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Microbac Laboratories

Microbac Laboratories is listed as a mid sized business research supplier in the Scientist.com network, with 28 sites in 1 country and 2 service areas.

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Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 28

Countries 1

Type of company: Mid sized business

Agricultural Sciences Compliance and Quality Control Measures

GMO Seed Testing Evaluate whether or not a seed has been genetically altered from its native state.
Non-GMO Certification Ensure compliance with non-GMO standards and obtain formal recognition.

Antibodies

Hybridoma Sequencing/Antibody Sequencing Determine the sequences of monoclonal antibodies.

Biomarkers

Antimicrobial Effectiveness Testing Measure the efficacy of anti-microbial preservatives added to a product.
Single Cell quantitative Real Time-PCR Assess gene expression levels and patterns in a single cell.

Cell Culture and Characterization

Single Cell DNA Sequencing Examine genetic variations in a single cell.
Viral Mediated Gene Delivery Use viral carriers to introduce new genetic material into a cell.

Chemical and Compound Analysis

Amino Acid Analysis (AAA) Determine protein quantities, relative compositions and amino acid content profiles.
API Physical Characteristics Characterize physical and chemical properties of new drug molecules to develop safe, effective, and stable dosage forms.
Dissolution Profiling Measure release of API from formulation (tablet or capsules) under GMP guidelines.
Elemental Impurity Analysis Identify and evaluate the presence of heavy metals in pharmaceuticals.
Endotoxin Testing Use standard assays like LAL (Limulus Amebocyte Lysate), rFC (Recombinant Factor C), or MAT (Monocyte Activation Test) to detect and quantify the level of endotoxins in a sample
Headspace Gas Chromatography Analyze volatile organic compounds (VOCs) partitioned above the liquid/solid phase of a sample.

Show all 13 in Chemical and Compound Analysis 7 more

Heavy Metals Analysis Ensure trace levels of heavy metals are below the maximum allowable limits for consumer safety.
Inductively Coupled Plasma (ICP) Analysis Characterize ultra-small levels of multiple solid analytes simultaneously.
Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) Analysis Detect metals and several non-metals at concentrations as low as one part in 1015 (part per quadrillion, ppq) on non-interfered low-background isotopes.
Liquid Chromatography Separate substances using a mobile and stationary phase.
Process Residual Impurities Detection Measure trace levels of impurities.
Secondary Ion Mass Spectrometry Detect trace level impurities and obtain elemental or molecular chemical data for solid sample surfaces.
UV-Spectroscopy Conduct sample analysis based on light absorption and transmission.

Show all 122 services 109 more

Chemical and Compound Testing

Bacterial Water Analysis Analyzing water samples to identify the bacteria present.
Limulus Amebocyte Lysate (LAL) Test Detect bacterial endotoxins in raw materials used for the production of cosmetics products.
Nutritional Testing Analyze food safety, vendor specifications, foreign substance identification processes and nutritional labeling.
Product Testing Ensure product quality standards are met.
Supplement/Vitamin Testing Assess the composition, strength, identity, quality and purity of nutraceuticals.
USP <2021> Microbial Enumeration Tests Estimate the total aerobic microbial count, total combined yeast and mold counts, and the presence of bile-tolerant gram-negative bacteria present in nutritional supplements.

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USP <2022> Microbiological Procedures for Absence of Specified Microorganisms Determine the absence of objectionable organisms in nutritional supplements.
USP <85> Bacterial Endotoxin Test Test to detect or quantify bacterial endotoxins that may be present in or on a sample.

Chemistry, Manufacturing and Controls (CMC)

API/ Excipients Compatibility Studies Delineate real and possible interactions between potential formulation excipients and the API as an important risk reduction exercise early in formulation development.
Chemistry Manufacturing Controls Access contract manufacturing and regulatory guidance in setting specifications and drug dosage formulations.
Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services

Clinical Consulting

Clinical Protocol Design & Development Creation of clinical protocol document which details how a clinical trial is designed, relating to to the methodology, hypothesis, and operation of clinical trial to ensure the safety of the patients is...

Clinical Trials

Bioequivalence Studies Assess the expected biological equivalence of two proprietary preparations of a drug.
Consumer Healthcare Product Trials Conduct clinical research to ensure the safety and efficacy of consumer healthcare products used for oral care, skin care, nutrition, and hair care.

Developmental and Reproductive Toxicology (DART)

Reproductive Toxicology Study adverse sexual function and fertility and examine teratogenicity of compounds.

Discovery Chemistry

LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.

DNA & RNA

Metagenomic Sequencing Sequence genetic material recovered directly from environmental samples
qPCR Analysis Measure the accumulation of PCR products in real time.
Quantitative RT PCR Use quantitative reverse transcription polymerase chain reaction to measure absolute and relative mRNA abundance.
RNA Profiling Quantify the expression levels of mRNA transcripts, enabling the determination of gene expression patterns.
RNA Sequencing Use Next Generation Sequencing techniques to Identify RNA transcripts, examine differential expression patterns and analyze splice variants.
Target Gene Expression Measure expression of a target gene at the protein, RNA and DNA level.

