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Aagami
Aagami is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country and 2 service areas.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Developmental and Reproductive Toxicology (DART)
- Reproductive Toxicology Study adverse sexual function and fertility and examine teratogenicity of compounds.
Disease Models
- Cataract Models Measure therapeutic endpoints in animal models of cataracts.
- Comparative Pharmacology Compare drug responses across species for improved reliability in translational studies.
- Cough Models Test the therapeutic efficacy of drug candidates in cough models.
- Cyp2f2 Knockout Mouse Study Cyp2f2-mediated lung metabolism.
- Diabetic Retinopathy Models Assess therapeutic efficacy of drug candidates in diabetic retinopathy models of disease.
- Drug-Induced Liver Injury (DILI) Toxicity Assays Use biochemical, cell-based or in vivo assays to measure toxicity from drug-induced liver injury.
Show all 23 in Disease Models
- Dry Eye Models Measure therapeutic endpoints such as tear induction, TBUT, Schirmer strips (tear volume) and cornea staining.
- In Vivo Physiologic Monitoring Monitor and collect data from conscious, freely moving laboratory animals.
- In Vivo Technologies Models Carry out EEGs, cognition assessment, microdialysis, electrophysiology, MRI, ultrasound and tomographic analysis.
- LPS Lung Inflammation Models Measure therapeutic endpoints in animal models of inflammation.
- Macular Degeneration Models Use a single animal species to create one or more models for eye disease.
- Microdialysis Models Measure the effect of drug candidates on neurotransmission in rat or mouse models.
- Microsurgery in Rodents Outsource microsurgeries projects required for testing new therapies on a rodent model.
- Obstructive Sleep Apnea Rat Study pathologic cardiac changes of obstructive sleep apnea (OSA) in a rat model.
- Ocular Inflammation Models Measure ocular inflammation in models of eye disorders such as uveitis and keratitis.
- Ophthalmic Models Test drug candidates in glaucoma, macular degeneration, keratitis, uveitis and CMV retinitis models.
- OVA Lung Inflammation Models Measure therapeutic endpoints in animal models of inflammation.
- Pigmented Rabbit Use a single animal species to create one or more disease models for eye cancer.
- Precision Cut Lung Slices (PCLS) Use a phenotypically accurate model of lung behavior for screening and target validation.
- Pulmonary Fibrosis Models Measure therapeutic endpoints in animal models of pulmonary fibrosis.
- Receptor Binding Models Measure the binding and distribution of drugs and biologics in animal tissues.
- Receptor Occupancy Models Determine the effective dose and concentration needed to reach effective levels in a given tissue.
- Respiratory Models Test therapeutic efficacy of drug candidate in respiratory disease model.
Drug Development
- Safety Pharmacology Consulting Consulting services that help with the detection of potential undesirable pharmacodynamic effects of chemical entities on physiological functions.
Environmental Assessment
- Digital Vivarium® Platform Monitor and record a range of animal metrics by applying sensors and monitoring technology to animal cages.
General in vivo Toxicology
- General Toxicology Use in vivo models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.
- Mammalian Toxicology Use toxicity testing models to carry out required FDA or REACH safety testing.
Human Biological Samples
- 3D InSight™ Liver Microtissues Perform in vitro assessment of islet function for efficacy and toxicity testing.
Show all 55 services
In Vitro Pharmacology
- In Vitro Eye Models Measure cytokine production, cell viability, apoptosis and wound healing.
- In Vitro Hemolysis Assay Evaluate the toxicity of a drug, metabolite or excipient by hemolytic release of hemoglobin in the plasma.
- In Vitro Hepatotoxicity Assays Use in vitro assays to measure hepatoxicity-related activities.
- In Vitro Oncology Models Use cell-based and biochemical models of cancer.
Model Development
- Juvenile Toxicology Assess developmental and reproductive defects due to neurobehavioral, skeletal and muscle growth effects.
- Pulmonary Hypertension Animal Model Study the pathology of pulmonary arterial hypertension (PAH) and investigate potential therapies.
- Zucker Rat Use a single animal species to create one or more disease models for cachexia.
Other Specialty Toxicology
- Phototoxicity Determine whether drug treatment causes light-activated toxic effects.
Safety Pharmacology
- Abuse Liability Determine the dependence potential of a therapeutic.
- CNS Behavioral Measure safety toxicology effects of CNS and behavioral drugs.
- Endocrine Disruptor Screening Use biochemical, cell based or in vivo assays to identify and quantify endocrine-modulating agents.
- Immunotoxicity Measure effects of drugs on immune function, allergic hypersensitization and autoimmune toxicity.
- Microelectrode Array Neurotoxicity Assays Use microelectrode array to measure neurotoxicity-related activities.
- Off Target Effects Assess toxicities by body weight, clinical chemistry, hematology, urinalysis and terminal necropsy and pathology.
Show all 11 in Safety Pharmacology
- Respiratory Toxicology Assess difficulty breathing, altered respiration, blood gas changes and blood pH issues due to adverse reactions.
- Safety Pharmacology Assess the impact of a therapeutic for human use on vital organ systems before first-in-man drug testing.
- Target Safety Assessment Understand the role of your drug target and assess risks in normal physiology.
- Telemetry Use implantable or external devices to study physiological parameters in model organisms
- Tissue Cross Reactivity Assess the toxic effects of humanized monoclonal antibodies in 33 normal types recommended by the FDA.
Specialty Dosing Routes
- Dermal Toxicology Assess toxicity in rodent dermal testing models.
- Inhalation Toxicology Measure toxicity by daily clinical observation, body weight, clinical chemistry, hematology, and terminal necropsy and pathology.
- Ophthalmologic Toxicology Measure toxicity by microscopy, vitrectomy, tonometry, electroretionography and corneal colorimetry.
Target Animal and Human Food Safety
- Toxicokinetic Analysis Determine the drug concentration at which off-target or toxic effects occur.
Other services
- Human Small Airway-On-a-Chip Study human lung inflammation and drug responses in vitro.
- Implantable Telemetry for Large Animals Use implantable telemetry to study physiological parameters in large animals, such as dogs, primates, swine, sheep, horses, and cattle among others.
- In Vivo Hollow Fiber Assay Evaluate test items concurrently with three different tumor cell lines within the same mouse.
Service areas:
Where it operates
Sites by country, with the cities in each.
-
United States 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Aagami provides rodent toxicology (GLP), organic and inorganic synthesis and API synthesis.
- Website
- www.aagami.net
Work with Aagami on Scientist.com
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