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Reprocell
Reprocell is listed as a small business research supplier in the Scientist.com network, with 5 sites in 3 countries and 1 service area.
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Sites
5
Countries
3
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Agricultural Sciences Compliance and Quality Control Measures
- Exposure Tests which assess human health impact upon exposure of product.
- Pesticide Product Testing Use laboratory assays to evaluate the efficacy, safety and selectivity of a pesticide under GLP standards.
Biomarkers
- Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
- Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
- Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
- Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
- Propidium Iodide FACS Analysis Use DNA staining and flow cytometry to analyze the cell cycle and detect apoptosis or cell proliferation.
- Stem Cell Analysis Assess hematopoietic, neural and mesenchymal cell progenitor proliferation and differentiation.
Cell Culture and Characterization
- 3D Cell Culture Use a scaffold-based or scaffold-free format to grow three dimensional cell and tissue structures.
- Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
- Cell Line Characterization Track source history and characterize cell lines to establish identity, purity and stability.
- Cell Lines Purchase culture reagents, cell lines and cellular material of any species. Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely” Primary Cells are cells that have...
- Cell Transfection Produce, package and optimize transfection of your siRNA or DNA construct.
- Explant Culture Culture cells obtained from a part or parts of an in vivo structure.
Show all 15 in Cell Culture and Characterization
- Gene-Edited iPSCs Disease Models Use gene-edited iPSCs to model human diseases.
- Histology Examine by microscopy the anatomy of cells and tissues of clinical patients and animal models.
- Induced Pluripotent Stem (iPS) Cell Reprogramming Generate induced pluripotent stem cells from adult somatic cells.
- Isogenic Knockout iPSC Lines Mimic loss of function of genes associated with various diseases and disorders.
- Mycobacterium Screening Detect and distinguish between mycobacterium strains and species.
- Organotypic Culture Co-culture different cells to enable in vitro growth of an in vivo tissue or organ equivalent.
- RNA-Based Transfection Deliver RNA to cells by microinjection, electroporation or lipid-mediated transfection.
- Stem Cell Differentiation Acquire specialized cells from differentiated stem cells.
- Stem Cell Methodologies Study Stem Cell characteristics.
Show all 112 services
Chemical and Compound Testing
- Product Testing Ensure product quality standards are met.
Data Science/Bioinformatics
- Clinical Machine Learning/AI Complex analytical approaches to find patterns and make predictions in drug discovery projects
- Discovery Machine Learning/AI Complex analytical approaches to find patterns and make predictions in drug discovery projects.
- Translational Machine Learning/AI Complex analytical approaches to find patterns and make predictions in drug discovery projects.
Disease Models
- Cardiovascular Models Test the therapeutic efficacy of drug candidates in cardiovacular disease models.
- LPS Acute Response Models Measure therapeutic endpoints in acute models of inflammation.
- Neuroscience Models Test therapeutic efficacy of drug candidate in neurological disease model.
- Pain Models Test therapeutic efficacy of drug candidate in pain model.
- Parkinson's Disease Models Measure therapeutic endpoints in animal models of Parkinson's disease.
- Precision Cut Lung Slices (PCLS) Use a phenotypically accurate model of lung behavior for screening and target validation.
Show all 7 in Disease Models
- Respiratory Models Test therapeutic efficacy of drug candidate in respiratory disease model.
DNA & RNA
- CRISPR Using advanced CRISPR technology, add or delete base pairs at a specifically targeted DNA loci.
- DNA Mutagenesis Introduce insertions, deletions and substitutions into DNA clones.
- DNA/RNA Extraction & Purification DNA/RNA Extraction & Purification.
- Genome Editing Use CRISPR, ZFN, TALEN or AAV gene targeting for targeted gene mutations and creation of transgenics.
- Genomic DNA Purification Isolate genomic DNA from cells or tissue samples.
- Genotyping Examine a DNA sequence to identify specific genetic varients .
Show all 13 in DNA & RNA
- miRNA sequencing Identify miRNAs by Next Generation Sequencing and bioinformatic analysis.
- NGS: Next Generation Sequencing Sequence millions of template DNA molecules in parallel.
- PCR Mutagenesis Use polymerase chain reaction to create mutations in a cloned gene.
