Supplier site
Group of sites (click to zoom)

Scientist.com supplier network (site locations)

Research supplier

Pharmaron

Pharmaron is listed as a large business research supplier in the Scientist.com network, with 15 sites in 3 countries and 5 service areas.

View Pharmaron on Scientist.com

Email me this page as a PDF

Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 15

Countries 3

Type of company: Large business

Agricultural Sciences Compliance and Quality Control Measures

Production and Preservation Assistance with the transfer of primary products to end consumer.
Residue Chemistry Pesticide residue and tolerance testing.

Agricultural Sciences Research & Development

Agrochemical Identification Product identification and composition of pesticides; which includes fungicides, insecticide, herbicides and nematicides analysis.
Bacteriology PCR and MS-Based Bacterial Identification
Soil Science Test for microbial inoculants that promote plant health

Antibodies

Antibody based Assay Development Create specific and sensitive assays for the immunodetection of disease-specific target antigens.
Antibody Detection Quantitate, localize and visualize proteins and other antigens.
Antibody Humanization Increase an antibody's similarity to a variant produced naturally in humans.
Antibody Protein De Novo Sequencing Sequence antibody proteins using multiple enzyme digestion and high-resolution LC-MS/MS.
Antibody-Dependent Cell-Mediated Cytotoxicity Request services related to cell-mediated immune defense.
Antibody-Drug Conjugation Improve therapeutic properties of an antibody or drug by joining them together.

Show all 11 in Antibodies 5 more

Antigen Specific T-cells T cell lines that recognize specific peptide antigens to enable analysis of T cell immunity.
Immunodetection Use antibodies to identify a protein or antigen.
In Vitro Monoclonal Antibody Production Generate monoclonal antibodies in vitro using cultured antibody-secreting hybridoma cell lines.
Polyclonal Antibody Production Generate polyclonal antibodies in vivo using evolutionary distant animal species.
Polyclonal/Monoclonal Antibody Production Generate polyclonal or monoclonal antibodies in a range of animal species, over-express antibodies in cultured cells.

Bioimaging

In Vivo Whole Tissue and Animal Imaging Visualize, analyze and track light producing reporters in whole animals.
Mass Spectrometry Imaging Visualize the spatial distribution of molecules, as biomarkers, metabolites, peptides or proteins by their molecular masses

Show all 416 services 403 more

Biomarkers

Basic Metabolic Profiling Set up assays that monitor drug metabolite formation after administration of drug to an animal model or patient.
Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
Cell Migration Assays Measure chemotaxis, haptotaxis, transmigration and wound-healing.
Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
Cerebrospinal Fluid Analysis Use CSF to detect or monitor a variety of nervous system diseases or conditions.
Clinical Chemistry Measure analytes in serum, plasma, cells, tissue lysates or other biological materials.

Show all 21 in Biomarkers 15 more

Customized Primary Cell Isolation Plan and execute the isolation of primary cells from a specific biosample.
Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
Diagnostic Biomarkers Discovery Identify candidate biomarkers indicative of the presence of a disorder.
Endocrine Assays Use biochemical, cell based or in vivo assays to measure the concentration of hormones.
Epigenetics Epigenetics sits at the cutting edge of drug discovery. The ability to modify genomes without changing any sequences with methylation.
Histopathology Evaluate slide preparation of cells or tissues for abnormal features.
Human Primary Cell Isolation Isolate primary cells from various human tissues.
Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
Immunohistochemistry Examine the toxic effects of pre-clinical compounds in small animal and patient histological samples.
Lipid Kinase Assays Use biochemical, cell-based or in vivo assays to measure lipid kinase activity.
Pharmacodynamic Biomarkers Discovery Identify candidate biomarkers indicative of the therapeutic outcome of a drug-target interaction.
Protein Bioanalysis Quantitative measurement of xenobiotics (drugs and their metabolites, and biological molecules in unnatural locations or concentrations) and Proteins in biological systems
Single Cell Isolation Isolate single cells for subsequent single-cell analysis.
Single Cell quantitative Real Time-PCR Assess gene expression levels and patterns in a single cell.
Stem Cell Analysis Assess hematopoietic, neural and mesenchymal cell progenitor proliferation and differentiation.

Cell Culture and Characterization

3D Cell Culture Use a scaffold-based or scaffold-free format to grow three dimensional cell and tissue structures.
Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
Cell and Tissue Histology Prepare and stain frozen, fixed and embedded (FFPE) tissue samples.
Cell Culture Culture primary or immortalized cell lines.
Cell Line Construction Create new recombinant cell lines to exact specifications.
Cell Sorting The purpose of cell separation is to isolate a cell population from other cells in a biological sample.

Show all 9 in Cell Culture and Characterization 3 more

Cell Transfection Produce, package and optimize transfection of your siRNA or DNA construct.
Cryo-based Histology Perform sectioning and histological analysis of frozen non-fixed samples.
Histology Examine by microscopy the anatomy of cells and tissues of clinical patients and animal models.

Chemical and Compound Analysis

Accelerator Mass Spectrometry Detect trace levels of naturally-occurring radionuclides and stable nuclides.
Analytical Separations and Purification Analytical Separation and Purification of compound/molecule.
API Physical Characteristics Characterize physical and chemical properties of new drug molecules to develop safe, effective, and stable dosage forms.
Compound Integrity Analyze the identity and purity of small molecule drug candidates.
Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.

Show all 23 in Chemical and Compound Analysis 17 more

GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
Liquid Chromatography Separate substances using a mobile and stationary phase.
MALDI-TOF Analysis Use mass spectrometry technique to analyze compound, biomolecules and large organic molecules.
Nano-High Performance Liquid Chromatography Separate and detect low levels of analytes.
NMR Methods Use nuclear magnetic resonance spectroscopy to identify drug intermediates.
NMR Structure Determine molecular structure, identify chemical impurities and validate sample integrity.
Non GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Partition Coefficient Determine lipophilicity (hydrophobicity) of compounds by measuring log P.
Protein Binding HPLC Uses high pressure liquid chromatography to separate protein-drug complexes.
Protein Crystallization Create high quality protein-ligand crystals for x-ray diffraction studies.
Protein Separation and Detection Separate proteins based on properties such as solubility, adsorption or size differences.
Sample Bioanalysis Determination of concentration of an analyte in biological sample.
Solubility Studies Analyze substances for kinetics of solubility using nephelometry and UV-Vis spectrometry.
Structural Elucidation Determine chemical structure of a compound. Characterization techniques include mass spectrometry, infrared spectroscopy and X-ray crystallography.
Ultrasound Tomography Use the transmission and acquisition of ultrasound waves to create a non-invasive technique for imaging.

