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Canvax

Canvax is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country.

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Sites 1
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Small business

Agricultural Sciences Research & Development

  • DNA/Protein analysis Analyze DNA and proteins for allergens, pathogens and species identification.

Antibodies

  • Antibody Detection Quantitate, localize and visualize proteins and other antigens.
  • Antibody Protein De Novo Sequencing Sequence antibody proteins using multiple enzyme digestion and high-resolution LC-MS/MS.
  • Antibody Sequencing Sequence cDNA encoding variable heavy (VH) and variable light (VL) domains of a hybridoma cell line.
  • Antibody-Drug Conjugation Improve therapeutic properties of an antibody or drug by joining them together.
  • Epitope Mapping Map the antibody-antigen binding region to define protein-protein interaction sites.
  • Immunodetection Use antibodies to identify a protein or antigen.
Show all 9 in Antibodies 3 more
  • Polyclonal Antibody Production Generate polyclonal antibodies in vivo using evolutionary distant animal species.
  • Polyclonal/Monoclonal Antibody Production Generate polyclonal or monoclonal antibodies in a range of animal species, over-express antibodies in cultured cells.
  • Rabbit Monoclonal Antibody Development Develop monoclonal antibodies using rabbit as the host animal.

Biomarkers

  • Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
  • Customized Primary Cell Isolation Plan and execute the isolation of primary cells from a specific biosample.
  • Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
  • Human Primary Cell Isolation Isolate primary cells from various human tissues.
  • Lipid Kinase Assays Use biochemical, cell-based or in vivo assays to measure lipid kinase activity.
  • Microbiome Services Examine the community of commensal, symbiotic, and pathogenic microorganisms that make up the microbiome.
Show all 8 in Biomarkers 2 more
  • Single Cell quantitative Real Time-PCR Assess gene expression levels and patterns in a single cell.
  • Whole Transcriptome Amplification Amplify total RNA from a single cell.
Show all 82 services 69 more

Cell Culture and Characterization

  • Bacterial Cell Culture Culture and Grow bacterial cells.
  • Cell Culture Culture primary or immortalized cell lines.
  • Cell Transfection Produce, package and optimize transfection of your siRNA or DNA construct.
  • Recombinant Technology Manipulate genotypes to introduce or modify the expression of specific cell products or physical traits.
  • RNA-Based Transfection Deliver RNA to cells by microinjection, electroporation or lipid-mediated transfection.
  • Yeast Cell Culture Grow yeast strains or species.

Chemical and Compound Analysis

  • Endotoxin Testing Use standard assays like LAL (Limulus Amebocyte Lysate), rFC (Recombinant Factor C), or MAT (Monocyte Activation Test) to detect and quantify the level of endotoxins in a sample
  • Immunoaffinity Chromatography Use antibody-antigen interactions to isolate and concentrate analytes.
  • Size Exclusion Chromatography Separate and identify analytes based on their molecular size.
  • Structural Chemistry Examine the relationship between protein structure and function.

Chemistry, Manufacturing and Controls (CMC)

  • Lipoparticle Technology Capture conformationally intact membrane proteins directly from the cell surface using lipoparticle technology.

Discovery Chemistry

  • Compound Docking Identify potential compound hits based on the 3D structure of a target protein.
  • Discovery Computational Chemistry Model the interaction of a drug candidate with protein targets such as kinases, GPCRs, receptors, ion channels or enzymes.
  • Virtual Screening Use software algorithms to virtually screen millions of potential compounds and peptides for binding.

Disease Models

  • Microbiome-Based Skin Disease Technology Modify the skin microbiome and deliver therapeutic proteins to the target.
  • Non Obese Diabetic Mice Use a single animal species to create one or more disease models for diabetes.
  • Receptor Binding Models Measure the binding and distribution of drugs and biologics in animal tissues.

