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Research supplier
CIRCE Crystal Engineering
CIRCE Crystal Engineering is listed as a new startup research supplier in the Scientist.com network, with 2 sites in 1 country.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: New startup
Chemical and Compound Analysis
- Chemical Stability Measure the stability of small molecules in solution.
- Dissolution Profiling Measure release of API from formulation (tablet or capsules) under GMP guidelines.
- Excipient Compatibility Test excipients for drug formulation, effects of temperature, time, humidity, pH and light exposure as well as excipient release.
- Melting Point Use melting point analysis to characterize compounds based on calorimetry and thermodynamic data.
- NMR Structure Determine molecular structure, identify chemical impurities and validate sample integrity.
- Particle Size Analysis Measure particle size distribution and characterize particle size, porosity and composition.
Show all 8 in Chemical and Compound Analysis
- Partition Coefficient Determine lipophilicity (hydrophobicity) of compounds by measuring log P.
- Solubility Studies Analyze substances for kinetics of solubility using nephelometry and UV-Vis spectrometry.
Chemistry, Manufacturing and Controls (CMC)
- Drug Formulation Combine substances including the active drug into a final product with the desired metabolic and therapeutic properties.
- Drug Product Stability Use accelerated stress conditions to determine degradation pathways and identify manufacturing issues.
- Polymorph Screening Screen for unwanted API forms resulting from the drug formulation process.
- Salt Form Selection Use high-throughput automated arrays to combine APIs with multiple salts and ions to optimize formulation.
- Thermal Analysis Characterize compounds based on calorimetry and thermodynamic data.
Discovery Chemistry
- Activity Prediction Identify possible chemical hits based on the known three-dimensional structure of a protein.
- Discovery Computational Chemistry Model the interaction of a drug candidate with protein targets such as kinases, GPCRs, receptors, ion channels or enzymes.
- LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
- UV and IR Profiling Analyze the integrity of a compound or large biomolecule.
- Virtual Screening Use software algorithms to virtually screen millions of potential compounds and peptides for binding.
Show all 19 services
Other services
- New Request
Where it operates
Sites by country, with the cities in each.
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Spain 2 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
CIRCE (Center for Intelligent Research in Crystal Engineering) is a company specialized in polymorphism and pharmaceutical cocrystals. We design and perform experimental screenings in order to find new polymorphs, salts and cocrystals of Active Pharmaceutical Ingredients by combining the newest technologies and facilities in the field together with an innovative virtual prediction methodology. Our team is composed by scientists from the University of Sheffield and the University of Barcelona (UK / Spain) with a large experience in areas such as crystal engineering and supramolecular...
Show the full description
CIRCE (Center for Intelligent Research in Crystal Engineering) is a company specialized in polymorphism and pharmaceutical cocrystals.
We design and perform experimental screenings in order to find new polymorphs, salts and cocrystals of Active Pharmaceutical Ingredients by combining the newest technologies and facilities in the field together with an innovative virtual prediction methodology.
Our team is composed by scientists from the University of Sheffield and the University of Barcelona (UK / Spain) with a large experience in areas such as crystal engineering and supramolecular chemistry obtained through academic research projects and collaboration with the pharmaceutical industry. Our work is always carried out in close collaboration with the client’s researchers, adapted to the customer’s needs and under strict confidentiality conditions.
- Website
- circecrystal.com
Work with CIRCE Crystal Engineering on Scientist.com
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