Chemical and Compound Testing

Clinical Pathology Diagnose disease based on the laboratory analysis of bodily fluids, such as blood, urine and tissues.

Chemistry, Manufacturing and Controls (CMC)

Advanced intermediates Sourcing advanced intermediates
Analytical Development and Validation Request services related to Analytical Development and Validation
API and Drug Product Stability Testing API and Drug Product Stability Testing.
API and drug product storage and release API and drug product storage and release
API manufacturing process development, tech transfer and validation API manufacturing process development, tech transfer and validation
API/ Excipients Compatibility Studies Delineate real and possible interactions between potential formulation excipients and the API as an important risk reduction exercise early in formulation development.

Show all 25 in Chemistry, Manufacturing and Controls (CMC) 19 more

Bi-specific Antibodies Create a protein made of fragments of two monoclonal antibodies that bind to different antigens.
Bulk Manufacturing Find facilities for large-scale mass production.
Bulk Raw Materials Acquire raw materials in large volumes at wholesale pricing.
Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
Clinical supply management Clinical supply management
Crystallization studies Crystallization studies
Drug Formulation Combine substances including the active drug into a final product with the desired metabolic and therapeutic properties.
Drug Product Stability Use accelerated stress conditions to determine degradation pathways and identify manufacturing issues.
Drug Substance and Drug Product Characterization and Manufacturing Drug Substance and Drug Product Characterization and Manufacturing.
Excipients Acquire synthetic or natural inert components to formulate therapeutic agents.
Fill and Finish Processing Confirm final product sterility, formulation and packaging in the biopharmaceutical process.
GMP Synthesis Synthesize APIs including small molecules, formulations and protein-based drugs under GMP compliance.
IND Enabling Package Request a package of Investigational New Drug (IND) Enabling Studies from our group of trusted suppliers that have enrolled in our IND-Enabling Package Program.
Integrated Antibody Development Package-Europe Process an entire Antibody Development Pipeline Project including: Antigen Synthesis, Antibody Generation, Antibody Characterization, Antibody Modification, Antibody Purification, Antibody Products from our bundle...
Milling, grinding, spray-drying Milling, grinding, spray-drying
Powder Filling Use manual, automatic or semi-automatic machinery to package a variety of powder and granules.
Regulatory Starting Materials Sourcing regulatory starting materials (RSM)
Tablet Manufacturing Use automatic or semi-automatic machinery to create various standard and non-standard tablets.
Thermal Analysis Characterize compounds based on calorimetry and thermodynamic data.

Clinical Consulting

Regulatory Consulting Ensure that each product or device complies with all FDA rules and regulations.

Clinical Trials

Bioequivalence Studies Assess the expected biological equivalence of two proprietary preparations of a drug.
IP Returns & Destruction Return the used and unused IP to the clinical trial sponsor for destruction, as well as send the used and unused IP for destruction in accordance with institution policy, or the standard operational procedure. Theses...
Mass Balance Studies Design a study to determine the mass balance of drug-related material occurring administration of dose, the ratio of parent drug metabolite(s) in circulation, and the primary route of excretion of drug-related material.
Pharmacokinetic Studies Design a study that observes the time course of drug absorption, distribution, metabolism, and excretion, as means to test the safety and effective therapeutic management of drugs in an individual patient.

Data Science/Bioinformatics

Discovery In Silico Drug Dynamics Develop In Silico model of a drug candidate with a biological system with applications such as Pro-drug Predictions, ADME-PK Due Diligence, Brain-Barrier Permeability Simulation, Drug Absorption Simulation, In Silico...
In Silico Cancer Genomics/Cancer Transcriptomics Analysis Interpret DNA sequencing and microarray data for cancer studies.

Developmental and Reproductive Toxicology (DART)

Bioelectronics Evaluate an application (e.g. device) that integrates biological materials and micro and nano-electronics.
Embryo-Fetal Development (EFD) Study (Segment II) Test drug candidate in Segment II toxicology services.
Enhanced Pre/Post-Natal Development Study (ePPND) - Monkey / Non-human Primate Conduct a study that combines in utero and postnatal assessments of your compound in monkeys/non-human primates.
Reproductive Toxicology Study adverse sexual function and fertility and examine teratogenicity of compounds.

Discovery Chemistry

Compound Docking Identify potential compound hits based on the 3D structure of a target protein.
Compound Management Buy, maintain and process compound libraries, natural product libraries and building blocks.
Compound Synthesis Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
Compound Synthesis Services (IP-sensitive) Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
Custom Building Blocks Find or synthesize mg to kg amounts of chemical building blocks, scaffolds and reactive intermediates.
Custom Synthesis Find or synthesize mg to kg amounts of target-specific and target agnostic compounds for HTS and biological screening.

Show all 20 in Discovery Chemistry 14 more

Discovery Computational Chemistry Model the interaction of a drug candidate with protein targets such as kinases, GPCRs, receptors, ion channels or enzymes.
Fragment Libraries Find fragment libraries for screening against a protein or cellular target.
Hit to Lead (H2L) Evaluate, perform limited optimization and identify small molecule hits from high throughput screens.
HTS Libraries Find targeted and broad collections of chemical compounds for high throughput screening and ADMET applications.
Impurity Synthesis Use high resolution MS or NMR to eliminate intermediates or organic byproducts and determine impurity content.
Large Scale Purification Purify gram to kilogram amounts of recombinantly-expressed or wild-type proteins.
LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
Lead Optimization Perform chemical structural changes to improve preclinical drug candidate.
Pharmacophore Modeling Use computer models to identify hits based on structural similarity to known active compounds.
QSAR Analysis Develop quantitative structure–activity relationship models for drug design.
Radiochemical Synthesis Radiolabel small molecules, peptides, cytotoxics or antibody drug conjugates for DMPK analysis.
Stable Isotope Synthesis Label drug candidates with stable isotopes that simplify compound tracking and distribution studies.
Transporters Selectively screen for compounds with good permeability in the intestine, skin, or blood-brain barrier using drug transporter a...
Virtual Screening Use software algorithms to virtually screen millions of potential compounds and peptides for binding.