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Whole Genome Sequencing Determine the entire genetic make-up of an organism.

Drug Development

Safety Pharmacology Consulting Consulting services that help with the detection of potential undesirable pharmacodynamic effects of chemical entities on physiological functions.

Effectiveness

Antimicrobial Pharmacodynamics Ascertain the effectiveness of an antimicrobial compound and test levels of antibiotic resistance against specific bacterial pathogens.
Bioequivalence Studies for Veterinary Drugs Assess the expected biological equivalence of two proprietary preparations of a veterinary drug.
In Vitro Dose Determination Tests Determine the most appropriate effective drug dosage regimen(s) in vitro.
Laboratory Dose Confirmation Studies Conduct in vivo studies to confirm the effectiveness of a selected drug dose in the lab.
Minimum Bactericidal Concentration (MBC) Test Assess the bactericidal activity of a test compound.

Food Safety & Regulations

Anaerobic Plate Count Determine the total anaerobic bacteria present in a food or contact-surface sample.
Clostridium perfringens Tests Ensure food and water safety by detecting the presence of C. perfringens, its spores or the toxins in samples.
E.coli 0157 Tests Isolate and identify the presence of a distinct variant of the E.coli species or its potent toxin in food, water or contact-surface samples.
E.coli spp. Testing Use molecular, immunological or cultured methods to detect the presence of E.Coli species in samplings from food, water, contact surfaces or another source.
FDA Food Nutrition Facts Label Testing Analyze a food or dietary product for food labelling purposes as required by the FDA or USDA.
Free Coagulase Test Use a tube test to determine whether or not the S.aureus species is present in Staphylococcus isolates from a sample.

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Listeria monocytogenes Tests Assess product samples or the direct contact surfaces for a specific and prevalent Listeria species capable of growth at low temperatures.
Listeria spp. Testing Use molecular, immunological or cultured methods to identify potential growth sites for all species of the Listeria genus.
Norovirus spp. Testing Use molecular, immunological or microscopic methods to detect and quantify Norovirus species in food, water or contact-surface samples.
Pseudomonas aeruginosa Testing Use molecular, immunological or cultured methods to confirm the presence or absence of P.aeruginosa in samples from food, water or processing surfaces.
Pseudomonas spp. Testing Detect the presence and abundance of various cold-tolerant Pseudomonas species that cause or contribute to spoilage in meat, poultry, seafood, dairy or beverages.
Salmonella spp. Testing Use molecular, immunological or cultured methods to identify the presence of Salmonella species in food or contact-surface samples.
Total Coliform Testing Measure the bacterial content of a sample to assess food safety, efficacy of sanitation methods or handling practices.
Water Activity Determine water activity in consumer healthcare products involving a USP or FCC monograph.

General in vivo Toxicology

General Toxicology Use in vivo models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.
Mammalian Toxicology Use toxicity testing models to carry out required FDA or REACH safety testing.
Oral Toxicology Use toxicity studies in animals to evaluate the oral toxicity of a drug candidate.

In Vitro Assays

In Vitro Efficacy Test Use in vitro models to test the efficacy of your products.
In Vitro SPF (Sun Protection Factor) Testing Use in vitro test methods to measure the UVA protection performance of sun protection products.
Porcine Cornea Reversibility Assay (PorCORA) Measure corneal damage and recovery in excised porcine corneas.
Viral Clearance Assays Measure the capacity to remove or inactivate infectious agents during the manufacturing process.

In Vitro Pharmacology

High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
In Vitro Hepatotoxicity Assays Use in vitro assays to measure hepatoxicity-related activities.
Target Identification Identify the target(s) of a biologically active substance.

In Vitro Toxicology

Cytotoxicity Test for effects on cell viability and proliferation
Cytotoxicity Testing Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.
Zebrafish Embryo Toxicity Use a single animal species to create one models of toxicity.

Other Specialty Toxicology

Microbial Testing Test samples for microorganisms, identify species, do bioburden analysis and measure endotoxin levels (LAL).
Residual DNA Analysis Measure contaminants found in therapeutics like biologicals and biosimilars that are produced in cells.
United States Pharmacopeia (USP) Testing Use USP standards to ensure quality of pharmaceuticals, supplements and food ingredients.
Viral Testing Characterize viral products for functional activity and possible contamination.

Protein Sciences

Western Blots Detect specific proteins in a sample of tissue homogenate or extract.

