CEITEC Josef Dadok National NMR Centre

Investigation of the biomolecular structure and dynamics by NMR spectroscopy. Development of novel methodologies for biomolecular NMR spectroscopy (development of new pulse sequences with improved sensitivity and resolution, development of methods providing additional structural restraints, improvement of strategies for three-dimensional structure calculations and for analysis of the relaxation data in terms of biomolecular dynamics).

Unique Features

NMR (Nuclear Magnetic Resonance) spectroscopy is a key technology for research in modern life sciences allowing detailed investigation of biomolecular structure and dynamics at the atomic level, both in solutions and in solid state. The successful application of NMR in biology requires multidisciplinary approach combining knowledge in biochemistry, molecular biology, quantum physics, electronics, data analysis, and computational chemistry. The high-end instrumentation and the team of experienced researchers will ensure expert services, user training, and the cost-effective use of resources both for internal and external users. Benefits include access to state-of-the-art high-field NMR instrumentation and support in processing, analysis and interpretation of the experimental data. External user projects will be selected by peer review on the basis of scientific merit, technical suitability and feasibility. The centre will also offer training enabling non-specialists to develop the necessary skills.