Disease Models

Acute Kidney Failure Models Measure therapeutic endpoints in animal models of acute kidney failure.
Arthritis Models Measure therapeutic endpoints in animal models of arthritis.
Blood Models Test for therapeutic efficacy of drug candidates in blood disorder models.
Cardiovascular Metabolics Models Measure therapeutic endpoints in animal models of cardiovascular disorders.
Cardiovascular Models Test the therapeutic efficacy of drug candidates in cardiovacular disease models.
Cataract Models Measure therapeutic endpoints in animal models of cataracts.

Show all 25 in Disease Models 19 more

Chronic Kidney Disease Models Measure therapeutic endpoints in animal models of chronic kidney disease.
Dermatology Models Measure therapeutic endpoints in animal models of dermatological disorders.
Diabetic Retinopathy Models Assess therapeutic efficacy of drug candidates in diabetic retinopathy models of disease.
Dry Eye Models Measure therapeutic endpoints such as tear induction, TBUT, Schirmer strips (tear volume) and cornea staining.
Hematopoiesis Models Measure therapeutic endpoints in animal models of hematopoiesis.
Infectious Disease Models Test therapeutic efficacy of drug candidate in infectious disease model.
Inflammation Models Measure therapeutic endpoints in animal models for inflammation.
Inflammatory Pain Models Measure therapeutic endpoints in animal models of inflammatory pain.
Ischemia Models Measure therapeutic endpoints in animal models of ischemia.
Macular Degeneration Models Use a single animal species to create one or more models for eye disease.
Obese Mice Use a single animal species to create one or more disease models for diet-induced obesity and type II diabetes.
Ocular Inflammation Models Measure ocular inflammation in models of eye disorders such as uveitis and keratitis.
Ophthalmic Models Test drug candidates in glaucoma, macular degeneration, keratitis, uveitis and CMV retinitis models.
Receptor Binding Models Measure the binding and distribution of drugs and biologics in animal tissues.
Respiratory Models Test therapeutic efficacy of drug candidate in respiratory disease model.
Stroke Models Measure therapeutic endpoints in animal models of stroke.
Thrombosis Models Measure therapeutic endpoints in animal models of thrombosis.
Wound Healing Models Measure therapeutic endpoints in animal models of wound healing.
Xenografts Evaluate drug candidate in tissue graft or organ transplant model.

DNA & RNA

cDNA library construction Generate a library of recombinant cDNA clones.
ChIP-Sequencing Use chromosome immunoprecipitation to identify DNA-protein binding sites in a genome.
CRISPR Using advanced CRISPR technology, add or delete base pairs at a specifically targeted DNA loci.
DNA Sequencing Determine the nucleotide sequence of DNA samples.
Knockout/Knockin Cell Lines Develop Knockout/Knockin Cell Line.
NGS: Next Generation Sequencing Sequence millions of template DNA molecules in parallel.

Show all 14 in DNA & RNA 8 more

Plasmid DNA Preparation and Extraction Prepare plasmid DNA starting from E. coli cell pellets, transformed colonies or DNA samples.
qPCR Analysis Measure the accumulation of PCR products in real time.
Quantitative RT PCR Use quantitative reverse transcription polymerase chain reaction to measure absolute and relative mRNA abundance.
RNA Amplification Produce RNA from pre-clinical and clinical samples for use in gene expression studies.
RNA oligo synthesis Design and synthesize miRNAs, siRNAs and other non coding RNAs
RNA Sequencing Use Next Generation Sequencing techniques to Identify RNA transcripts, examine differential expression patterns and analyze splice variants.
shRNA Synthesis Design shRNA constructs that produce stable knockdown of the corresponding mRNA.
siRNA Synthesis Produce high quality siRNAs for gene silencing studies.

Drug Development

Chemistry, Manufacturing and Controls (CMC) Consulting Consultant services related to the development of pharmaceutical and biopharmaceutical drug products that are consistently effective, safe and high quality for consumers.

Farm & Livestock Solutions

Serology/Immunology Testing for BSE/TSE

General in vivo Toxicology

Dose Range Finding Study - Dog /Canine Conduct a study to determine the dose range of your compound in dogs/canines.
Dose Range Finding Study - Other Species Conduct a study to determine the dose range of your compound in other species.
Dose Range Finding Study - Rat Conduct a study to determine the dose range of your compound in rats.
General Toxicology Use in vivo models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.
IV Toxicology Test the toxicological effect of IV delivery of drug candidate.
Mammalian Toxicology Use toxicity testing models to carry out required FDA or REACH safety testing.

Show all 13 in General in vivo Toxicology 7 more

Repeat Dose Toxicity Study - Dog / Canine Conduct a repeat dose study in dogs to determine the toxicity and toxicokinetic behavior of your compound.
Repeat Dose Toxicity Study - Mouse Conduct a repeat dose study in mice to determine the toxicity and toxicokinetic behavior of your compound.
Repeat Dose Toxicity Study - Other Species Conduct a repeat dose study in other species to determine the toxicity and toxicokinetic behavior of your compound.
Single Dose Acute Toxicity Study - Dog / Canine Conduct a single dose study in Dogs and Canines to determine the toxicokinetic behavior of your compound.
Single Dose Acute Toxicity Study - Mouse Conduct a single dose study in Mice and Murines to determine the toxicokinetic behavior of your compound.
Single Maximum Tolerated Dose (MTD) Mouse Study Use mouse models to determine the MTD of a drug candidate by a single administration in a 7 day period.
Single Maximum Tolerated Dose (MTD) Rat Study Use rat models to determine the MTD of a drug candidate by a single administration in a 7 day period.

General Marketing

Database Management Software Facilitate the collection, tracking and processing of biological facts, statistics and observations.

Human Biological Samples

Custom PDX models For requesting Custom PDX models
Existing PDX models For requesting Existing PDX models
HBS: Human Biological Samples Request human biosamples including tissues, blood, serum, bone marrow, tissue microarrays, etc.
Human 3D cultures Provision of 3D culture of Human Primary Cells
Human Biofluids Acquire fresh/frozen biofluids based on patient demographics, disease stage, history and treatment.
Human Peripheral Blood Mononuclear Cells (PBMCs) Acquire fresh/frozen normal PBMCs based on patient demographics and history.

