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Research supplier
Source Bioscience
Source Bioscience is listed as a small business research supplier in the Scientist.com network, with 4 sites in 1 country and 2 service areas.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Biomarkers
- Biomarker Discovery Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.
- Diagnostic Biomarkers Discovery Identify candidate biomarkers indicative of the presence of a disorder.
- Digital Pathology Acquire, manage and interpret pathology information generated from a digital image of a slide preparation of cells or tissue.
- Epigenetics Epigenetics sits at the cutting edge of drug discovery. The ability to modify genomes without changing any sequences with methylation.
- Fluorescent In Situ Hybridization Use FISH to identify abnormal chromosome structures and to quantify specific DNA sequences.
- Hematoxylin & Eosin (H&E) Staining Visualize microscopic structures in cells or tissues.
Show all 12 in Biomarkers
- Histopathology Evaluate slide preparation of cells or tissues for abnormal features.
- Immunohistochemistry Examine the toxic effects of pre-clinical compounds in small animal and patient histological samples.
- Microbiome Services Examine the community of commensal, symbiotic, and pathogenic microorganisms that make up the microbiome.
- Multi-Omics Study Use an integrated multi-omics study to understand a disease mechanism.
- Paraffin-based Histology Perform sectioning and histological analysis of wax-embedded samples.
- Solid Tumor CDx Design and validate companion diagnostics for solid tumors that help select the most appropriate patients, identify patients at increased risk, or monitor treatment effectiveness.
Cell Culture and Characterization
- Histology Examine by microscopy the anatomy of cells and tissues of clinical patients and animal models.
- Microsatellite Instability Analysis Compare allelic profiles and detect genomic instability.
- Single Cell DNA Sequencing Examine genetic variations in a single cell.
- Single Cell Services Request services to perform genomics, transcriptomics, proteomics, metabolomics and cell–cell interactions at the single cell level
- STR Profiling - Microsatellite Short Tandem Repeat Confirm cell line identity and detect cross-contamination.
Chemical and Compound Analysis
- Chemical Stability Measure the stability of small molecules in solution.
- Photostability Measure drug degradation rates after exposure to various light sources.
Show all 66 services
Chemical and Compound Testing
- Clinical Pathology Diagnose disease based on the laboratory analysis of bodily fluids, such as blood, urine and tissues.
Chemistry, Manufacturing and Controls (CMC)
- API and drug product storage and release API and drug product storage and release
- API Stress Testing Studies Develop analytical methods to predict stability problems and identify degradation products/pathways under forced degradation conditions.
- Drug Product Stability Use accelerated stress conditions to determine degradation pathways and identify manufacturing issues.
- Forced Degradation Run light, heat, humidity, acid hydrolysis and oxidation tests to evaluate substance degradation.
- ICH-compliant stability testing Perform ICH-compliant stability testing
Companion Diagnostics
- Cervical Cancer CDx Design and validate companion diagnostics for cervical cancer that help select the most appropriate patients, identify patients at increased risk, or monitor treatment effectiveness.
- Pancreatic Cancer CDx Design and validate companion diagnostics for pancreatic cancer that help select the most appropriate patients, identify patients at increased risk, or monitor treatment effectiveness.
Data Science/Bioinformatics
- In Silico Cancer Genomics/Cancer Transcriptomics Analysis Interpret DNA sequencing and microarray data for cancer studies.
DNA & RNA
- cDNA cloning & subcloning Move cDNA fragments between different cloning vectors.
- cDNA library construction Generate a library of recombinant cDNA clones.
- De Novo Genome Sequencing Determine the DNA sequence of uncharacterized genomes.
- De Novo Transcriptome Sequencing Identify new genes without the need for a reference genome sequence.
- DNA Sequencing Determine the nucleotide sequence of DNA samples.
- Exome Sequencing Determine protein-coding nucleotide sequences in a DNA sample.
Show all 27 in DNA & RNA
- Genomic DNA Purification Isolate genomic DNA from cells or tissue samples.
- Long Read Sequencing Long read sequencing is used in genomics to sequence long fragments of DNA, enabling the ability to span complex regions of the genome.
- Metagenomic Sequencing Sequence genetic material recovered directly from environmental samples
- Methylation Analysis Determine genomic methylation patterns and analyze methylation in tumors and treated samples.
- miRNA sequencing Identify miRNAs by Next Generation Sequencing and bioinformatic analysis.
- qPCR Analysis Measure the accumulation of PCR products in real time.
- Quantitative RT PCR Use quantitative reverse transcription polymerase chain reaction to measure absolute and relative mRNA abundance.
- RNA Extraction Isolate total RNA or mRNA from cells or tissues
- RNA Profiling Quantify the expression levels of mRNA transcripts, enabling the determination of gene expression patterns.