DNA & RNA

  • cDNA cloning & subcloning Move cDNA fragments between different cloning vectors.
  • cDNA library construction Generate a library of recombinant cDNA clones.
  • Cell Free DNA Assay Detect known mutations and discover new ones in cell-free plasma DNA.
  • CRISPR Using advanced CRISPR technology, add or delete base pairs at a specifically targeted DNA loci.
  • ddPCR-Based Plasma Genotyping Perform noninvasive tumor genotyping.
  • DNA Library Screening Screen genomic or cDNA libraries for positive clones.
Show all 21 in DNA & RNA 15 more
  • DNA Mutagenesis Introduce insertions, deletions and substitutions into DNA clones.
  • DNA Products Find DNA products including gDNA, cDNA clones, vectors and constructs from mice, insects, yeast, bacteria and viruses.
  • DNA Sequencing Determine the nucleotide sequence of DNA samples.
  • DNA Synthesis Produce DNA fragments for microarrays, PCR, cloning and expression studies.
  • Genome Editing Use CRISPR, ZFN, TALEN or AAV gene targeting for targeted gene mutations and creation of transgenics.
  • Genomic DNA Purification Isolate genomic DNA from cells or tissue samples.
  • Methylation Specific PCR Determine the methylation status of a CpG site without the need for base-specific endonucleases.
  • PCR Mutagenesis Use polymerase chain reaction to create mutations in a cloned gene.
  • Plasmid DNA Preparation and Extraction Prepare plasmid DNA starting from E. coli cell pellets, transformed colonies or DNA samples.
  • qPCR Analysis Measure the accumulation of PCR products in real time.
  • Quantitative RT PCR Use quantitative reverse transcription polymerase chain reaction to measure absolute and relative mRNA abundance.
  • RNA Amplification Produce RNA from pre-clinical and clinical samples for use in gene expression studies.
  • RNA Extraction Isolate total RNA or mRNA from cells or tissues
  • RNA Sequencing Use Next Generation Sequencing techniques to Identify RNA transcripts, examine differential expression patterns and analyze splice variants.
  • RNAi Pathway Analysis Use high-throughput RNAi genetic screens to elucidate relevant signaling pathways.

In Vitro ADME

  • Reference Standards Find reference standards for assays, tests and services.

In Vitro Assays

  • Biosensor Assays Evaluate biological activity of new compounds, detect toxic metabolites or monitor biomarkers.
  • ImmunoSEQ Assay Unmask the identity of millions of T- and B-cell receptors in a single sample using bias-controlled multiplex PCR amplification, high-throughput sequencing, and sophisticated bioinformatics.
  • Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
  • Virus Detection Assays Use ultra-sensitve methods to reliably detect low level viruses.

In Vitro Pharmacology

  • Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
  • G-Protein Coupled Receptor (GPCR) Assays Detect ligand binding, receptor dimerization and downstream signal transduction events.
  • High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
  • Kinase Assays Measure activity of over 500 kinases in biochemical or cell-based assays.
  • Oxidase Assays Use biochemical, cell-based or in vivo assays to measure oxidase activity.
  • Polymerase Assays Measure polymerase activity in biochemical and cell-based assays.
Show all 9 in In Vitro Pharmacology 3 more
  • Protease Assay Measure protease activity in biochemical and cell-based assays.
  • Target Identification Identify the target(s) of a biologically active substance.
  • Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.

In Vitro Toxicology

  • ADCC and CDC Assay Services Measure toxicity of antibodies.
  • Cytotoxicity Test for effects on cell viability and proliferation

Other Specialty Toxicology

  • Residual DNA Analysis Measure contaminants found in therapeutics like biologicals and biosimilars that are produced in cells.

Protein Sciences

  • Bacterial Expression Produce milligram, gram and kilogram amounts of proteins.
  • Large Scale Protein Production Produce large amounts of protein using fermentors, wave mixers, bioreactors, and large-scale purification workflows.
  • Mammalian Expression Express high yields of recombinant proteins, antibodies, virus, viral-subunit proteins and gene-therapy vectors.
  • Protein Expression Produce recombinant proteins in prokaryotic or eukaryotic systems.
  • Recombinant Proteins Use recombinant DNA to produce proteins in vivo or in vitro.
  • Virus Production Produce high titer viruses, viral expression vectors and vaccines.
Show all 7 in Protein Sciences 1 more
  • Yeast Expression Amplify eukaryotic proteins that contain post translational modifications.

Scientific Data Services

  • In Silico Metagenomics/Metatranscriptomics Data Analysis Use software to analyze genomic information from multiple environmental sources.
  • Microbiome Data Analysis Determine the population composition of a microbial community and analyze its contribution to human or animal health.

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • Spain Boecillo 1 site

Source: Scientist.com supplier network (site locations)

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Sources: Scientist.com supplier network.

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