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Unchained Labs

Unchained Labs is listed as a mid sized business research supplier in the Scientist.com network, with 1 site in 1 country.

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Sites 1
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Mid sized business

Agricultural Sciences Research & Development

  • Vaccines Testing transgenic plants as promising systems for vaccine production.

Antibodies

  • Antibody Products Purchase antibody, antibody pair kit or ELISA kit.
  • Epitope Mapping Map the antibody-antigen binding region to define protein-protein interaction sites.
  • Polyclonal Antibody Production Generate polyclonal antibodies in vivo using evolutionary distant animal species.

Cell Culture and Characterization

  • Viral Mediated Gene Delivery Use viral carriers to introduce new genetic material into a cell.

Chemical and Compound Analysis

  • Differential Scanning Calorimetry Elucidate the thermodynamics associated with conformational transitions.
  • Dynamic Light Scattering Determine the size of particles and extent of molecular aggregation in a suspension.
  • Particle Size Analysis Measure particle size distribution and characterize particle size, porosity and composition.
  • Protein Melting Point Analysis Assess protein stability by Differential Scanning Calorimetry (DSC) or Fluorimetry (Thermofluor) methods.
  • Static Light Scattering Use scattered light intensity to determine the average molecular weight of biopolymers.

Chemistry, Manufacturing and Controls (CMC)

  • Drug Formulation Combine substances including the active drug into a final product with the desired metabolic and therapeutic properties.
  • Drug Product Stability Use accelerated stress conditions to determine degradation pathways and identify manufacturing issues.
  • Excipients Acquire synthetic or natural inert components to formulate therapeutic agents.
  • Thermal Analysis Characterize compounds based on calorimetry and thermodynamic data.
Show all 30 services 16 more

Disease Models

  • Hepatitis B Virus Models Measure therapeutic endpoints in animal models of Hepatitis B virus infection.
  • Hepatitis C Virus Models Measure therapeutic endpoints in animal models of Hepatitis C virus infection.
  • Malaria Models Measure therapeutic endpoints in animal models of malaria.

In Vitro ADME

  • Red Blood Cell (RBC) Partitioning (Blood/Plasma Ratio) Measure the distribution of a compound between red blood cells and plasma.

In Vitro Assays

  • Antivirals Measure anti-viral activity in biochemical and cell assays.
  • Reporter Virus Particles (RVPs) - Dengue Neutralization Assay Use Dengue Reporter Virus Particles to measure neutralizing antibodies against each of the four Dengue serotypes.

In Vitro Pharmacology

  • High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.

Other Specialty Toxicology

  • Viral Testing Characterize viral products for functional activity and possible contamination.

Protein Sciences

  • Adeno Associated Virus (AAV) Production Clone into AAV expression vectors and produce high titer viruses.
  • Large Scale Protein Production Produce large amounts of protein using fermentors, wave mixers, bioreactors, and large-scale purification workflows.
  • Peptide Array Use biologically active synthetic peptides arranged in a high density format to assess protein interaction.
  • Peptide/Protein Based Vaccine Production Create a peptide or protein antigen for use in artificial immunization.
  • Proteomics Do large-scale experimental analysis of proteins focused on understanding structure and function.
  • Recombinant Proteins Use recombinant DNA to produce proteins in vivo or in vitro.
Show all 7 in Protein Sciences 1 more
  • Virus Production Produce high titer viruses, viral expression vectors and vaccines.

Testing Services

  • Accelerated Stability Determine shelf life of drug formulations by comparing API breakdown at elevated temperature.

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • United States Pleasanton 1 site

Source: Scientist.com supplier network (site locations)

Supplier diversity

SAM.gov small-business designations

Veteran-owned

US small-business federal-contractor designation, self-certified in the U.S. federal System for Award Management (SAM.gov). Coverage is limited to matched U.S. small-business suppliers, so an absent designation is not evidence of its absence.

Source: U.S. federal System for Award Management (SAM.gov), self-certified by the supplier

Get the Unchained Labs report as a PDF

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Sources: Scientist.com supplier network, U.S. federal System for Award Management (SAM.gov).

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