Show all 8 in Human Biological Samples 2 more

Human Primary Cells Acquire fresh/frozen human primary cells based on patient demographics, disease stage, history and treatment. Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely”...
Human Whole Blood Acquire fresh/frozen normal whole blood based on patient demographics and history.

In Vitro ADME

Blood Brain Barrier Measure movement of drugs from circulating blood to brain extracellular fluid.
Caco-2 Cell Permeability Measure passive diffusion of drugs across Caco2 cell monolayers.
Cell Permeability and Absorbance Models Cell Permeability and Absorbance Model assay.
Compound Distribution Determine the metabolic fate of a drug candidate in tissue and organs of diseased and normal animal models.
CYP Induction Detect increases in the expression of various isoforms of cytochrome P450 (CYP450).
CYP Inhibition Assay Assess the inactivation and inhibition of cytochrome P450 (CYP450) in microsomes isolated from primary human hepatocytes or liver.

Show all 38 in In Vitro ADME 32 more

CYP Isozyme Mapping Determine the isozymes of cytochrome P450 (CYP450) involved in the metabolism of a drug candidate.
Cytochrome P450s Assess the inhibition or induction of the various isozymes of cytochrome P450s by drug candidates.
Drug Distribution Studies Determine the metabolic fate of compounds within tissues, organs and plasma.
Drug Drug Interactions Determine whether a substance affects the activity of a drug when both are administered together.
Equilibrium Dialysis Measure the extent of binding of drugs to plasma proteins.
GI Fluid Stability Determine dosing and turnover of drug candidates in gastrointestinal fluids.
HT ADME (High-Throughput Absorption, Distribution, Metabolism and Excretion) Analyze the process and effects of a chemical that is ingested by an organism using an advanced technological screening process. Use for drug...
Intestinal Permeability Use Caco 2 and MCDK cells to assess mono-directional drug transport by passive diffusion in culture.
Isotopic Labeling Track labeled isotopes through a metabolic pathway or cell by measuring mass, vibrational mode or radioactive decay.
Membrane Transporters Use Caco 2 cells to assess bi-directional drug transport in the presence or absence of P-glycoprotein (P-gp) inhibitors.
Metabolic Stability Measure metabolic vulnerability to drug metabolizing enzymes using cell-free, cell-based and in vivo assays.
Metabolic Stability in Hepatocytes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver cells.
Metabolic Stability in Microsomes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver microsomes.
Metabolite Generation Analyze the formation of drug metabolites after administration of drug to an animal model or patient.
Metabolite Identification Identify drug metabolites that are formed after administration of drug to an animal model or patient.
Metabolite Identification and Profiling Estimate drug candidate metabolites after administration of drug to an animal or human subject.
Metabolite Quantification Quantify drug metabolites formed after drug administration to an animal model or patient.
Metabolite Structural Elucidation Use analytical tools to characterize metabolite structure.
Metabolite Synthesis Synthesize drug metabolites that are formed after administration of drug to an animal model or patient.
Nasal Permeability Test for passive diffusion and active transport in nasal permeability models.
No Label Methods Use mass spectrometry to detect and identify non-radiolabeled drug intermediates in pre-clinical samples.
Non Isotopic Labeling Track unlabeled macromolecules through a metabolic pathway or cell.
Ocular Permeability Measure passive diffusion and active transport of drugs across confluent ocular epithelial cells.
Phase I Metabolism Use enzymes such as cytochrome P450 oxidases to introduce reactive or polar groups into xenobiotics.
Phase II Metabolism Use transferase enzymes such as glutathione S-transferases to conjugate phase I xenobiotics to polar compounds.
Plasma Stability Assay Determine degradation rate of drug candidates in plasma.
Protein Binding Ultrafiltration Measure the rate at which unbound drug passes through a dialysis membrane that models epithelial barrier pore size.
Radiolabeled Tracers Use radiolabeled drug metabolites as radiotracers for measuring desired physiological processes.
Reactive Metabolite Ensure that your drug candidate is not generating toxic reactive metabolites in vivo.
Red Blood Cell (RBC) Partitioning (Blood/Plasma Ratio) Measure the distribution of a compound between red blood cells and plasma.
Reference Standards Find reference standards for assays, tests and services.
Skin Permeability Use human skin models to determine transdermal delivery and percutaneous absorption of pre-clinical drugs.

In Vitro Assays

Annexin V Apoptosis Assay Detect and quantify apoptotic cells based on loss of membrane asymmetry.
Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
Apoptotic Cell Staining Detect apoptotic cells in culture.
Assay Development Construct or create new assays or modify existing ones.
Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
Cell Proliferation Measure cell number, cell viability and cell division.

Show all 11 in In Vitro Assays 5 more

High Content Screening Analyze whole cells or components of cells with simultaneous readout of several parameters.
HTS Assay Development Develop assays to use in high throughput screening.
In Vitro Human Cell Assays Request in vitro human cells for assays
Luciferase Reporter Assay Evaluate promoter activity by measuring light output from the luciferase enzyme.
Phenotype Assays Measure effects of drug candidate on the morphology or function of cells and whole animals.

In Vitro Pharmacology

B-Cell Lymphoma 2 (BCL-2) Assays Use biochemical, cell based or in vivo assays to measure BCL-2 protein activity.
Cellular Thermal Shift Assay Use a novel biophysical assay for in situ drug target engagement and mechanistic biomarker studies.
Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
Extracellular signal Regulated Kinase Assays Use biochemical, cell based or in vivo assays to measure ERK enzyme activity.
G-Protein Coupled Receptor (GPCR) Assays Detect ligand binding, receptor dimerization and downstream signal transduction events.
Glucose Transporter Assays Use biochemical, cell-based or in vitro assays to measure glucose transporter activity.