REACH Services

OECD 429: Skin Sensitisation (Local Lymph Node Assay) Assess the skin sensitization potential of chemicals.
OECD 432: In Vitro 3T3 NRU Phototoxicity Test Test the cytotoxic effects of chemical substances and environmental samples on cell membranes.
OECD 471: Bacterial Reverse Mutation Test (Ames) Measure the mutagenic potential of test compounds.
OECD 473: In Vitro Mammalian Chromosomal Aberration Test Assess the ability of the test substance to cause structural chromosomal aberrations in cultured mammalian cells.
OECD 475: Mammalian Bone Marrow Chromosomal Aberration Test The mammalian in vivo chromosome aberration test is used for the detection of structural chromosome aberrations induced by test compounds in bone marrow cells of animals, usually rodents (rats, mice and Chinese...
OECD 476: In Vitro Mammalian Cell Gene Mutation Test (Mouse Lymphoma Assay) Determine if a compound is mutagenic by using cultured mammalian cells.

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OECD 487: In Vitro Mammalian Cell Micronucleus Test Assess whether a test substance induces chromosomal changes in cultured cells.

Safety Pharmacology

CNS Behavioral Measure safety toxicology effects of CNS and behavioral drugs.
Immunotoxicity Measure effects of drugs on immune function, allergic hypersensitization and autoimmune toxicity.
Safety Pharmacology Assess the impact of a therapeutic for human use on vital organ systems before first-in-man drug testing.
Tissue Cross Reactivity Assess the toxic effects of humanized monoclonal antibodies in 33 normal types recommended by the FDA.

Specialty Dosing Routes

Dermal Toxicology Assess toxicity in rodent dermal testing models.
Inhalation Toxicology Measure toxicity by daily clinical observation, body weight, clinical chemistry, hematology, and terminal necropsy and pathology.
Ophthalmologic Toxicology Measure toxicity by microscopy, vitrectomy, tonometry, electroretionography and corneal colorimetry.

Target Animal and Human Food Safety

Toxicity Test for Veterinary Drugs Use the drug at 10X the recommended dose for 3X the recommended duration to evaluate its safety.

Testing Services

Accelerated Stability Determine shelf life of drug formulations by comparing API breakdown at elevated temperature.
Bacterial Identification Testing Use biochemical and molecular methods to identify unknown microorganisms.
Bacterial Reverse Mutation Assay Test whether a cosmetic product or ingredient causes DNA mutations in bacteria.
Consumer Care Testing and Substantiation Test personal care products using analytical, in vitro, and microbial test services
Cosmetic Preservative Efficacy Test Assess the efficacy of a product's preservative system.
Cosmetics Aerobic Plate Count Determine the level of aerobic bacteria present in a cosmetic or personal care product.

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Cosmetics Yeast and Mold Count Determine the presence of fungi in a cosmetic or personal care product.
Elevated Temperature Stability Determine the stability of a product at elevated temperature.
Ex Vivo Eye Irritation Test (EVEIT) Use optical coherence tomography (OCT) to monitor full-thickness recovery of corneal tissue.
Human Eye Instillation Test Assess the eye irritation potential of a product compared with a marketed control product.
Microbiological Sterility Testing Test the presence of viable microorganisms.
Ocular Corrosion Testing Use in vitro models to determine whether a product (or ingredient) can cause ocular corrosion.
Ocular Irritation Test Use human subjects to determine whether a cosmetic product or ingredient can cause ocular irritation.
OECD 435: Skin Corrosion Test - Membrane Barrier Method Use in vitro models to determine whether a cosmetic product or ingredient can cause skin corrosion.
OECD TG 492: Ocular Irritation Testing Use in vitro skin models to determine whether a product can cause dermal sensitization (e.g. EpiOcular Eye Irritation Test - EIT)
Package Compatibility Tests Ensure that the consumer product is not adversely affected by the package components and vice versa.
PAO Stability Trial Assess the stability of a consumer product under certain storage conditions.
Raw Material Microbiological Testing Examples of which include Microbial Content using USP <61> and <62> and other standards, LAL Endotoxin, Ames Mutagenicity and Sterility.
Real-time Stability Test Assure stability and physical integrity of consumer products in real-time conditions.
Single Ocular Instillation Test Determine if a “tear-free” claim can be substantiated for a cosmetic product.
SPF Protection Efficacy Evaluation using FDA Final Rule (2011), Cosmetics Europe (COLIPA), ISO 24444
Stain Removal & Whitening Studies Assess the stain removal effectiveness of a tooth whitening product in healthy volunteers.
USP 51 Cosmetic Preservative Efficacy Test Evaluate the antimicrobial stabilization of a cosmetic product as per USP 51.
USP <61> Microbial Limits Test Determine whether a substance or preparation complies with an established specification for microbiological quality.
USP <62> Microbial Limits Test Determine the presence or absence of specific microorganisms.

Other services

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Service areas:

Pharmacology Other

United States Allegheny, Baltimore, Bismarck, Boulder, Columbus, Cortland and 21 more 28 sites

Microbac Laboratories offers material testing, microbial limits, testing services, spectroscopy, nutritional testing, and chromatography.

Professional associations: SOT
Website: www.microbac.com

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