- qPCR Analysis Measure the accumulation of PCR products in real time.
- Quantitative RT PCR Use quantitative reverse transcription polymerase chain reaction to measure absolute and relative mRNA abundance.
- RNA Sequencing Use Next Generation Sequencing techniques to Identify RNA transcripts, examine differential expression patterns and analyze splice variants.
- Target Gene Expression Measure expression of a target gene at the protein, RNA and DNA level.
Drug Development
- Safety Pharmacology Consulting Consulting services that help with the detection of potential undesirable pharmacodynamic effects of chemical entities on physiological functions.
General in vivo Toxicology
- Mammalian Toxicology Use toxicity testing models to carry out required FDA or REACH safety testing.
Human Biological Samples
- Biospecimen Finder Explore listings of Human Biological Samples from the suppliers on the scientist.com HBS database
- FRBESaHBS Request human biosamples including tissues, blood, serum, bone marrow, and tissue microarrays.
- HBS Asthma For requesting HBS Asthma.
- HBS Leukemia For requesting HBS Leukemia
- HBS: Human Biological Samples Request human biosamples including tissues, blood, serum, bone marrow, tissue microarrays, etc.
- HBS: Human Biological Samples - BI STEP 1: EDIT the title above to reflect the human biospecimens you would like to order. STEP 2: If you already know the supplier you wish to use, please include them in the request form. If you have not identified...
Show all 19 in Human Biological Samples
- Human DNA Acquire human DNA.
- Human DNA & RNA Acquire fresh/frozen Human DNA & RNA based on patient demographics, disease stage, treatment and history
- Human Fresh Tissue For requesting fresh human tissue
- Human Frozen Tissue For requesting frozen human tissue.
- Human iPSC's For requesting human sourced induced pluripotent stem cells.
- Human Neural Stem Cells Acquire human neural stem cells isolated from brain tissue.
- Human Peripheral Blood Mononuclear Cells (PBMCs) Acquire fresh/frozen normal PBMCs based on patient demographics and history.
- Human Plasma Acquire fresh/frozen human plasma
- Human Primary Cells Acquire fresh/frozen human primary cells based on patient demographics, disease stage, history and treatment. Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely”...
- Human RNA Acquire fresh/frozen Human RNA based on patient demographics, disease stage, treatment and history.
- Human Whole Blood Acquire fresh/frozen normal whole blood based on patient demographics and history.
- Human Whole Blood For requesting Human Whole Blood
- SARS-CoV-2 (COVID-19) Human Biological Samples Search for available SARS-CoV-2 human biological samples
In Vitro ADME
- Cell Permeability and Absorbance Models Cell Permeability and Absorbance Model assay.
- CYP Induction Detect increases in the expression of various isoforms of cytochrome P450 (CYP450).
- CYP Inhibition Assay Assess the inactivation and inhibition of cytochrome P450 (CYP450) in microsomes isolated from primary human hepatocytes or liver.
In Vitro Assays
- 3D Cell Microscopy Assay Investigate cellular and subcellular events in three dimensional 3D cultures by using fluorescence microscopy.
- Annexin V Apoptosis Assay Detect and quantify apoptotic cells based on loss of membrane asymmetry.
- Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Cell Based Assays Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
- Cell Proliferation Measure cell number, cell viability and cell division.
Show all 10 in In Vitro Assays
- In Vitro Efficacy Test Use in vitro models to test the efficacy of your products.
- Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
- Phenotype Assays Measure effects of drug candidate on the morphology or function of cells and whole animals.
- Stem Cell Differentiation Microscopy Assay› Elucidate mechanisms of stem cell renewal and differentiation in vitro using fluorescence microscopy.
In Vitro Pharmacology
- In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
- In Vitro Excitotoxicity Models Use in vitro models to measure therapeutic endpoints associated with excitotoxic pathology.
- In Vitro Hepatotoxicity Assays Use in vitro assays to measure hepatoxicity-related activities.
- In Vitro Neural Models Use cultured neurons, neuronal progenitor cells and stem cell differentiation to create cellular models of neurological disease.
- Target Identification Identify the target(s) of a biologically active substance.
In Vitro Toxicology
- Cardiomyocyte Toxicity Assess cytotoxic effects of pre-clinical compounds on cardiomyocytes.
