Excellerate Bioscience

Excellerate Bioscience is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country.

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Sites 2

Countries 1

Type of company: Small business

Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
Immunophenotyping Separate cell types based on their expression of biomarkers or based on their individual and unique expression patterns.

Cell Sorting The purpose of cell separation is to isolate a cell population from other cells in a biological sample.
Signaling Pathways Find proteins, assays and custom reagents for the analysis of cell signaling pathways.

Blood Models Test for therapeutic efficacy of drug candidates in blood disorder models.
Comparative Pharmacology Compare drug responses across species for improved reliability in translational studies.

Plasmid DNA Preparation and Extraction Prepare plasmid DNA starting from E. coli cell pellets, transformed colonies or DNA samples.
qPCR Analysis Measure the accumulation of PCR products in real time.

Pharmacology Consulting Request consulting services related to pharmacology and the chemical properties, biological effects, and therapeutic uses of drugs.

Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
Apoptotic Cell Staining Detect apoptotic cells in culture.
Assay Development Construct or create new assays or modify existing ones.
BrdU S-Phase Analysis Assess cell division or apoptosis by measuring thymidine-analog label incorporation during DNA replication.
Caspase Assay Detect early to mid stage apoptosis or differentiate apoptosis from necrosis.
Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression

Show all 16 in In Vitro Assays 10 more

Cell Cycle Assays Measure cell cycle markers and the molecular events that control cell cycle progression.
Cell Proliferation Measure cell number, cell viability and cell division.
Cell-based Screening Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
Fully Automated Assays Develop and perform assays that require no manual steps
High Content Screening Analyze whole cells or components of cells with simultaneous readout of several parameters.
HTS Assay Development Develop assays to use in high throughput screening.
In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
Oxidative Burst Examine the release of reactive oxygen species (ROS) from neutrophils and other immune cells.
Phenotype Assays Measure effects of drug candidate on the morphology or function of cells and whole animals.

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Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
G-Protein Coupled Receptor (GPCR) Assays Detect ligand binding, receptor dimerization and downstream signal transduction events.
High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
Immuno-oncology Assays Use biochemical, cell based or in vivo assays to measure the activity of immuno-therapy targets.
In Vitro Bone Models Measure osteoclast activity and bone formation in human or rat osteoclasts.
In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.

Show all 17 in In Vitro Pharmacology 11 more

In Vitro Enzyme Activity Assay Development Develop new in vitro enzyme activity assays or modify existing ones.
In Vitro Hypoxia Models Use in vitro models to measure therapeutic endpoints associated with hypoxia.
Kinase Assays Measure activity of over 500 kinases in biochemical or cell-based assays.
Protease Assay Measure protease activity in biochemical and cell-based assays.
Protein/Enzyme Targets For requesting Protein/Enzyme Targets
Reversibility Study Determine whether or not a compound inhibits an enzyme reversibly.
Selectivity Profiling Determine the specificity of a ligand for its target by testing it against a large panel of related target proteins.
Substrate Competitive Study Determine whether or not a compound is competitive with a substrate.
Target Identification Identify the target(s) of a biologically active substance.
Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.
Time Dependent Study Determine whether or not a compound binds to an enzyme in a time-dependent manner.

Enzymology Enzymology studies the biochemical activity, structure, and function of enzymes. Two key area of Enzymology are Cytochrome P450...
Western Blots Detect specific proteins in a sample of tissue homogenate or extract.

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