Show all 30 in In Vitro Pharmacology 24 more

High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
Immuno-oncology Assays Use biochemical, cell based or in vivo assays to measure the activity of immuno-therapy targets.
Immuno-oncology Targets Develop drugs that take advantage of the immune system to target cancer cells.
In Vitro Cardiovascular Models Measure stimulation and inhibition of lipolysis, adipogenesis and endothelial cell migration.
In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
In Vitro Hepatotoxicity Assays Use in vitro assays to measure hepatoxicity-related activities.
In Vitro Neural Models Use cultured neurons, neuronal progenitor cells and stem cell differentiation to create cellular models of neurological disease.
In Vitro Oncology Models Use cell-based and biochemical models of cancer.
Ion Channels Use fluorometry, electrophysiology and radiometric binding assays to measure ion channel activity.
Kinase Assays Measure activity of over 500 kinases in biochemical or cell-based assays.
Nuclear Receptor Assays Measure nuclear receptor activity in biochemical and cell assays.
Nucleoside Transporter Assays Use biochemical, cell-based or in vivo assays to measure nucleoside transporter activity.
Peptide Transporter Assays Use biochemical, cell-based or in vivo assays to measure peptide transporter activity.
Polymerase Assays Measure polymerase activity in biochemical and cell-based assays.
Programmed Cell Death-1 (PD-1) Assays Use biochemical, cell based or in vivo assays to measure PD-1 receptor activity.
Protein Targets Protein Targets are of pharmaceutical interest for drug discovery purposes.
Raf Assays Use biochemical, cell based or in vivo assays to measure Raf enzyme activity.
RAS Assays Use biochemical, cell based or in vivo assays to measure RAS enzyme activity.
Selectivity Profiling Determine the specificity of a ligand for its target by testing it against a large panel of related target proteins.
Solute-Linked Carrier (SLC) Transporter Inhibition Assays Use biochemical, cell-based or in vivo assays to measure solute-linked carrier transporter activity.
Target Identification Identify the target(s) of a biologically active substance.
Time Dependent Study Determine whether or not a compound binds to an enzyme in a time-dependent manner.
Transporter Assays Use biochemical, cell-based or in vitro assays to measure transporter target activity.
UDP-glucuronosyltransferases (UGT) Inhibition Assays Use biochemical, cell-based or in vivo assays to measure UDP-glucuronosyltransferase activity.

In Vitro Toxicology

Cardiac Channels Measure the arrhythmia producing potential of test compounds.
Cardiotoxicity Evaluate the effect of a compound on heart electrophysiology and muscle function.
Cardiovascular Toxicology Measure the toxic effects of pre-clinical compounds.
Cytotoxicity Test for effects on cell viability and proliferation
Cytotoxicity Testing Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.
Hematopoietic Cell Toxicity Examine cytotoxic effects of pre-clinical compounds or biologics on adult stem cells.

Show all 7 in In Vitro Toxicology 1 more

hERG Inhibition Measure the arrhythmia-producing potential of test compounds.

In Vivo ADME

Absorption studies Study the factors determning how efficiently a compound may enter the bloodstream.
Chronic Bile Duct Cannulation (BDC) Study - Dog / Canine Conduct a bile duct cannulation (BDC) study in dogs/canines to support the absorption, distribution, metabolism and excretion profiling of your compound.
Chronic Bile Duct Cannulation (BDC) Study - Monkey / Non-human Primate Conduct a bile duct cannulation (BDC) study in monkeys/non-human primates to support the absorption, distribution, metabolism and excretion profiling of your compound.
Chronic Bile Duct Cannulation (BDC) Study - Other Species Conduct a bile duct cannulation (BDC) study in other species to support the absorption, distribution, metabolism and excretion profiling of your compound.
Chronic Bile Duct Cannulation (BDC) Study - Rat Conduct a bile duct cannulation (BDC) study in rats to support the absorption, distribution, metabolism and excretion profiling of your compound.
Expired Air Study - Mouse Conduct a study to collect expired air and monitor its radioactivity content in mice.

Show all 22 in In Vivo ADME 16 more

In Vivo Radiolabeled Metabolism Determine the qualitative and quantitative metabolism and/or degradation of an active ingredient in animals.
Mass Balance Study - Dog / Canine Conduct a study to investigate the plasma pharmacokinetics and excretion of your compound as well as total radioactivity in dogs/canines.
Mass Balance Study - Minipig Conduct a study to investigate the plasma pharmacokinetics and excretion of your compound as well as total radioactivity in minipigs.
Mass Balance Study - Monkey / Non-human Primate Conduct a study to investigate the plasma pharmacokinetics and excretion of your compound as well as total radioactivity in monkeys/non-human primates.
Mass Balance Study - Other Species Conduct a study to investigate the plasma pharmacokinetics and excretion of your compound as well as total radioactivity in other species.
Mass Balance Study - Rat Conduct a study to investigate the plasma pharmacokinetics and excretion of your compound as well as total radioactivity in rats.
Milk Secretion Study - Rat Conduct a study to determine the extent of milk secretion of your radioactive compound in rats.
Ocular Distribution Study - Dog / Canine Conduct a study to determine the distribution of your compound in ocular tissues of the dog/canine.
Ocular Distribution Study - Monkey / Non-human Primate Conduct a study to determine the distribution of your compound in ocular tissues of the monkey/non-human primate.
Ocular Distribution Study - Other Species Conduct a study to determine the distribution of your compound in ocular tissues of other species.
Ocular Distribution Study - Rabbit Conduct a study to determine the distribution of your compound in ocular tissues of the rabbit.
Ocular Distribution Study - Rat Conduct a study to determine the distribution of your compound in ocular tissues of the rat.
Quantitative Whole Body Autoradiography (QWBA) Determine the tissue distribution of a radiolabeled compound in Rodent and Non-Rodent Species.
Quantitative Whole Body Autoradiography (QWBA) - Non-rodent Species Conduct a study to determine the tissue distribution of your compound radiolabeled compound in non-rodent species.
Quantitative Whole Body Autoradiography (QWBA) - Rodent Species (Mouse, Rat) Conduct a study to determine the tissue distribution of your compound radiolabeled compound in rodent species.
Tissue Distribution Study the tissues in which a compound or its metabolites, accumulate.