- Cardiotoxicity Evaluate the effect of a compound on heart electrophysiology and muscle function.
- Cardiovascular Toxicology Measure the toxic effects of pre-clinical compounds.
- Cytotoxicity Test for effects on cell viability and proliferation
- Endothelial Cell Toxicity Assess the cytotoxic effects of pre-clinical compounds on the vascular system.
- hERG Inhibition Measure the arrhythmia-producing potential of test compounds.
Show all 7 in In Vitro Toxicology
- Perfused Heart Examine cardiac contractile strength (inotropic effects), heart rate (chronotropic effects) and vascular effects.
In Vivo Pharmacokinetics
- In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
Lab Supplies, Facilities, and Equipment
- Biobanking Store and track biological samples.
Management Optimization & Development Strategies
- Big Data Computational assistance with analysis of large data sets to reveal patterns, trends and associations
Model Development
- Fresh Functional Human Tissue Contractile Force Assays Use fresh functional human tissue to assess contractile force with various compounds.
- Fresh Functional Human Tissue Efficacy Assays Use fresh functional human tissue to assess pre-clinical efficacy of test compounds.
- Fresh Functional Human Tissue Ion Channel Activity Assays Use fresh functional human tissue to assess ion channel activity with various compounds.
- Fresh Functional Human Tissue Muscle Contraction Assays Use fresh functional human tissue to assess muscle contraction with various compounds.
- Fresh Functional Human Tissue Muscle Relaxation Assays Use fresh functional human tissue to assess muscle relaxation with various compounds.
- Fresh Functional Human Tissue Permeability Assays Use fresh functional human tissue to assess tissue permeability with various compounds.
Show all 11 in Model Development
- Fresh Functional Human Tissue Safety Assays Use fresh functional human tissue to assess pre-clinical safety of test compounds.
- Fresh Functional Human Tissue Vascular Permeability Assays Use fresh functional human tissue to assess vascular permeability with various compounds.
- Fresh Functional Human Tissue Vasoconstriction Assays Use fresh functional human tissue to assess vasoconstriction with various compounds.
- Fresh Functional Human Tissue Vasodilation Assays Use fresh functional human tissue to assess vasodilation with various compounds.
- Human Precision-Cut Lung Slice Model Acquire a fresh phenotypically-accurate model to study human lung behavior.
Safety Pharmacology
- Immunotoxicity Measure effects of drugs on immune function, allergic hypersensitization and autoimmune toxicity.
- Safety Pharmacology Assess the impact of a therapeutic for human use on vital organ systems before first-in-man drug testing.
Scientific Data Services
- Machine Learning/ AI Predict and model an outcome (e.g. disease progression) based on input variables (i.e. features.)
Testing Services
- In Vitro Skin Models Measure skin model penetration and invasion, photosensitivity and toxicity.
Other services
- New Request
Service areas:
Biology
Where it operates
Sites by country, with the cities in each.
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United Kingdom 2 sites
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United States 2 sites
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Japan 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Reprocell offers iPS, cardiomyocytes, rat cells, cell sorting, HLA services, and sample analysis. ReproCELL’s strength lies not only in its technologies for maintaining ES/iPS cells, but also in its ability to generate functional human cells out of ES/iPS cells. Efficient methods to derive functional cardiomyocytes, neurons and hepatocytes have been developed through national projects spearheaded by ReproCELL and Professor Nakatsuji, and other collaborators. These world class cutting-edge stem cell technologies have been licensed to ReproCELL for further development as our own proprietary...
Show the full description
Reprocell offers iPS, cardiomyocytes, rat cells, cell sorting, HLA services, and sample analysis. ReproCELL’s strength lies not only in its technologies for maintaining ES/iPS cells, but also in its ability to generate functional human cells out of ES/iPS cells. Efficient methods to derive functional cardiomyocytes, neurons and hepatocytes have been developed through national projects spearheaded by ReproCELL and Professor Nakatsuji, and other collaborators. These world class cutting-edge stem cell technologies have been licensed to ReproCELL for further development as our own proprietary technologies. Thanks to these world class collaborations, ReproCELL can supply the best quality human functional cells in large amounts to support those who seek to improve human health throughout the world.
- Website
- www.reprocell.com
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