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Lazarus Biosciences
Lazarus Biosciences is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country.
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1
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Bioimaging
- Bioimaging Visualize biological process non-invasively in real time.
- Confocal/Optical Microscopy Use optical imaging technique to increase optical resolution and contrast of a micrograph.
- Microscopy Use microscopy to analyze surfaces of biological materials and to develop 3D images of biological structures.
- Single Molecule Localization Microscopy Enable structural resolution of biological samples at the nanometer range using light in the visible spectrum.
- Super Resolution Microscopy Utilize fluorescence microscopy and super-resolution techniques including STED, SIM, SMLM, and/or STORM to directly observe living subcellular structures and activities.
Biomarkers
- Basic Metabolic Profiling Set up assays that monitor drug metabolite formation after administration of drug to an animal model or patient.
- Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
- Metabolomics Biomarker Discovery Identify and quantitate metabolite biomarkers in blood, urine, CSF and bodily fluids.
- Molecular Profiling Modify genome activity without changing the DNA sequence.
- Multi-Omics Study Use an integrated multi-omics study to understand a disease mechanism.
- Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Data Science/Bioinformatics
- Discovery Compound Screening Analytics Screening of an entire compound library directly against the drug target or in a more complex assay.
- Discovery Data Analysis Analysis that helps you make sense of your discovery data
- Discovery Databases Databases specifically designed for drug discovery use.
- Discovery Omics Analytics A process to analyze various omics data (genomics, transcriptomics, proteomics, metabolomics, etc.) This can include the integration of different omics data. Helps to better understand the molecular environment...
- Discovery Software Tools Software designed to serve the needs of discovery research groups.
Show all 56 services
In Vitro ADME
- Drug Drug Interactions Determine whether a substance affects the activity of a drug when both are administered together.
- HT ADME (High-Throughput Absorption, Distribution, Metabolism and Excretion) Analyze the process and effects of a chemical that is ingested by an organism using an advanced technological screening process. Use for drug...
- In Vitro ADME in Vitro ADME services
- Metabolic Stability Measure metabolic vulnerability to drug metabolizing enzymes using cell-free, cell-based and in vivo assays.
- Metabolite Identification Identify drug metabolites that are formed after administration of drug to an animal model or patient.
- Metabolite Identification and Profiling Estimate drug candidate metabolites after administration of drug to an animal or human subject.
Show all 8 in In Vitro ADME
- Metabolite Quantification Quantify drug metabolites formed after drug administration to an animal model or patient.
- Reactive Metabolite Ensure that your drug candidate is not generating toxic reactive metabolites in vivo.
In Vitro Assays
- 3D Cell Microscopy Assay Investigate cellular and subcellular events in three dimensional 3D cultures by using fluorescence microscopy.
- 3Screen™ 3D In Vitro Services 3Screen™ Platform enables complete 3D cell culture characterization.
- Biosensor Assays Evaluate biological activity of new compounds, detect toxic metabolites or monitor biomarkers.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Cell Based Assays Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
- Cell Painting Cell painting is multiplexed image-based assay used to investigate subtle changes in cellular homeostasis
Show all 15 in In Vitro Assays
- Cell-based Screening Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Fully Automated Assays Develop and perform assays that require no manual steps
- High Content Screening Analyze whole cells or components of cells with simultaneous readout of several parameters.
- HTS Assay Development Develop assays to use in high throughput screening.
- In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
- In Vitro Efficacy Test Use in vitro models to test the efficacy of your products.
- In Vitro Human Cell Assays Request in vitro human cells for assays
- Phenotype Assays Measure effects of drug candidate on the morphology or function of cells and whole animals.
- Reactive Species Assays Use biochemical, cell-based or in vivo assays to detect and evaluate the effects of reactive species.
In Vitro Pharmacology
- Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
- High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
- In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
In Vitro Toxicology
- Cardiomyocyte Toxicity Assess cytotoxic effects of pre-clinical compounds on cardiomyocytes.
- Cardiotoxicity Evaluate the effect of a compound on heart electrophysiology and muscle function.
- Cytotoxicity Test for effects on cell viability and proliferation
- Cytotoxicity Testing Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.
- Endothelial Cell Toxicity Assess the cytotoxic effects of pre-clinical compounds on the vascular system.
- Hepatocyte Toxicity Assess the cytotoxic effects of pre-clinical compounds on hepatocytes purified from patients and animal models.
Protein Sciences
- Peptide Discovery Identifying and developing new peptides.
REACH Services
- In Vitro REACH Services Perform skin or eye irriation tests, sensitivily and geneotoxicity tests
Safety Pharmacology
- Neurotoxicity Study Study of the adverse effects of a substance on the brain or peripheral nervous system.
Scientific Data Services
- Data Curation Organize and integrate data collected from various sources to ease data discovery and retrieval.
- Data Infrastructure Design and deploy an information management solution suited to users' specific needs.
- Database Integration Convert bioinformatics results from multiple data sources (DSs) into a single operational format.
- Metabolomics Data Analysis Use metabolites to identify any potential biomarkers or novel therapeutic targets that may play a role in the mechanisms responsible for the progression of a disease.
Testing Services
- In Vitro Toxicology Testing Non-animal testing employing US and international methodologies for determining irritation and other undesirable potentials.
- Website
- www.lazarusbiosciences.com
Where it operates
Sites by country, with the cities in each.
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Ireland 1 site
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