determine the MTD of a drug candidate by a single administration in a 7 day period.
- Single Maximum Tolerated Dose (MTD) Rat Study Use rat models to determine the MTD of a drug candidate by a single administration in a 7 day period.
In Vitro Assays
- Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
- Apoptotic Cell Staining Detect apoptotic cells in culture.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Cell Based Assays Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
- Cell Proliferation Measure cell number, cell viability and cell division.
- Cytometric Bead Array (CBA) FACS Analysis Use flow cytometry and antibody-coated beads to simultaneously detect multiple target proteins.
Show all 8 in In Vitro Assays
- Hydroxyproline Assays Use biochemical, cell based or in vivo assays to quantify hydroxyproline or collagen in a sample.
- Luciferase Reporter Assay Evaluate promoter activity by measuring light output from the luciferase enzyme.
In Vitro Pharmacology
- HuGEMM - Immuno-Oncology Model Evaluate human-specific therapeutics for checkpoint inhibitors, including anti-human PD-1, anti-human PDL-1, and anti-human CTLA-4 antibodies.
In Vitro Toxicology
- ADCC and CDC Assay Services Measure toxicity of antibodies.
- Cytotoxicity Test for effects on cell viability and proliferation
In Vivo Pharmacokinetics
- In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
- In Vivo PK Consulting Expert advice on pharmacokinetics and how specific drugs affect the body to determine function, effectiveness, dosage size, etc…
- Pharmacokinetic (PK) Screening - Mouse Run pharmacokinetic studies in mice that measure a drug's absorption, distribution, metabolism and excretion.
- Pharmacokinetic (PK) Screening - Rat Run pharmacokinetic studies in rats that measure a drug's absorption, distribution, metabolism and excretion.
- Rat Efficacy Combination Use rat models to determine the anti-cancer efficacy and potential synergy of a drug candidate with a standard drug treatment.
- Rat Efficacy Monotherapy Use rat models to determine the anti-cancer efficacy of a drug candidate compared to a positive control.
Show all 8 in In Vivo Pharmacokinetics
- Repetitive Maximum Tolerated Dose (MTD) Mouse Study Use mouse models to determine the MTD of a drug candidate by repetitive administrations for 7 days.
- Repetitive Maximum Tolerated Dose (MTD) Rat Study Use rat models to determine the MTD of a drug candidate by repetitive administrations for 7 days.
Model Development
- Animal Model Development Create new systems for profiling pre-clinical therapeutics, devices, and surgical techniques.
- Knockin Mice Make targeted insertion of a gene of interest into a specific gene locus to create transgenic mice.
- Knockout Mice Create transgenic mice that are genetically engineered to inactivate a gene or set of genes.
- PBMC Humanized Mice Study and evaluate compounds for infectious diseases and graft rejection.
- Transgenic Models Create animal models engineered for use in a specific therapeutic area.
- Zucker Rat Use a single animal species to create one or more disease models for cachexia.
Oncology Models
- Oncology Models Use model organisms to test the therapeutic efficacy of cancer drug candidates.
- Ovarian Cancer Mouse Measure therapeutic endpoints in animal models of ovarian cancer.
- Renal Xenograft Measure therapeutic endpoints in renal models of cancer.
- Xenograft Models Measure therapeutic endpoints in cancer models using tumor cells transplanted from a donor of a different species.
Protein Sciences
- Antibody-Antigen Affinity Measurement Measure the binding kinetics of an antibody–antigen interaction.
- Cytokines Find recombinant cytokines or cytokine assays.
- Protein Expression Produce recombinant proteins in prokaryotic or eukaryotic systems.
- Protein Services Protein analysis and tagging are key steps in understanding the effects of compounds and treatments on your target disease outc...
- Western Blots Detect specific proteins in a sample of tissue homogenate or extract.
Target Animal and Human Food Safety
- Toxicokinetic Analysis Determine the drug concentration at which off-target or toxic effects occur.
Other services
- New Request
Service areas:
Where it operates
Sites by country, with the cities in each.
-
United States 2 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
High Speed Custom Monoclonal Antibody Generation At Abpro we have generated a mouse that optimizes hybrdidoma production. Using our proprietary HTP mouse and our state-of-the-art automated lab equipment, we have shortened the antibody production timeline to two months without sacrificing quality. With Abpro, making an antibody is a collaborative experience where we work together to develop an antibody that meets your needs and your timeline. We Offer: Quality Monoclonal Antibodies in Two Months Success rate of 95% Customized antigen design Bioinformatics Broad screening capabilities (ELISA...
Show the full description
High Speed Custom Monoclonal Antibody Generation
At Abpro we have generated a mouse that optimizes hybrdidoma production. Using our proprietary HTP mouse and our state-of-the-art automated lab equipment, we have shortened the antibody production timeline to two months without sacrificing quality.
With Abpro, making an antibody is a collaborative experience where we work together to develop an antibody that meets your needs and your timeline.
We Offer:
- Quality Monoclonal Antibodies in Two Months
- Success rate of 95%
- Customized antigen design
- Bioinformatics
- Broad screening capabilities (ELISA, WB, Flow, Binding, more upon request)
- Opportunity to test subclones and select specific hybridomas we deliver
- AAALAC International accredited animal facility
Superior Epitope Spread
Our HTP mouse has a more broad epitope spread than traditional mice. This allows Abpro to consistently deliver antibodies to traditionally difficult targets such as:
- Anti-Idiotype
- Peptides
- Proteins
- Conformation Specific
- High Homology Targets
- Cell Surface Proteins
- GPCRs
- 1-Amino Acid Spedificity
- Neo-Epitopes
- Tetraspanners
- Phospho-specific
Contact Abpro for more information
Please contact Abpro with any questions you may have. We like to communicate with our customers to understand their goals so that we can use our experience to design your project in such a way that will deliver quality antibodies that meet your timelines.
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Or give us a call at : [removed]
- Website
- www.abprobioresearch.com
Work with Abpro on Scientist.com
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