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Biodextris
Biodextris is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Antibodies
- Antibody Detection Quantitate, localize and visualize proteins and other antigens.
- Antibody Purification Purify multiple antibody types including IgG, IgM, IgA and IgY.
- Polyclonal/Monoclonal Antibody Production Generate polyclonal or monoclonal antibodies in a range of animal species, over-express antibodies in cultured cells.
Cell Culture and Characterization
- Bacterial Cell Culture Culture and Grow bacterial cells.
- Cell Culture Culture primary or immortalized cell lines.
- Spent Media Analysis Measure chemical alterations, such as variations in amino acids, glucose, contaminants, and metabolites, in a cell culture medium throughout the culturing process.
- Yeast Cell Culture Grow yeast strains or species.
Chemical and Compound Analysis
- Analytical Separations and Purification Analytical Separation and Purification of compound/molecule.
- Dynamic Light Scattering Determine the size of particles and extent of molecular aggregation in a suspension.
- Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
- Endotoxin Testing Use standard assays like LAL (Limulus Amebocyte Lysate), rFC (Recombinant Factor C), or MAT (Monocyte Activation Test) to detect and quantify the level of endotoxins in a sample
- Excipient Compatibility Test excipients for drug formulation, effects of temperature, time, humidity, pH and light exposure as well as excipient release.
- Immunoaffinity Chromatography Use antibody-antigen interactions to isolate and concentrate analytes.
Show all 16 in Chemical and Compound Analysis
- Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) Analysis Detect metals and several non-metals at concentrations as low as one part in 1015 (part per quadrillion, ppq) on non-interfered low-background isotopes.
- Ion Exchange Chromatography Separate and detect analytes.
- Liquid Chromatography Separate substances using a mobile and stationary phase.
- Particle Size Analysis Measure particle size distribution and characterize particle size, porosity and composition.
- Photostability Measure drug degradation rates after exposure to various light sources.
- Process Residual Impurities Detection Measure trace levels of impurities.
- Protein Separation and Detection Separate proteins based on properties such as solubility, adsorption or size differences.
- Size Exclusion Chromatography Separate and identify analytes based on their molecular size.
- Static Light Scattering Use scattered light intensity to determine the average molecular weight of biopolymers.
- UV-Spectroscopy Conduct sample analysis based on light absorption and transmission.
Show all 48 services
Chemical and Compound Testing
- Product Testing Ensure product quality standards are met.
Chemistry, Manufacturing and Controls (CMC)
- API and Drug Product Stability Testing API and Drug Product Stability Testing.
- Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
- Drug Formulation Combine substances including the active drug into a final product with the desired metabolic and therapeutic properties.
- Forced Degradation Run light, heat, humidity, acid hydrolysis and oxidation tests to evaluate substance degradation.
Discovery Chemistry
- LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
In Vitro Assays
- Assay Development Construct or create new assays or modify existing ones.
Protein Sciences
- Affinity Tag Purification Purify proteins under physiological conditions at their native cellular levels.
- Bacterial Expression Produce milligram, gram and kilogram amounts of proteins.
- ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
- Immunoprecipitation Precipitate a protein of interest out of solution using an antibody to which it binds.
- Large Scale Protein Production Produce large amounts of protein using fermentors, wave mixers, bioreactors, and large-scale purification workflows.
- Mammalian Expression Express high yields of recombinant proteins, antibodies, virus, viral-subunit proteins and gene-therapy vectors.
Show all 16 in Protein Sciences
- Native Protein Purification Purify native proteins from sources such as tissue & serum.
- Peptide/Protein Based Vaccine Production Create a peptide or protein antigen for use in artificial immunization.
- Protein Expression Produce recombinant proteins in prokaryotic or eukaryotic systems.
- Protein Identification Uncover or confirm the identity of a protein.
- Protein Production Produce recombinant protein molecules in prokaryotic or eukaryotic systems.
- Protein Purification Isolate native or recombinant proteins from a sample.
- Quantitative MS Quantify small and large molecules in the pg/ml range
- Recombinant Proteins Use recombinant DNA to produce proteins in vivo or in vitro.
- Western Blots Detect specific proteins in a sample of tissue homogenate or extract.
- Yeast Expression Amplify eukaryotic proteins that contain post translational modifications.
Testing Services
- Accelerated Stability Determine shelf life of drug formulations by comparing API breakdown at elevated temperature.
- Elevated Temperature Stability Determine the stability of a product at elevated temperature.
Where it operates
Sites by country, with the cities in each.
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Canada 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
BioDextris is comprised of product development scientists from the GSK Vaccines R&D center located in Laval (Montreal) Quebec. In mid-2015, we will offer process development, analytical development, protein design and small scale manufacturing of proteins. Consulting services in these areas will also be available. Our group has worked together within mid-sized and multi-national organizations since 2002. During this period we have developed dozens of products for early phase clinical trials conducted in the US, Canada and Europe. Our staff is familiar with regulatory aspects of technical...
Show the full description
BioDextris is comprised of product development scientists from the GSK Vaccines R&D center located in Laval (Montreal) Quebec. In mid-2015, we will offer process development, analytical development, protein design and small scale manufacturing of proteins. Consulting services in these areas will also be available.
Our group has worked together within mid-sized and multi-national organizations since 2002. During this period we have developed dozens of products for early phase clinical trials conducted in the US, Canada and Europe. Our staff is familiar with regulatory aspects of technical development as well as developing processes for complex biologic product development.
Our goal is to provide clients with product development services which will benefit from our technical knowledge and emphasis on quality.
- Website
- biodextris.com
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