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ImQuest BioSciences
ImQuest BioSciences is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country and 2 service areas.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Biomarkers
- Antimicrobial Effectiveness Testing Measure the efficacy of anti-microbial preservatives added to a product.
- Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
- Colony Forming Cell Assay Examine ability of hematopoietic stem cells to form colonies in vitro.
- Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
- Immunophenotyping Separate cell types based on their expression of biomarkers or based on their individual and unique expression patterns.
- Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
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- Plaque Assays Determine infectious viral titer using plaque-forming units or purify viral stocks.
Cell Culture and Characterization
- Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
- Bacterial Cell Culture Culture and Grow bacterial cells.
- Cell Culture Culture primary or immortalized cell lines.
- RNA-Based Transfection Deliver RNA to cells by microinjection, electroporation or lipid-mediated transfection.
Chemical and Compound Analysis
- Dissolution Profiling Measure release of API from formulation (tablet or capsules) under GMP guidelines.
- Excipient Compatibility Test excipients for drug formulation, effects of temperature, time, humidity, pH and light exposure as well as excipient release.
- Liquid Chromatography Separate substances using a mobile and stationary phase.
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Chemistry, Manufacturing and Controls (CMC)
- Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
- Drug Product Stability Use accelerated stress conditions to determine degradation pathways and identify manufacturing issues.
- Forced Degradation Run light, heat, humidity, acid hydrolysis and oxidation tests to evaluate substance degradation.
Clinical Consulting
- Cell Services Consulting Whether you are an experienced drug hunter working in the pharmaceutical industry or an academic researcher looking to submit g...
Disease Models
- Bacterial Infection Models Measure therapeutic endpoints in animal models of bacterial infection.
- Hepatitis B Virus Models Measure therapeutic endpoints in animal models of Hepatitis B virus infection.
- Hepatitis C Virus Models Measure therapeutic endpoints in animal models of Hepatitis C virus infection.
- Infectious Disease Models Test therapeutic efficacy of drug candidate in infectious disease model.
- Osteoporosis Models Measure therapeutic endpoints in animal models of osteoporosis.
- Viral Infection Models Measure therapeutic endpoints in animal models of viral infection.
DNA & RNA
- Amplicon 16s rRNA Sequencing Identify and compare bacteria present within a given sample.
- DNA Mutagenesis Introduce insertions, deletions and substitutions into DNA clones.
- Genotyping Examine a DNA sequence to identify specific genetic varients .
- PCR Mutagenesis Use polymerase chain reaction to create mutations in a cloned gene.
- qPCR Analysis Measure the accumulation of PCR products in real time.
- Target Gene Expression Measure expression of a target gene at the protein, RNA and DNA level.
Show all 7 in DNA & RNA
- Whole Genome Amplification (WGA) Amplify an entire genome from a single cell.
Drug Development
- Assay Development Consulting Request consultant services measuring the activity of a drug or biochemical in an organism or organic sample.
In Vitro Assays
- Annexin V Apoptosis Assay Detect and quantify apoptotic cells based on loss of membrane asymmetry.
- Antivirals Measure anti-viral activity in biochemical and cell assays.
- Assay Development Construct or create new assays or modify existing ones.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Cell Based Assays Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
- ELISpot Assay and Testing Detect low levels of antigens.
Show all 10 in In Vitro Assays
- Endpoint Dilution Assay (TCID50) Assay Determine the viral titer to induce cell death in half the cell population of an inoculated tissue culture.
- Microbiology Study microbes and their role in human health.
- Pathway Mapping Define mechanisms of action by analyzing protein pathways affected by drug treatment.
- Phenotype Assays Measure effects of drug candidate on the morphology or function of cells and whole animals.
In Vitro Pharmacology
- Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
- High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
- Immuno-oncology Assays Use biochemical, cell based or in vivo assays to measure the activity of immuno-therapy targets.
- In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
- PARP Assays Use biochemical, cell-based or in vivo assays to measure PARP activity.
- Protease Assay Measure protease activity in biochemical and cell-based assays.
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- Protein Targets Protein Targets are of pharmaceutical interest for drug discovery purposes.
In Vitro Toxicology
- Cardiomyocyte Toxicity Assess cytotoxic effects of pre-clinical compounds on cardiomyocytes.
- Cytotoxicity Test for effects on cell viability and proliferation
- Hematopoietic Cell Toxicity Examine cytotoxic effects of pre-clinical compounds or biologics on adult stem cells.
- HepaRG Cells Obtain terminally differentiated and cryopreserved hepatic cells that retain many characteristics of primary human hepatocytes.
- Hepatocyte Toxicity Assess the cytotoxic effects of pre-clinical compounds on hepatocytes purified from patients and animal models.
Other Specialty Toxicology
- Viral Testing Characterize viral products for functional activity and possible contamination.
Product Orders
- BioTx General Biotherapeutics analyze therapeutics and drugs via biological means and recombinant DNA. Pre-clinical sample bioanalysis and le...
Protein Sciences
- ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
Testing Services
- Accelerated Stability Determine shelf life of drug formulations by comparing API breakdown at elevated temperature.
- Freeze-Thaw Testing Use freeze-thaw cycling to measure the long-term durability of cosumer products.
Other services
- New Request
Service areas:
Where it operates
Sites by country, with the cities in each.
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United States 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
p<>. ImQuest BioSciences aims to be the leading international provider of preclinical research and development services for small molecule, biologic, and vaccine products for the treatment and prevention of infectious disease and cancer. p<>. Using state of the art and established in vitro models, ImQuest rapidly identifies therapeutic agents with the potential to inhibit the replication of infectious agents. Cell-based and biochemical assays are designed to define the precise mode of action of the test agent and to compare the activity of novel molecules to existing approved therapeutics...
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p<>. ImQuest BioSciences aims to be the leading international provider of preclinical research and development services for small molecule, biologic, and vaccine products for the treatment and prevention of infectious disease and cancer.
p<>. Using state of the art and established in vitro models, ImQuest rapidly identifies therapeutic agents with the potential to inhibit the replication of infectious agents. Cell-based and biochemical assays are designed to define the precise mode of action of the test agent and to compare the activity of novel molecules to existing approved therapeutics. A wide variety of secondary assays are utilized to determine the test agent’s range of action. Combination therapy, as well as drug resistant virus selection and characterization, is performed to confirm the clinical potential of the agent.
- Website
- imquestbio.com
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