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Psomagen Inc. (formerly Macrogen Corp.)

Psomagen Inc. (formerly Macrogen Corp.) is listed as a mid sized business research supplier in the Scientist.com network, with 7 sites in 3 countries and 1 service area.

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Sites 7
Countries 3

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Mid sized business

Antibodies

  • Antibody Protein De Novo Sequencing Sequence antibody proteins using multiple enzyme digestion and high-resolution LC-MS/MS.
  • Antibody Sequencing Sequence cDNA encoding variable heavy (VH) and variable light (VL) domains of a hybridoma cell line.

Bioimaging

  • Microscopy Use microscopy to analyze surfaces of biological materials and to develop 3D images of biological structures.

Biomarkers

  • Anatomic Pathology Do macroscopic, microscopic, biochemical, immunologic and molecular examination of organs and tissues.
  • Biomarker Clinical Validation Evaluate the predictive ability of a candidate biomarker for a disorder.
  • Biomarker Discovery Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.
  • Diagnostic Biomarkers Discovery Identify candidate biomarkers indicative of the presence of a disorder.
  • Digital Pathology Acquire, manage and interpret pathology information generated from a digital image of a slide preparation of cells or tissue.
  • Epigenetics Epigenetics sits at the cutting edge of drug discovery. The ability to modify genomes without changing any sequences with methylation.
Show all 20 in Biomarkers 14 more
  • Fluorescent In Situ Hybridization Use FISH to identify abnormal chromosome structures and to quantify specific DNA sequences.
  • Hematoxylin & Eosin (H&E) Staining Visualize microscopic structures in cells or tissues.
  • Histopathology Evaluate slide preparation of cells or tissues for abnormal features.
  • Immunohistochemistry Examine the toxic effects of pre-clinical compounds in small animal and patient histological samples.
  • Microbiome Services Examine the community of commensal, symbiotic, and pathogenic microorganisms that make up the microbiome.
  • Multi-Omics Study Use an integrated multi-omics study to understand a disease mechanism.
  • Paraffin-based Histology Perform sectioning and histological analysis of wax-embedded samples.
  • Predictive Biomarkers Discovery Identify candidate biomarkers suggestive of a response to a treatment.
  • Prognostic Biomarkers Discovery Identify candidate biomarkers representative of disease progression without treatment.
  • Single Cell Isolation Isolate single cells for subsequent single-cell analysis.
  • Single Cell quantitative Real Time-PCR Assess gene expression levels and patterns in a single cell.
  • Single Cell Transcriptome Sequencing Detect distinct, rare or abnomal cell types in a heterogenous population.
  • Special Stainings Use a variety of techniques for the selective visualization of specific tissue or cell types.
  • Whole Transcriptome Amplification Amplify total RNA from a single cell.

Cell Culture and Characterization

  • Cell and Tissue Histology Prepare and stain frozen, fixed and embedded (FFPE) tissue samples.
  • Cryo-based Histology Perform sectioning and histological analysis of frozen non-fixed samples.
  • H & E Services For requesting services related to H&E Services
  • Histology Examine by microscopy the anatomy of cells and tissues of clinical patients and animal models.
  • Microsatellite Instability Analysis Compare allelic profiles and detect genomic instability.
  • Signaling Pathways Find proteins, assays and custom reagents for the analysis of cell signaling pathways.
Show all 8 in Cell Culture and Characterization 2 more
  • Single Cell DNA Sequencing Examine genetic variations in a single cell.
  • Single Cell Services Request services to perform genomics, transcriptomics, proteomics, metabolomics and cell–cell interactions at the single cell level
Show all 114 services 99 more

Clinical Trials

  • Clinical Research Services Determine the safety and effectiveness of medications and medical devices.

Data Science/Bioinformatics

  • Biostatistical Design Use statistics to ensure appropriate pre-clinical and clinical study design.
  • Clinical Biomarker Analysis An approach to finding markers that change in response to a drug or that identify a group that responds favorably to a specific therapy. These can be omics, molecular, histologic, radiologic, etc.
  • Clinical In Silico Genomics/Transcriptomics Data Analysis A process that helps make sense of your omics data
  • Discovery Statistical and Mathematical Modeling Use mathematical variables and equations to establish relationships between data.
  • Translational Biomarker Discovery An approach to finding markers that change in response to a drug or that identify a group that responds favorably to a specific therapy. These can be omics, molecular, histologic, radiologic, etc.

