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Aagami

Aagami is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country and 2 service areas.

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Sites 1
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Small business

Developmental and Reproductive Toxicology (DART)

  • Reproductive Toxicology Study adverse sexual function and fertility and examine teratogenicity of compounds.

Disease Models

  • Cataract Models Measure therapeutic endpoints in animal models of cataracts.
  • Comparative Pharmacology Compare drug responses across species for improved reliability in translational studies.
  • Cough Models Test the therapeutic efficacy of drug candidates in cough models.
  • Cyp2f2 Knockout Mouse Study Cyp2f2-mediated lung metabolism.
  • Diabetic Retinopathy Models Assess therapeutic efficacy of drug candidates in diabetic retinopathy models of disease.
  • Drug-Induced Liver Injury (DILI) Toxicity Assays Use biochemical, cell-based or in vivo assays to measure toxicity from drug-induced liver injury.
Show all 23 in Disease Models 17 more
  • Dry Eye Models Measure therapeutic endpoints such as tear induction, TBUT, Schirmer strips (tear volume) and cornea staining.
  • In Vivo Physiologic Monitoring Monitor and collect data from conscious, freely moving laboratory animals.
  • In Vivo Technologies Models Carry out EEGs, cognition assessment, microdialysis, electrophysiology, MRI, ultrasound and tomographic analysis.
  • LPS Lung Inflammation Models Measure therapeutic endpoints in animal models of inflammation.
  • Macular Degeneration Models Use a single animal species to create one or more models for eye disease.
  • Microdialysis Models Measure the effect of drug candidates on neurotransmission in rat or mouse models.
  • Microsurgery in Rodents Outsource microsurgeries projects required for testing new therapies on a rodent model.
  • Obstructive Sleep Apnea Rat Study pathologic cardiac changes of obstructive sleep apnea (OSA) in a rat model.
  • Ocular Inflammation Models Measure ocular inflammation in models of eye disorders such as uveitis and keratitis.
  • Ophthalmic Models Test drug candidates in glaucoma, macular degeneration, keratitis, uveitis and CMV retinitis models.
  • OVA Lung Inflammation Models Measure therapeutic endpoints in animal models of inflammation.
  • Pigmented Rabbit Use a single animal species to create one or more disease models for eye cancer.
  • Precision Cut Lung Slices (PCLS) Use a phenotypically accurate model of lung behavior for screening and target validation.
  • Pulmonary Fibrosis Models Measure therapeutic endpoints in animal models of pulmonary fibrosis.
  • Receptor Binding Models Measure the binding and distribution of drugs and biologics in animal tissues.
  • Receptor Occupancy Models Determine the effective dose and concentration needed to reach effective levels in a given tissue.
  • Respiratory Models Test therapeutic efficacy of drug candidate in respiratory disease model.

Drug Development

  • Safety Pharmacology Consulting Consulting services that help with the detection of potential undesirable pharmacodynamic effects of chemical entities on physiological functions.

Environmental Assessment

  • Digital Vivarium® Platform Monitor and record a range of animal metrics by applying sensors and monitoring technology to animal cages.

General in vivo Toxicology

  • General Toxicology Use in vivo models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.
  • Mammalian Toxicology Use toxicity testing models to carry out required FDA or REACH safety testing.

Human Biological Samples

  • 3D InSight™ Liver Microtissues Perform in vitro assessment of islet function for efficacy and toxicity testing.
Show all 55 services 43 more

In Vitro Pharmacology

  • In Vitro Eye Models Measure cytokine production, cell viability, apoptosis and wound healing.
  • In Vitro Hemolysis Assay Evaluate the toxicity of a drug, metabolite or excipient by hemolytic release of hemoglobin in the plasma.
  • In Vitro Hepatotoxicity Assays Use in vitro assays to measure hepatoxicity-related activities.
  • In Vitro Oncology Models Use cell-based and biochemical models of cancer.

Model Development

  • Juvenile Toxicology Assess developmental and reproductive defects due to neurobehavioral, skeletal and muscle growth effects.
  • Pulmonary Hypertension Animal Model Study the pathology of pulmonary arterial hypertension (PAH) and investigate potential therapies.
  • Zucker Rat Use a single animal species to create one or more disease models for cachexia.

Other Specialty Toxicology

  • Phototoxicity Determine whether drug treatment causes light-activated toxic effects.

Safety Pharmacology

  • Abuse Liability Determine the dependence potential of a therapeutic.
  • CNS Behavioral Measure safety toxicology effects of CNS and behavioral drugs.
  • Endocrine Disruptor Screening Use biochemical, cell based or in vivo assays to identify and quantify endocrine-modulating agents.
  • Immunotoxicity Measure effects of drugs on immune function, allergic hypersensitization and autoimmune toxicity.
  • Microelectrode Array Neurotoxicity Assays Use microelectrode array to measure neurotoxicity-related activities.
  • Off Target Effects Assess toxicities by body weight, clinical chemistry, hematology, urinalysis and terminal necropsy and pathology.
Show all 11 in Safety Pharmacology 5 more
  • Respiratory Toxicology Assess difficulty breathing, altered respiration, blood gas changes and blood pH issues due to adverse reactions.
  • Safety Pharmacology Assess the impact of a therapeutic for human use on vital organ systems before first-in-man drug testing.
  • Target Safety Assessment Understand the role of your drug target and assess risks in normal physiology.
  • Telemetry Use implantable or external devices to study physiological parameters in model organisms
  • Tissue Cross Reactivity Assess the toxic effects of humanized monoclonal antibodies in 33 normal types recommended by the FDA.

Specialty Dosing Routes

  • Dermal Toxicology Assess toxicity in rodent dermal testing models.
  • Inhalation Toxicology Measure toxicity by daily clinical observation, body weight, clinical chemistry, hematology, and terminal necropsy and pathology.
  • Ophthalmologic Toxicology Measure toxicity by microscopy, vitrectomy, tonometry, electroretionography and corneal colorimetry.

Target Animal and Human Food Safety

  • Toxicokinetic Analysis Determine the drug concentration at which off-target or toxic effects occur.

Other services

  • Human Small Airway-On-a-Chip Study human lung inflammation and drug responses in vitro.
  • Implantable Telemetry for Large Animals Use implantable telemetry to study physiological parameters in large animals, such as dogs, primates, swine, sheep, horses, and cattle among others.
  • In Vivo Hollow Fiber Assay Evaluate test items concurrently with three different tumor cell lines within the same mouse.

Service areas:

Toxicology Chemistry

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • United States Naperville 1 site

Source: Scientist.com supplier network (site locations)

About this supplier

In the supplier's own words, as listed in the Scientist.com network.

Aagami provides rodent toxicology (GLP), organic and inorganic synthesis and API synthesis.

Website
www.aagami.net

Source: Scientist.com supplier network, written by the supplier

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Sources: Scientist.com supplier network.

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