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Research supplier
Asymchem Laboratories
Asymchem Laboratories is listed as a large business research supplier in the Scientist.com network, with 10 sites in 3 countries and 2 service areas.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Large business
Antibodies
- Antibody Conjugation Conjugate an enzyme, biotin, or fluorophore to an antibody.
- Antibody Purification Purify multiple antibody types including IgG, IgM, IgA and IgY.
- Antibody-Drug Conjugation Improve therapeutic properties of an antibody or drug by joining them together.
- Biotin-Antibody Conjugation Biotinylate an antibody for improved detection.
- Epitope Mapping Map the antibody-antigen binding region to define protein-protein interaction sites.
- In Vitro Monoclonal Antibody Production Generate monoclonal antibodies in vitro using cultured antibody-secreting hybridoma cell lines.
Show all 10 in Antibodies
- Monoclonal/Polyclonal Antibody Development Develop a monoclonal and/or polyclonal antibody.
- Rabbit Monoclonal Antibody Development Develop monoclonal antibodies using rabbit as the host animal.
- Recombinant Antibody Production Request services related to antibody production services.
- Single Chain Variable Fragment (scFv) Create an antigen-specific antibody derivative using a linker to join a heavy and a light variable chain.
Chemical and Compound Analysis
- API Physical Characteristics Characterize physical and chemical properties of new drug molecules to develop safe, effective, and stable dosage forms.
- Chemical Stability Measure the stability of small molecules in solution.
- Dissolution Profiling Measure release of API from formulation (tablet or capsules) under GMP guidelines.
- NMR Structure Determine molecular structure, identify chemical impurities and validate sample integrity.
- Optical Rotation Distinguish between optical isomers as well as between natural versus man-made compounds.
- Photostability Measure drug degradation rates after exposure to various light sources.
Show all 7 in Chemical and Compound Analysis
- Spray Drying Convert a liquid into a powder by rapidly drying the mixture and removing the moisture component.
Show all 45 services
Chemistry, Manufacturing and Controls (CMC)
- API Stress Testing Studies Develop analytical methods to predict stability problems and identify degradation products/pathways under forced degradation conditions.
- API/ Excipients Compatibility Studies Delineate real and possible interactions between potential formulation excipients and the API as an important risk reduction exercise early in formulation development.
- Bi-specific Antibodies Create a protein made of fragments of two monoclonal antibodies that bind to different antigens.
- Bulk Manufacturing Find facilities for large-scale mass production.
- Chemistry Manufacturing Controls Access contract manufacturing and regulatory guidance in setting specifications and drug dosage formulations.
- Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
Show all 17 in Chemistry, Manufacturing and Controls (CMC)
- Crystallization studies Crystallization studies
- Drug Formulation Combine substances including the active drug into a final product with the desired metabolic and therapeutic properties.
- Drug product packaging and labeling Drug product packaging and labelling
- Drug Product Stability Use accelerated stress conditions to determine degradation pathways and identify manufacturing issues.
- GMP Synthesis Synthesize APIs including small molecules, formulations and protein-based drugs under GMP compliance.
- ICH-compliant stability testing Perform ICH-compliant stability testing
- Milling, grinding, spray-drying Milling, grinding, spray-drying
- Polymorph Screening Screen for unwanted API forms resulting from the drug formulation process.
- Powder Blending Use automatic or semi-automatic powder blending machinery to produce consistent mixes.
- Salt Form Selection Use high-throughput automated arrays to combine APIs with multiple salts and ions to optimize formulation.
- Tablet Manufacturing Use automatic or semi-automatic machinery to create various standard and non-standard tablets.
Discovery Chemistry
- Compound Synthesis Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
DNA & RNA
- DNA Products Find DNA products including gDNA, cDNA clones, vectors and constructs from mice, insects, yeast, bacteria and viruses.
- mRNA synthesis Transcribe mRNAs in vitro and add modifications such as polyadenylation and guanine capping.
- Oligo Synthesis Produce oligonucleotides for microarrays, RT-PCR and PCR cloning.
- RNA oligo synthesis Design and synthesize miRNAs, siRNAs and other non coding RNAs
- siRNA Synthesis Produce high quality siRNAs for gene silencing studies.
In Vitro Toxicology
- ADCC and CDC Assay Services Measure toxicity of antibodies.
Protein Sciences
- Host Cell Protein Analysis Measure contamination of biologics with host proteins by using sequencing, chromatography and the LAL test.
- Recombinant Proteins Use recombinant DNA to produce proteins in vivo or in vitro.
- Solid Phase Peptide Synthesis Create peptides on solid supports with reduced product loss.
Other services
- New Request
Service areas:
Where it operates
Sites by country, with the cities in each.
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China 7 sites
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United States 2 sites
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United Kingdom 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Asymchem provides fully integrated services from early discovery to commercial manufacturing.
- Professional associations
- DCAT
- Website
- www.asymchem.com
Work with Asymchem Laboratories on Scientist.com
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