In Vivo Pharmacokinetics

In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
Integrated In Vivo Services Package Process an entire In Vivo Project including: Dose Formulation, PK Screening, ADME-Profiling, Toxicology, Safety Pharmacology, DART, IND Filing from our bundle of suppliers.
Mass Balance Elucidate excretory pathways and organ distribution of a parent drug and metabolites
Maximum Tolerated Dose (MTD) Studies Determine Maximum Tolerated Dose (MTD) of a drug candidate in either a single or repetitive dosing study in a rodent (typically mouse or rat).
Ocular Pharmacokinetic (PK) Screening - Dog / Canine Conduct a pharmacokinetic screening study in dogs/canines that measures the absorption, distribution, metabolism and excretion of your compound following ocular administration.
Ocular Pharmacokinetic (PK) Screening - Monkey / Non-human Primate Conduct a pharmacokinetic screening study in monkeys/non-human primates that measures the absorption, distribution, metabolism and excretion of your compound following ocular administration.

Show all 19 in In Vivo Pharmacokinetics 13 more

Ocular Pharmacokinetic (PK) Screening - Other Species Conduct a pharmacokinetic screening study in other species that measures the absorption, distribution, metabolism and excretion of your compound following ocular administration.
Ocular Pharmacokinetic (PK) Screening - Rabbit Conduct a pharmacokinetic screening study in rabbits that measures the absorption, distribution, metabolism and excretion of your compound following ocular administration.
Ocular Pharmacokinetic (PK) Screening - Rat Conduct a pharmacokinetic screening study in rats that measures the absorption, distribution, metabolism and excretion of your compound following ocular administration.
Pharmacokinetic (PK) Screening Measure the absorption, distribution, metabolism and excretion of a compound.
Pharmacokinetic (PK) Screening - Dog / Canine Run pharmacokinetic studies in dogs that measure a drug’s absorption, distribution, metabolism and excretion.
Pharmacokinetic (PK) Screening - Minipig Run pharmacokinetic studies in minipigs that measure a drug’s absorption, distribution, metabolism and excretion.
Pharmacokinetic (PK) Screening - Monkey / Non-human Primate Conduct a pharmacokinetic screening study in monkeys/non-human primates that measures the absorption, distribution, metabolism and excretion of your compound.
Pharmacokinetic (PK) Screening - Mouse Run pharmacokinetic studies in mice that measure a drug's absorption, distribution, metabolism and excretion.
Pharmacokinetic (PK) Screening - Other Species Run pharmacokinetic studies in large animals that measure a drug's absorption, distribution, metabolism and excretion.
Pharmacokinetic (PK) Screening - Rat Run pharmacokinetic studies in rats that measure a drug's absorption, distribution, metabolism and excretion.
Rat Efficacy Combination Use rat models to determine the anti-cancer efficacy and potential synergy of a drug candidate with a standard drug treatment.
Repetitive Maximum Tolerated Dose (MTD) Mouse Study Use mouse models to determine the MTD of a drug candidate by repetitive administrations for 7 days.
Repetitive Maximum Tolerated Dose (MTD) Rat Study Use rat models to determine the MTD of a drug candidate by repetitive administrations for 7 days.

Lab Supplies, Facilities, and Equipment

Biobanking Store and track biological samples.

Medical Communications

Protocol and Study Reports Write protocol and study reports, specifically relating to the drafting, writing, and editing of Clinical Safety Reports.
Publication Writing Create further publication documents. Investigational device exemptions (IDEs) BLAs, MAA, PMA, eCTDs, informed consents, CMC and manufacturing reports, orphan drug designations (ODD), briefing books.

Model Development

Custom Model Development Develop a custom disease model.
Fresh Functional Human Tissue Permeability Assays Use fresh functional human tissue to assess tissue permeability with various compounds.
Non-Human Primate Models Use a single animal species to create one or more disease models.
PBMC Humanized Mice Study and evaluate compounds for infectious diseases and graft rejection.
Pre-clinical Animal Surgery Conduct surgey in animals used as pre-clinical models.
Transgenic Models Create animal models engineered for use in a specific therapeutic area.

Nanotechnology

Nanoparticle Conjugation and Functionalization Modify biomolecules to enhance structure and function.
Nanoparticle Synthesis Create nano-level structures with unique features.

Neurotoxicology

Single Dose Acute Neurotoxicity Study - Other Species Conduct a single dose study in other species to determine the neurotoxicty of your compound.
Single Dose Acute Neurotoxicity Study - Rat Conduct a single dose study in rats to determine the neurotoxicty of your compound.

Non-Human Biospecimen

Monkey / Non-Human Primate / NHP Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
Monkey / Non-Human Primate / NHP Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.
Rat Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.

Oncology Models

Angiogenesis Models Measure therapeutic endpoints in animal models of angiogenesis.
Athymic Mouse Use a single animal species to create one or more disease models for cachexia and spontaneous cancer.
Nervous System Xenografts Xenografts relating to the Nervous system. This includes samples from the Head, Neck, Brain, and Nerves.
Oncology Derived PDX Patient derived xenografts derived from various oncological samples. This includes, but is not limited to, samples from Lymphoma, Melanoma, and Leukemia.
Oncology Models Use model organisms to test the therapeutic efficacy of cancer drug candidates.
Oncology Xenografts Xenografts derived from oncological samples.

Show all 8 in Oncology Models 2 more

Reproductive System Xenografts Xenografts relating and derived from the reproductive systems. This includes samples from the ovaries, cervix, vulva, uterus, testes, scrotum, and prostate.
Xenograft Models Measure therapeutic endpoints in cancer models using tumor cells transplanted from a donor of a different species.

Other Specialty Toxicology

Ocular Phototoxicty Study - Rat Conduct a study to determine the extent to which your compound is capable of producing phototoxic side effects in ocular tissues of rats.

Pharmacology

In Vivo Pharmacology Study the effects of drug candidates in animal models

Pharmacovigilance

GxP Compliance Monitoring Ensure products or services adhere to a set minimum standard.

Protein Sciences

Adeno Associated Virus (AAV) Production Clone into AAV expression vectors and produce high titer viruses.
Affinity Tag Purification Purify proteins under physiological conditions at their native cellular levels.
Analytical Ultracentrifugation Characterize the interactions and properties of macromolecules in solution.
Antibody-Antigen Affinity Measurement Measure the binding kinetics of an antibody–antigen interaction.
Bacterial Expression Produce milligram, gram and kilogram amounts of proteins.
Enzymology Enzymology studies the biochemical activity, structure, and function of enzymes. Two key area of Enzymology are Cytochrome P450...

