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Research supplier
SARomics Biostructures
SARomics Biostructures is listed as a small business research supplier in the Scientist.com network, with 3 sites in 2 countries and 1 service area.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Antibodies
- Antibody Purification Purify multiple antibody types including IgG, IgM, IgA and IgY.
- Epitope Mapping Map the antibody-antigen binding region to define protein-protein interaction sites.
Chemical and Compound Analysis
- Analytical Separations and Purification Analytical Separation and Purification of compound/molecule.
- Circular Dichroism Examine the secondary structure and folding properties of proteins in solution.
- Dynamic Light Scattering Determine the size of particles and extent of molecular aggregation in a suspension.
- Ion Exchange Chromatography Separate and detect analytes.
- Isothermal Titration Calorimetry An ITC assay will be established and optimised for the affinity measurement of test substance to target molecule.
- NMR Structure Determine molecular structure, identify chemical impurities and validate sample integrity.
Show all 14 in Chemical and Compound Analysis
- Protein Crystallization Create high quality protein-ligand crystals for x-ray diffraction studies.
- Protein Melting Point Analysis Assess protein stability by Differential Scanning Calorimetry (DSC) or Fluorimetry (Thermofluor) methods.
- Protein Separation and Detection Separate proteins based on properties such as solubility, adsorption or size differences.
- Protein Structure Determine the three dimensional structure of a protein by NMR or x-ray crystallography.
- Size Exclusion Chromatography Separate and identify analytes based on their molecular size.
- Solution Nuclear Magnetic Resonance Identify molecular structure or impurities and assess product integrity of solution samples.
- Structural Chemistry Examine the relationship between protein structure and function.
- Structural Elucidation Determine chemical structure of a compound. Characterization techniques include mass spectrometry, infrared spectroscopy and X-ray crystallography.
Chemistry, Manufacturing and Controls (CMC)
- Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
Data Science/Bioinformatics
- In Silico Drug-Drug Interactions Use computational tools to predict pharmaceutical, pharmacodynamic or pharmacokinetic drug-drug interactions to maximize drug regimen safety.
Discovery Chemistry
- Compound Docking Identify potential compound hits based on the 3D structure of a target protein.
- Discovery Computational Chemistry Model the interaction of a drug candidate with protein targets such as kinases, GPCRs, receptors, ion channels or enzymes.
- Fragment Libraries Find fragment libraries for screening against a protein or cellular target.
- In Silico Lead Optimization Use in silico design to enhance the ADME-PK properties of candidate drugs to maximize efficacy and safety.
- Library Design & Evaluation Use structural knowledge to design target-focused compound libraries for screening.
- Pharmacophore Modeling Use computer models to identify hits based on structural similarity to known active compounds.
Show all 9 in Discovery Chemistry
- QSAR Analysis Develop quantitative structure–activity relationship models for drug design.
- Structure Activity Relationship (SAR) Analyze the relationship between the structure of a compound and its biological activity.
- Virtual Screening Use software algorithms to virtually screen millions of potential compounds and peptides for binding.
Show all 43 services
Protein Sciences
- Affinity Tag Purification Purify proteins under physiological conditions at their native cellular levels.
- Bacterial Expression Produce milligram, gram and kilogram amounts of proteins.
- Insect Expression Use baculovirus infected cells or non-lytic cell systems to produce glycosylated proteins.
- Mammalian Expression Express high yields of recombinant proteins, antibodies, virus, viral-subunit proteins and gene-therapy vectors.
- Native Protein Purification Purify native proteins from sources such as tissue & serum.
- NMR Determine molecular and protein structure, and validate sample integrity.
Show all 15 in Protein Sciences
- Peptide/Protein Products Purchase off-the-shelf protein or peptide products.
- Protein Binding Determine drug-protein binding interactions
- Protein Expression Produce recombinant proteins in prokaryotic or eukaryotic systems.
- Protein Interaction Measure the interaction of a protein to other macromolecules or peptide ligands.
- Protein Production Produce recombinant protein molecules in prokaryotic or eukaryotic systems.
- Protein Purification Isolate native or recombinant proteins from a sample.
- Protein Services Consulting Expert advice to evaluate and analyze protein function and expression.
- Recombinant Proteins Use recombinant DNA to produce proteins in vivo or in vitro.
- X-Ray Crystallography Elucidate structures of biological macromolecules such as proteins and nucleic acids.
Other services
- New Request
Service areas:
Where it operates
Sites by country, with the cities in each.
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Sweden 2 sites
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United States 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
SARomics Biostructures is the leading Scandinavian provider of structural biology and in silico drug discovery services. The company accelerates its customers’ drug discovery processes by providing structure-based drug design support including protein crystallization, X-ray protein structure determination, computational chemistry, protein modeling and NMR spectroscopy analyses. Our services also include biophysics-based fragment screening, fragment-based lead discovery and protein modeling using our proprietary ProPHECY™ technology. The company is equipped with state-of-the-art robotics...
Show the full description
SARomics Biostructures is the leading Scandinavian provider of structural biology and in silico drug discovery services. The company accelerates its customers’ drug discovery processes by providing structure-based drug design support including protein crystallization, X-ray protein structure determination, computational chemistry, protein modeling and NMR spectroscopy analyses. Our services also include biophysics-based fragment screening, fragment-based lead discovery and protein modeling using our proprietary ProPHECY™ technology. The company is equipped with state-of-the-art robotics for low volume high-throughput crystallization and X-ray diffraction experiments. Its strategic location close to the MAX-lab synchrotron radiation facility provides the company with instant access to beamlines.
Please read more at: www.saromics.com
- Professional associations
- ACS
- Website
- www.saromics.com
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