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Digital BioPharm

Digital BioPharm is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country and 1 service area.

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Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 2
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Small business

Chemistry, Manufacturing and Controls (CMC)

  • Bulk Raw Materials Acquire raw materials in large volumes at wholesale pricing.
  • Excipients Acquire synthetic or natural inert components to formulate therapeutic agents.

Data Science/Bioinformatics

  • Discovery Statistical and Mathematical Modeling Use mathematical variables and equations to establish relationships between data.
  • In Silico ADME-PK Consultation Consult with experts for ADME-PK data analysis or predictive modelling design in different in vivo or in vitro states.
  • In Silico ADME-PK Predictions Use computer software to simulate in vivo physiological conditions of animals or humans to predict ADME-PK properties.
  • In Silico Cancer Genomics/Cancer Transcriptomics Analysis Interpret DNA sequencing and microarray data for cancer studies.
  • In Silico Drug-Drug Interactions Use computational tools to predict pharmaceutical, pharmacodynamic or pharmacokinetic drug-drug interactions to maximize drug regimen safety.
  • In Silico Epigenetic Compound Library Screening Use computer-aided methods to discover new compounds against key regulators of epigenetic signaling.
Show all 11 in Data Science/Bioinformatics 5 more
  • In Silico Nucleic Acid Microarray Analysis Use software to visualize and evaluate gene activity in response to various stimuli.
  • In Silico Pro-drug Predictions Use computer simulation to assess pro-drug absorption and conversion to predict pharmacokinetic properties.
  • In Silico Protein Microarray Analysis Use software to visualize and evaluate protein function and expression on a large scale.
  • In Silico Protein Modification Analysis Use computational methods to predict the behavior of modified proteins.
  • In Silico Protein Sequence Analysis Use software to predict protein structural and functional features and secondary structure components.

Discovery Chemistry

  • Activity Prediction Identify possible chemical hits based on the known three-dimensional structure of a protein.
  • Building Blocks Find chemicals used for creating new compound chemotypes and HTS libraries.
  • Certified Standards Find certified standards for assays, tests and services.
  • Compound Docking Identify potential compound hits based on the 3D structure of a target protein.
  • Compound Management Buy, maintain and process compound libraries, natural product libraries and building blocks.
  • Compound Purchase Buy compounds, building blocks or compound libraries.
Show all 25 in Discovery Chemistry 19 more
  • Compound Purchase Consulting Buy compounds, building blocks or compound libraries.
  • Compound Synthesis Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
  • Compound Synthesis Services (IP-sensitive) Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
  • Custom Building Blocks Find or synthesize mg to kg amounts of chemical building blocks, scaffolds and reactive intermediates.
  • Discovery Computational Chemistry Model the interaction of a drug candidate with protein targets such as kinases, GPCRs, receptors, ion channels or enzymes.
  • Fragment Libraries Find fragment libraries for screening against a protein or cellular target.
  • Hit to Lead (H2L) Evaluate, perform limited optimization and identify small molecule hits from high throughput screens.
  • HTS Libraries Find targeted and broad collections of chemical compounds for high throughput screening and ADMET applications.
  • In Silico Lead Optimization Use in silico design to enhance the ADME-PK properties of candidate drugs to maximize efficacy and safety.
  • In Silico Metabolite Predictions Conduct in silico assessment of metabolite pharmacokinetic properties and potential exposure effects.
  • Lead Optimization Perform chemical structural changes to improve preclinical drug candidate.
  • Library Design & Evaluation Use structural knowledge to design target-focused compound libraries for screening.
  • Pharmaceutical Research Chemicals Acquire chemicals that are prospective new drug entities.
  • Pharmacophore Modeling Use computer models to identify hits based on structural similarity to known active compounds.
  • QSAR Analysis Develop quantitative structure–activity relationship models for drug design.
  • Target-Focused Compound Libraries Find activity-based libraries directed towards a protein or cell signaling target.
  • USP Testing Analytical Reagents Acquire chemical reagents, solution concentrates and volumetric solutions used to evaluate items in USP testing.
  • USP-NF Grade Chemicals Acquire chemicals that comply with United States Pharmacopeia and National Formulary standards.
  • Virtual Screening Use software algorithms to virtually screen millions of potential compounds and peptides for binding.
Show all 67 services 53 more

DNA & RNA

  • Sequence Based Methylation Analysis Detect DNA methylation sites within cytosine-phosphate-guanine (CpG) dinucleotides at single base-pair resolution.

General Marketing

  • Database Management Software Facilitate the collection, tracking and processing of biological facts, statistics and observations.