DNA & RNA

  • Amplicon - HLA Typing Use an amplicon sequencing method to identify allelic variation within the HLA genes.
  • Amplicon 16s rRNA Sequencing Identify and compare bacteria present within a given sample.
  • Bisulfite Seq DNA Methylation Analysis Determine DNA methylation status at single-base resolution
  • Bisulfite Sequencing (RRBS) Analyze genome-wide methylation profiles on a single nucleotide level.
  • Capillary Electrophoresis Separate ng quantities of DNA to single base resolution.
  • cDNA library construction Generate a library of recombinant cDNA clones.
Show all 55 in DNA & RNA 49 more
  • Cell Free DNA Assay Detect known mutations and discover new ones in cell-free plasma DNA.
  • ChIP-Sequencing Use chromosome immunoprecipitation to identify DNA-protein binding sites in a genome.
  • ChIP-sequencing Profiling Identify where a protein is binding to DNA on a genome-wide scale.
  • De Novo Genome Sequencing Determine the DNA sequence of uncharacterized genomes.
  • De Novo Transcriptome Sequencing Identify new genes without the need for a reference genome sequence.
  • DNA Extraction Extract DNA from an original source.
  • DNA Hydroxy Methylation Seq Use epigenetic services to analyze genome-wide DNA hydroxymethylation.
  • DNA Library Screening Screen genomic or cDNA libraries for positive clones.
  • DNA Sequencing Determine the nucleotide sequence of DNA samples.
  • DNA/RNA Extraction & Purification DNA/RNA Extraction & Purification.
  • Exome Sequencing Determine protein-coding nucleotide sequences in a DNA sample.
  • Expression Profiling Measure the the expression of thousands of genes at once to create a global picture of cellular function.
  • Genomic DNA Purification Isolate genomic DNA from cells or tissue samples.
  • Genotyping Examine a DNA sequence to identify specific genetic varients .
  • In Situ Hybridization Localize specific nucleic acid targets using labeled complementary probes.
  • Integrated Genomics Package Process an entire Genomics Pipeline Project including: Sample Preparation, Target Enrichment, NGS Instrumentation, and Data Analysis from our Bundle of Suppliers
  • Metagenomic Sequencing Sequence genetic material recovered directly from environmental samples
  • Methylation Analysis Determine genomic methylation patterns and analyze methylation in tumors and treated samples.
  • Methylation Specific PCR Determine the methylation status of a CpG site without the need for base-specific endonucleases.
  • miRNA sequencing Identify miRNAs by Next Generation Sequencing and bioinformatic analysis.
  • mRNA synthesis Transcribe mRNAs in vitro and add modifications such as polyadenylation and guanine capping.
  • mtDNA Sequencing Use next-generation sequencing (NGS) technology to detect and analyze mitochondrial mutations.
  • Multiplex Cellular miRNA Assay Use Firefly™ technology for multiplex cellular microRNA profiling.
  • NGS: Next Generation Sequencing Sequence millions of template DNA molecules in parallel.
  • Non-Bisulfite DNA Methylation Analysis Analyze DNA methylation by methods such as differential enzymatic cleavage or affinity capture
  • Plasmid DNA Preparation and Extraction Prepare plasmid DNA starting from E. coli cell pellets, transformed colonies or DNA samples.
  • qPCR Analysis Measure the accumulation of PCR products in real time.
  • Quantitative RT PCR Use quantitative reverse transcription polymerase chain reaction to measure absolute and relative mRNA abundance.
  • RAD Sequencing Examine a small percentage of the target genome.
  • RNA Amplification Produce RNA from pre-clinical and clinical samples for use in gene expression studies.
  • RNA Extraction Isolate total RNA or mRNA from cells or tissues
  • RNA oligo synthesis Design and synthesize miRNAs, siRNAs and other non coding RNAs
  • RNA Profiling Quantify the expression levels of mRNA transcripts, enabling the determination of gene expression patterns.
  • RNA Sequencing Use Next Generation Sequencing techniques to Identify RNA transcripts, examine differential expression patterns and analyze splice variants.
  • RNA Sequencing/Resequencing Identify RNA transcripts, examine differential expression patterns and analyze splice variants.
  • Sanger Sequencing Sequence single strand DNA fragments using DNA Polymerase.
  • Sequence Based Methylation Analysis Detect DNA methylation sites within cytosine-phosphate-guanine (CpG) dinucleotides at single base-pair resolution.
  • Single Cell RNA Sequencing Quantify mRNA variants in a single cell.
  • Single Molecule Real Time Sequencing Monitor the incorporation of fluorescently conjugated nucleotides within zero-mode waveguide (ZMW) chambers.
  • SNP Characterization Identify single nucleotide polymorphisms to make genetic associations, analyze disease SNPs and determine LOH.
  • Target Gene Expression Measure expression of a target gene at the protein, RNA and DNA level.
  • Targeted Bisulphite Sequencing Reveal changes in DNA methylation associated with nuclear reprogramming.
  • Targeted Sequencing/Resequencing Detect variations in a genome subset.
  • TCR Repertoire Sequencing Analyze the T cell receptor repertoire by means of next-generation sequencing.
  • Total RNA Sequencing Identify novel RNA transcripts and detect gene expression changes.
  • Whole Genome Amplification (WGA) Amplify an entire genome from a single cell.
  • Whole Genome Bisulphite Seq Profile genome-wide DNA methylation.
  • Whole Genome Profiling Develop sequence-based physical maps for the assembly of genomes.
  • Whole Genome Sequencing Determine the entire genetic make-up of an organism.

