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SpiroChem AG
SpiroChem AG is listed as a small business research supplier in the Scientist.com network, with 3 sites in 2 countries.
View SpiroChem AG on Scientist.com
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Sites
3
Countries
2
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Agricultural Sciences Research & Development
- General Agrochemical Compound Library Find potential compound candidates for agrochemical or agro-product research and development.
Chemical and Compound Analysis
- Chemical Stability Measure the stability of small molecules in solution.
- Differential Scanning Calorimetry Elucidate the thermodynamics associated with conformational transitions.
- High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
- NMR Methods Use nuclear magnetic resonance spectroscopy to identify drug intermediates.
- NMR Structure Determine molecular structure, identify chemical impurities and validate sample integrity.
- Solution Nuclear Magnetic Resonance Identify molecular structure or impurities and assess product integrity of solution samples.
Show all 7 in Chemical and Compound Analysis
- Structural Elucidation Determine chemical structure of a compound. Characterization techniques include mass spectrometry, infrared spectroscopy and X-ray crystallography.
Chemistry, Manufacturing and Controls (CMC)
- API manufacturing process development, tech transfer and validation API manufacturing process development, tech transfer and validation
- Bulk Manufacturing Find facilities for large-scale mass production.
- Bulk Raw Materials Acquire raw materials in large volumes at wholesale pricing.
- Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
- Thermal Analysis Characterize compounds based on calorimetry and thermodynamic data.
Show all 53 services
Discovery Chemistry
- Building Blocks Find chemicals used for creating new compound chemotypes and HTS libraries.
- Compound Docking Identify potential compound hits based on the 3D structure of a target protein.
- Compound Management Buy, maintain and process compound libraries, natural product libraries and building blocks.
- Compound Purchase Buy compounds, building blocks or compound libraries.
- Compound Synthesis Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
- Compound Synthesis Services (IP-sensitive) Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
Show all 28 in Discovery Chemistry
- Custom Building Blocks Find or synthesize mg to kg amounts of chemical building blocks, scaffolds and reactive intermediates.
- Custom Synthesis Find or synthesize mg to kg amounts of target-specific and target agnostic compounds for HTS and biological screening.
- Discovery Computational Chemistry Model the interaction of a drug candidate with protein targets such as kinases, GPCRs, receptors, ion channels or enzymes.
- Fragment Libraries Find fragment libraries for screening against a protein or cellular target.
- Hit to Lead (H2L) Evaluate, perform limited optimization and identify small molecule hits from high throughput screens.
- HTS Libraries Find targeted and broad collections of chemical compounds for high throughput screening and ADMET applications.
- Impurity Synthesis Use high resolution MS or NMR to eliminate intermediates or organic byproducts and determine impurity content.
- LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
- Lead Optimization Perform chemical structural changes to improve preclinical drug candidate.
- Library Design & Evaluation Use structural knowledge to design target-focused compound libraries for screening.
- Method Development and Validation Develop and validate methods for synthesis and scale up of drug candidates.
- Pharmaceutical Research Chemicals Acquire chemicals that are prospective new drug entities.
- Pharmacophore Modeling Use computer models to identify hits based on structural similarity to known active compounds.
- QSAR Analysis Develop quantitative structure–activity relationship models for drug design.
- Radiochemical Synthesis Radiolabel small molecules, peptides, cytotoxics or antibody drug conjugates for DMPK analysis.
- Stable Isotope Synthesis Label drug candidates with stable isotopes that simplify compound tracking and distribution studies.
- Structure Activity Relationship (SAR) Analyze the relationship between the structure of a compound and its biological activity.
- Structure Property Relationship (SPR) Determine the functionality of a compound through the analysis of it's structure.
- Target-Focused Compound Libraries Find activity-based libraries directed towards a protein or cell signaling target.
- Trace Elemental Analysis Identify organic and inorganic elements in foods and dietary supplements at ppm to sub-ppt levels.
- UV and IR Profiling Analyze the integrity of a compound or large biomolecule.
- Virtual Screening Use software algorithms to virtually screen millions of potential compounds and peptides for binding.
Drug Development
- Chemoinformatics Consulting The use of computer and informational techniques applied to a range of problems in the field of chemistry.
- Medicinal Chemistry Consulting Apply chemistry training to the process of synthesizing new pharmaceuticals.
In Vitro ADME
- Isotopic Labeling Track labeled isotopes through a metabolic pathway or cell by measuring mass, vibrational mode or radioactive decay.
- Metabolite Quantification Quantify drug metabolites formed after drug administration to an animal model or patient.
- Metabolite Structural Elucidation Use analytical tools to characterize metabolite structure.
- Metabolite Synthesis Synthesize drug metabolites that are formed after administration of drug to an animal model or patient.
Protein Sciences
- Peptide Derivatives Acquire chemicals that are peptide derivatives.
- Peptide Synthesis Synthesize custom peptides that are long, have unusual modifications or are cyclic.
Raw Materials
- Adjusters Adjust the pH of a finished product with Spectrum's wide selection of cosmetic pH adjusters. These chemical ingredients maintain the stability of formulations and efficacy of the finished cosmetic or personal care...
- Non-Surfactant Modify the interface between solid particles and the liquid medium to improve the particles' resistance to settling.
- Plasticizers Excipients designed to modify the physical properties of a basic polymer.
Other services
- New Request
Where it operates
Sites by country, with the cities in each.
-
Switzerland 2 sites
-
Canada 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
SpiroChem AG is a Swiss CRO specialized in the design and commercialization of novel building blocks for drug discovery and in custom services for the design and the synthesis of your target molecules from milligram to kilogram-scale.
With a unique repertoire of molecular fragments along with cutting-edge know-how in drug design & process chemistry, we are the ideal collaboration partner for pharmaceutical, agrochemical and life science companies.
It is all about chemists interacting with fellow chemists at SpiroChem!
- Professional associations
- ACS
- Website
- spirochem.com
Work with SpiroChem AG on Scientist.com
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