In Vitro ADME

  • CYP Induction Detect increases in the expression of various isoforms of cytochrome P450 (CYP450).
  • CYP Inhibition Assay Assess the inactivation and inhibition of cytochrome P450 (CYP450) in microsomes isolated from primary human hepatocytes or liver.
  • CYP Isozyme Mapping Determine the isozymes of cytochrome P450 (CYP450) involved in the metabolism of a drug candidate.
  • Cytochrome P450s Assess the inhibition or induction of the various isozymes of cytochrome P450s by drug candidates.
  • GI Fluid Stability Determine dosing and turnover of drug candidates in gastrointestinal fluids.
  • Metabolic Stability Measure metabolic vulnerability to drug metabolizing enzymes using cell-free, cell-based and in vivo assays.
Show all 9 in In Vitro ADME 3 more
  • Metabolic Stability in Hepatocytes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver cells.
  • Metabolic Stability in Microsomes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver microsomes.
  • Plasma Stability Assay Determine degradation rate of drug candidates in plasma.

In Vitro Pharmacology

  • Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
  • High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.

Protein Sciences

  • Peptide Derivatives Acquire chemicals that are peptide derivatives.

Scientific Data Services

  • Bioinformatics Bioinformatics is a powerful method of storing, retrieving and analyzing biological data.
  • Cancer Systems Biology Convert complex molecular data obtained from high-throughput technologies to deducible information.
  • Data and Text Mining Derive structured data from free text in order to become accessible for data-mining algorithms.
  • Database Integration Convert bioinformatics results from multiple data sources (DSs) into a single operational format.
  • Discovery Computational Systems Biology Model the interaction of biological system with drug candidates.
  • Epigenomics Data Analysis Quantify and analyze DNA methylation and/or DNA binding protein data sets.
Show all 14 in Scientific Data Services 8 more
  • In Silico Genomics/Transcriptomics Data Analysis Interpret DNA sequencing and microarray data.
  • In Silico Metagenomics/Metatranscriptomics Data Analysis Use software to analyze genomic information from multiple environmental sources.
  • Molecular Dynamics Software Run simulations that determine time-dependent behaviors of molecular systems.
  • Molecular Phylogenetics Analyze hereditary molecular differences in genomic sequences to compare genomes.
  • Software Tools Software tool for statistical analysis, data mining, genome annotation or NGS data analysis.
  • Systems Biomedicine Analyze complex interactions in biological systems with interdisciplinary scientific teams.
  • Systems Network Analysis Analyze and visualize molecular pathways including gene regulatory, protein-protein and drug-target networks.
  • Systems Pharmacology Understand how drugs interact with different molecular and cellular systems within biological models.

Other services

  • New Request  

Service areas:

Chemistry

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • United Kingdom London 2 sites

Source: Scientist.com supplier network (site locations)

About this supplier

In the supplier's own words, as listed in the Scientist.com network.

DigitalBioPharm ltd - a Research and Development company, was founded to provide IT-solutions usage in drug discovery and biotechnology. PRECLIINICAL DRUG DISCOVERY Please find full drug discovery services description in this PDF Early-stage drug discovery services (read more) Structure-based drug design Ligand-based drug design Molecular modeling Adme/tox optimization Medicinal and organic chemistry Hi2lead optimization Drug discovery management Project planning and disease selection (including orphan) Biotargets prioritization, selection and validation Preclinical trials organization 3D...

Show the full description

DigitalBioPharm ltd - a Research and Development company, was founded to provide IT-solutions usage in drug discovery and biotechnology.

PRECLIINICAL DRUG DISCOVERY

Please find full drug discovery services description in this PDF

Early-stage drug discovery services (read more)

Structure-based drug design
Ligand-based drug design
Molecular modeling
Adme/tox optimization
Medicinal and organic chemistry
Hi2lead optimization

Drug discovery management

Project planning and disease selection (including orphan)
Biotargets prioritization, selection and validation
Preclinical trials organization

3D ANIMATION

Biomedical animation
3D movies
Scientific scenario writing and editing

INVESTMENTS

Investments consulting
Technology hunting
Due dilligence

OTHER SERVICES

Publications review.

This is basically done for each part of the drug discovery services, but can be ordered as a separate service.
Analysis of patent environment
Patent search and patent purity evaluation for drug candidates.
Patents preparation and exemplification drug development projects
Patents breaking, patents exemplification
Investments and grants funding proposal preparations
Grant funding review and updates worldwide personalized for your research profile.
Grant announcements and deadlines alarms. The same service we offer for the conferences.
Distributed computing solutions for computational science. Organization of local network resources into virtual supercomputer-like computational facilities (software like Condor, Boinc)
Development of software for high throughput processors of GPU and processors of cell type (sony playstation 3)

Website
www.digitalbiopharm.com

Source: Scientist.com supplier network, written by the supplier

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Sources: Scientist.com supplier network.

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