Drug Development

  • Bioinformatics Consulting Consulting Services for the science of collecting and analyzing complex biological data

In Vitro Pharmacology

  • Polymerase Assays Measure polymerase activity in biochemical and cell-based assays.

Protein Sciences

  • Cytokines Find recombinant cytokines or cytokine assays.
  • Protein Expression Produce recombinant proteins in prokaryotic or eukaryotic systems.
  • Protein Identification Uncover or confirm the identity of a protein.
  • Protein Sequencing Determine the amino acid sequence of protein or peptide.
  • Proteomics Do large-scale experimental analysis of proteins focused on understanding structure and function.

Scientific Data Services

  • Bioinformatics Bioinformatics is a powerful method of storing, retrieving and analyzing biological data.
  • Cancer Systems Biology Convert complex molecular data obtained from high-throughput technologies to deducible information.
  • Epigenomics Data Analysis Quantify and analyze DNA methylation and/or DNA binding protein data sets.
  • Metagenomics Data Analysis Deconvolute the genetic content of genomes contained in environmental samples by utilizing whole genome sequencing techniques to provide insight into microbial communities and host phenotypes.
  • Microbiome Data Analysis Determine the population composition of a microbial community and analyze its contribution to human or animal health.
  • Molecular Phylogenetics Analyze hereditary molecular differences in genomic sequences to compare genomes.
Show all 13 in Scientific Data Services 7 more
  • Mutation Data Profiling Guide treatment decisions in cancer based on the identification of genomic mutations .
  • Omics Informatics Consulting Services for the analysis of large-scale molecular data sets.
  • Pharmaco-genomics Genetic polymorphism contribution to inter-individual variability in drugs' responses and/or adverse events.
  • Scientific Data Visualization Exploration and reporting of data by means of graphs and plots.
  • Scientific Pipeline Implementation Design, develop and deploy data analyses workflows.
  • Small RNA Gene Expression Quantify and analyze miRNA, piRNA, siRNA as well as other small nuclear RNAs from small-RNA-seq raw input data sets.
  • Systems Pharmacology Understand how drugs interact with different molecular and cellular systems within biological models.

Other services

  • New Request  
  • Transcriptome In Vivo Analysis (TIVA) Use TIVA for photo-activated capture of mRNA from a single cell or sub-cellular region.

Service areas:

Biology

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • United States Brooklyn, Cambridge, Rockville 5 sites
  • Japan 泉南郡 1 site
  • Netherlands Amsterdam 1 site

Source: Scientist.com supplier network (site locations)

About this supplier

In the supplier's own words, as listed in the Scientist.com network.

In 2005, under the tutelage and guidance of Macrogen, Inc. (Korea), Macrogen Corp. opened its laboratory in Rockville, Maryland to serve your DNA sequencing needs. Since our humble beginnings, Macrogen Corp. has grown to surpass our competition as one of the foremost providers of traditional Sanger Sequencing through top-quality services at industry-competitive prices. By adapting to cutting-edge technologies, evolving sequencing platforms, and utilizing the invaluable knowledge and expertise of our staff, Macrogen Corp. continues to strive to provide the absolute best quality results...

Show the full description

In 2005, under the tutelage and guidance of Macrogen, Inc. (Korea), Macrogen Corp. opened its laboratory in Rockville, Maryland to serve your DNA sequencing needs.

Since our humble beginnings, Macrogen Corp. has grown to surpass our competition as one of the foremost providers of traditional Sanger Sequencing through top-quality services at industry-competitive prices.

By adapting to cutting-edge technologies, evolving sequencing platforms, and utilizing the invaluable knowledge and expertise of our staff, Macrogen Corp. continues to strive to provide the absolute best quality results at the fastest possible turnaround time to our clients.

Our reputation is spanning the globe and is never more evident by the exponential growth of our client base both nationwide and worldwide. Some of our more notable clients include researchers from the National Institute of Health (NIH), the National Cancer Institute (NCI), and the Food and Drug Administration (FDA) who have grown to trust and rely on Macrogen Corp. for their everyday sequencing needs.

With the success of our flagship company in Maryland, we were able to open a sequencing facility in New York. This branch maintains the highest quality and caliber service to clients to the Tri-State Area, and is a blueprint for the expansion of Macrogen Corp. throughout North America and to your front steps.

Macrogen Corp. attributes the success and growth of this company to the dedication and commitment of not only our staff, but of our clients. It is you, our client, who fuels our passion to be the leader in our industry and wills us to strive to exceed your sequencing needs and it is with you who Macrogen Corp. will continue trailblazing in genomic-based research.

Together, we are "Advancing through Genomics".

Website
www.psomagen.com

Source: Scientist.com supplier network, written by the supplier

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