- RNA Sequencing Use Next Generation Sequencing techniques to Identify RNA transcripts, examine differential expression patterns and analyze splice variants.
- RNA Sequencing/Resequencing Identify RNA transcripts, examine differential expression patterns and analyze splice variants.
- RNA Services Whether you’re isolating total RNA for whole genome expression analysis by microarray or setting up high content screening by s...
- Sanger Sequencing Sequence single strand DNA fragments using DNA Polymerase.
- Sequence Based Methylation Analysis Detect DNA methylation sites within cytosine-phosphate-guanine (CpG) dinucleotides at single base-pair resolution.
- SNP Characterization Identify single nucleotide polymorphisms to make genetic associations, analyze disease SNPs and determine LOH.
- Target Gene Expression Measure expression of a target gene at the protein, RNA and DNA level.
- Targeted Sequencing/Resequencing Detect variations in a genome subset.
- Tissue Microarray Screen large numbers of tissues for the presence or absence of specific molecular markers.
- Total RNA Sequencing Identify novel RNA transcripts and detect gene expression changes.
- Whole Genome Amplification (WGA) Amplify an entire genome from a single cell.
- Whole Genome Sequencing Determine the entire genetic make-up of an organism.
In Vitro Assays
- Virus Detection Assays Use ultra-sensitve methods to reliably detect low level viruses.
Other Specialty Toxicology
- Microbial Testing Test samples for microorganisms, identify species, do bioburden analysis and measure endotoxin levels (LAL).
Protein Sciences
- Proteomics Do large-scale experimental analysis of proteins focused on understanding structure and function.
Safety Pharmacology
- Tissue Cross Reactivity Assess the toxic effects of humanized monoclonal antibodies in 33 normal types recommended by the FDA.
Scientific Data Services
- Bioinformatics Bioinformatics is a powerful method of storing, retrieving and analyzing biological data.
- Metagenomics Data Analysis Deconvolute the genetic content of genomes contained in environmental samples by utilizing whole genome sequencing techniques to provide insight into microbial communities and host phenotypes.
Testing Services
- Accelerated Stability Determine shelf life of drug formulations by comparing API breakdown at elevated temperature.
- Freeze-Thaw Testing Use freeze-thaw cycling to measure the long-term durability of cosumer products.
- Package Compatibility Tests Ensure that the consumer product is not adversely affected by the package components and vice versa.
- Real-time Stability Test Assure stability and physical integrity of consumer products in real-time conditions.
Other services
- New Request
Service areas:
Where it operates
Sites by country, with the cities in each.
-
United Kingdom 4 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Source BioScience is an international business providing high quality services and products to the pharma biotech, life science research and healthcare diagnostic communities. The Company provides capillary electrophoresis DNA sequencing, next generation sequencing (‘NGS’), genomic services (including genotyping, gene expression and microarray services) and bioinformatic analyses. In addition the Company also offers a comprehensive portfolio of life science products. The Company operates an international network of state of the art facilities, with UK laboratories in Oxford, Cambridge...
Show the full description
Source BioScience is an international business providing high quality services and products to the pharma biotech, life science research and healthcare diagnostic communities. The Company provides capillary electrophoresis DNA sequencing, next generation sequencing (‘NGS’), genomic services (including genotyping, gene expression and microarray services) and bioinformatic analyses. In addition the Company also offers a comprehensive portfolio of life science products. The Company operates an international network of state of the art facilities, with UK laboratories in Oxford, Cambridge, Nottingham, Rochdale and Glasgow; European facilities in Berlin, Germany and Waterford City, Ireland and US facilities in Los Angeles and Atlanta.
Source BioScience is an Illumina CSPro™ certified service provider. The CSPro™ program is a collaborative service partnership with Illumina that is dedicated to ensuring delivery of the highest-quality data available for genetic analysis applications. The Illumina CSPro™ certification provides us with a competitive advantage as it gives our customers reassurance and confidence in receiving industry-leading data quality and service.
Source BioScience also has CPA accreditation for our histology and molecular diagnostics service and is Good Laboratory Practice (GLP) and Good Clinical Practice (GCP) accredited by the Medicines and Healthcare Regulatory Agency (MHRA). In addition to the above, we are licensed by the Human Tissue Authority (HTA) and are compliant with the Care Quality Commission (CQC).
Source BioScience is a UK business headquartered in Nottingham and listed on the London Stock Exchange (LSE: SBS). The Company is therefore subject to rigorous Corporate Governance and regulatory requirements which provides our customers and partners with reassurance as to the financial integrity of the Company and its ability to commit to, and deliver on, long term contracts.
- Website
- www.sourcebioscience.com
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