Show all 28 in Protein Sciences 22 more

Fusion Proteins Use recombinant DNA technology to create and express proteins derived from more than one gene.
Host Cell Protein Analysis Measure contamination of biologics with host proteins by using sequencing, chromatography and the LAL test.
Immunoprecipitation Precipitate a protein of interest out of solution using an antibody to which it binds.
Insect Expression Use baculovirus infected cells or non-lytic cell systems to produce glycosylated proteins.
LCMS/MS Analysis Liquid chromatography–mass spectrometry is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography with the mass analysis capabilities of mass spectrometry.
Mammalian Expression Express high yields of recombinant proteins, antibodies, virus, viral-subunit proteins and gene-therapy vectors.
Mass Spectrometry-Based Proteomics Detect histone post-translational modifications (hPTMs), histone variants, and interactomes at chromatin regions.
Peptide Synthesis Synthesize custom peptides that are long, have unusual modifications or are cyclic.
Protein Binding Determine drug-protein binding interactions
Protein Conjugation Create tagged monoclonals, polyclonal and recombinant proteins.
Protein Expression Produce recombinant proteins in prokaryotic or eukaryotic systems.
Protein Identification Uncover or confirm the identity of a protein.
Protein Production Produce recombinant protein molecules in prokaryotic or eukaryotic systems.
Protein Purification Isolate native or recombinant proteins from a sample.
Protein Sequencing Determine the amino acid sequence of protein or peptide.
Qualitative MS Perform direct identification of molecules based on mass-to-charge ratio and fragmentation patterns.
Quantitative MS Quantify small and large molecules in the pg/ml range
Recombinant Proteins Use recombinant DNA to produce proteins in vivo or in vitro.
Solid Phase Peptide Synthesis Create peptides on solid supports with reduced product loss.
Surface Plasmon Resonance (SPR) Measure interactions of biomolecules including antibodies, vaccines, biomarkers and small molecules.
Western Blots Detect specific proteins in a sample of tissue homogenate or extract.
Yeast Expression Amplify eukaryotic proteins that contain post translational modifications.

Radioanalysis

Stand-alone Radioanalysis of Human Clinical Samples Conduct analysis of radioactive samples from clinical metabolism radiolabeled studies.

REACH Services

In Vivo REACH Services Performing testing when in vitro studies cannot be used to predict biological responses
OECD 405: Acute Eye Irritation/Corrosion This method provides information on health hazard likely to arise from exposure to test substance (liquids, solids and aerosols) by application on the eye.
OECD 471: Bacterial Reverse Mutation Test (Ames) Measure the mutagenic potential of test compounds.

Safety Pharmacology

Abuse and Dependence Liability Testing Determine the abuse or dependence potential of a therapeutic.
Abuse Liability Determine the dependence potential of a therapeutic.
CNS Behavioral Measure safety toxicology effects of CNS and behavioral drugs.
Immunotoxicity Measure effects of drugs on immune function, allergic hypersensitization and autoimmune toxicity.
Off Target Effects Assess toxicities by body weight, clinical chemistry, hematology, urinalysis and terminal necropsy and pathology.
Respiratory Toxicology Assess difficulty breathing, altered respiration, blood gas changes and blood pH issues due to adverse reactions.

Show all 8 in Safety Pharmacology 2 more

Safety Pharmacology Assess the impact of a therapeutic for human use on vital organ systems before first-in-man drug testing.
Target Safety Assessment Understand the role of your drug target and assess risks in normal physiology.

Scientific Data Services

In Silico Genomics/Transcriptomics Data Analysis Interpret DNA sequencing and microarray data.
Strategic RFX Utilize the Scientist.com marketplace to run a strategic RFI/RFP to consolidate orders across different sites with preferred vendors, find new vendors, and leverage to negotiate better pricing.

Specialty Dosing Routes

Dermal Toxicology Assess toxicity in rodent dermal testing models.
Inhalation Toxicology Measure toxicity by daily clinical observation, body weight, clinical chemistry, hematology, and terminal necropsy and pathology.
Intracameral Implant Toxicity and/or Toxicokinetic Study - Dog / Canine Conduct an intracameral implant toxicity study in dogs/canines to determine the toxicity and toxicokinetic behavior of your compound.
Intracameral Implant Toxicity and/or Toxicokinetic Study - Other Species Conduct an intracameral implant toxicity study in other species to determine the toxicity and toxicokinetic behavior of your compound.
Intracameral Implant Toxicity and/or Toxicokinetic Study - Rabbit, Non-pigmented (New Zealand White; NZW) Conduct an intracameral implant toxicity study in non-pigmented rabbits to determine the toxicity and toxicokinetic behavior of your compound.
Intracameral Implant Toxicity and/or Toxicokinetic Study - Rabbit, Pigmented (Dutch Belted, New Zealand Red) Conduct an intracameral implant toxicity study in pigmented rabbits to determine the toxicity and toxicokinetic behavior of your compound.

Show all 19 in Specialty Dosing Routes 13 more

Intravitreal Toxicity and/or Toxicokinetic Study - Dog / Canine Conduct an intravitreal ocular toxicity study in dogs/canines to determine the toxicity and toxicokinetic behavior of your compound.
Intravitreal Toxicity and/or Toxicokinetic Study - Minipig Conduct an intravitreal ocular toxicity study in minipigs to determine the toxicity and toxicokinetic behavior of your compound.
Intravitreal Toxicity and/or Toxicokinetic Study - Monkey / Non-human Primate Conduct an intravitreal ocular toxicity study in monkeys/non-human primates to determine the toxicity and toxicokinetic behavior of your compound.
Intravitreal Toxicity and/or Toxicokinetic Study - Other Species Conduct an intravitreal ocular toxicity study in other species to determine the toxicity and toxicokinetic behavior of your compound.
Intravitreal Toxicity and/or Toxicokinetic Study - Rabbit, Non-pigmented (New Zealand White; NZW) Conduct an intravitreal ocular toxicity study in non-pigmented rabbits to determine the toxicity and toxicokinetic behavior of your compound.
Intravitreal Toxicity and/or Toxicokinetic Study - Rabbit, Pigmented (Dutch Belted, New Zealand Red) Conduct an intravitreal ocular toxicity study in pigmented rabbits to determine the toxicity and toxicokinetic behavior of your compound.
Ophthalmologic Toxicology Measure toxicity by microscopy, vitrectomy, tonometry, electroretionography and corneal colorimetry.
Topical Ocular Toxicity and/or Toxicokinetic Study - Dog / Canine Conduct a topical ocular toxicity study in dogs/canines to determine the toxicity and toxicokinetic behavior of your compound.
Topical Ocular Toxicity and/or Toxicokinetic Study - Minipig Conduct a topical ocular toxicity study in minipigs to determine the toxicity and toxicokinetic behavior of your compound.
Topical Ocular Toxicity and/or Toxicokinetic Study - Mouse Conduct a topical ocular toxicity study in mice to determine the toxicity and toxicokinetic behavior of your compound.
Topical Ocular Toxicity and/or Toxicokinetic Study - Rabbit, Non-pigmented (New Zealand White; NZW) Conduct a topical ocular toxicity study in non-pigmented rabbits to determine the toxicity and toxicokinetic behavior of your compound.
Topical Ocular Toxicity and/or Toxicokinetic Study - Rabbit, Pigmented (Dutch Belted, New Zealand Red) Conduct a topical ocular toxicity study in pigmented rabbits to determine the toxicity and toxicokinetic behavior of your compound.
Topical Ocular Toxicity and/or Toxicokinetic Study - Rat Conduct a topical ocular toxicity study in rats to determine the toxicity and toxicokinetic behavior of your compound.

Testing Services

Accelerated Stability Determine shelf life of drug formulations by comparing API breakdown at elevated temperature.
Elevated Temperature Stability Determine the stability of a product at elevated temperature.
Freeze-Thaw Testing Use freeze-thaw cycling to measure the long-term durability of cosumer products.
In Vitro Skin Models Measure skin model penetration and invasion, photosensitivity and toxicity.
In Vitro Toxicology Testing Non-animal testing employing US and international methodologies for determining irritation and other undesirable potentials.
Membrane Permeability (PAMPA) Parallel Artificial Membrane Permeability Assay (PAMPA) - Measure passive diffusion of drugs by the parallel artificial membrane permeation assay.

Show all 8 in Testing Services 2 more

Ocular Irritation Test Use human subjects to determine whether a cosmetic product or ingredient can cause ocular irritation.
Real-time Stability Test Assure stability and physical integrity of consumer products in real-time conditions.

Other services

Human Dendritic Cell (hDC) Model Test and validate the immune-modulating compounds in DC immune pathway models.
New Request

Service areas:

Biology Chemistry DMPK Pharmacology Toxicology

China Beijing, Hangzhou Bay, Hangzhou Bay New Zone Ningbo, Ningbo, Wuxi City, Xi'an 8 sites
United States Carlsbad, Germantown, Louisville, Woburn 4 sites
United Kingdom Rushden, Cardiff 3 sites

Pharmaron's mission is to provide the highest quality R&D services while helping our customers advance their projects in a timely and cost effective manner. Chemistry: In addition to our strong synthetic chemistry team with exceptional skill in heterocyclic chemistry, Pharmaron has expertise in chiral chemistry (asymmetric chemical & enzymatic reactions) and bioorganic chemistry including nucleosides & nucleotides, carbohydrates, lipid & PEGylation chemistry. Pharmaceutical Development and Manufacturing (PDM): Our experienced chemical development group routinely designs and discovers new...

Show the full description

Pharmaron's mission is to provide the highest quality R&D services while helping our customers advance their projects in a timely and cost effective manner.

Chemistry: In addition to our strong synthetic chemistry team with exceptional skill in heterocyclic chemistry, Pharmaron has expertise in chiral chemistry (asymmetric chemical & enzymatic reactions) and bioorganic chemistry including nucleosides & nucleotides, carbohydrates, lipid & PEGylation chemistry.

Pharmaceutical Development and Manufacturing (PDM): Our experienced chemical development group routinely designs and discovers new scaleable routes, optimize existing routes for quick scale up as well as develop manufacturing routes. We have the expertise and equipment to prepare compounds from gram to hundreds of kilograms scales. We can provide GMP manufacturing of drug substances (API) on the kilogram scale as well.

Biology: Pharmaron biology provides a broad spectrum of high quality services to support various stages of drug discovery and development. With strong training in biochemistry, molecular and cellular biology, our teams are highly experienced, and focused on customer assay development, compound evaluation using cell-free biochemical assays, cell culture models, and biomarker discovery.

In Vitro ADME Services: Pharmaron offers a comprehensive panel of in vitro ADME assays including solubility, metabolic stability (microsomes, liver S9 fraction, hepatocytes), permeability, plasma protein binding, Cyp inhibition and In Vitro toxicology.
PK / Bioanalytical: Pharmaron offers comprehensive in vivo pharmacokinetic (PK), toxicokinetics, GLP bioanalytical, discovery bioanalytical, and formulation services to our partners.

In Vivo Pharmacology: Pharmaron in vivo pharmacology services include oncology, metabolic diseases, CNS, pain, inflammation and other established animal models and procedures. Our large collections of human tumor xenograft models, human tumor tissue bank and pharmacogenomic information allow partners to select and identify relevant tumor models for compounds evaluation and help accelerate their drug discovery and development process.

Preclinical Services (PCS): Pharmaron's AAALAC-accredited toxicology facility in Beijing is one of the largest vivariums in China, built from the ground up to be US GLP-compliant. All GLP studies are audited by an independent Quality Assurance Unit (QAU), comply with US FDA Good Laboratory Practices (GLP; 21CFR Part 58), and are managed with US-level animal welfare oversight.

Integrated Services: Pharmaron offers comprehensive services in all areas of drug R&D. Our ability to bring the groups together in a single project allows us to provide quality integrated R&D services.

Website: www.pharmaron.com

Minority-owned

US small-business federal-contractor designation, self-certified in the U.S. federal System for Award Management (SAM.gov). Coverage is limited to matched U.S. small-business suppliers, so an absent designation is not evidence of its absence.

Work with Pharmaron on Scientist.com

For prices, more details, or to contact Pharmaron, visit Scientist.com.

View on Scientist.com