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Melior Discovery
Melior Discovery is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country and 1 service area.
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Sites
2
Countries
1
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Developmental and Reproductive Toxicology (DART)
- Bioelectronics Evaluate an application (e.g. device) that integrates biological materials and micro and nano-electronics.
Disease Models
- 5XFAD Mice for Alzheimer’s Disease (AD) The 5XFAD mouse is a popular transgenic Alzheimer's disease (AD) model that overexpresses mutant human APP and PSEN1 with five familial AD mutations
- Anxiety Models Measure therapeutic endpoints in animal models of anxiety.
- Atopic Dermatitis Models Measure therapeutic endpoints in animal models of atopic dermatitis.
- Behavioral Testing Models Investigate sensory-motor and emotional functions, social behavior and day-night activity.
- Cardiovascular Models Test the therapeutic efficacy of drug candidates in cardiovacular disease models.
- Cognition Models Measure therapeutic endpoints in animal models of cognition.
Show all 29 in Disease Models
- Dermatology Models Measure therapeutic endpoints in animal models of dermatological disorders.
- Electroencephalogram EEG Models Record electrical activity along the scalp of animal models or human patients.
- Electrophysiology Models Measure voltage change on a variety of scales from single ion channels to whole organs.
- fa/fa Zucker Diabetic Rats Use a single animal species to create one or more disease models for diabetes and obesity.
- General Pain Models Measure therapeutic endpoints in animal models of general pain.
- Hair Growth Models Measure dermal histology, skin thickness, % anagen induction, hair proliferation and other hair growth markers.
- Inflammation Models Measure therapeutic endpoints in animal models for inflammation.
- Inflammatory Bowel Disease Models Measure IBD symptom severity, cytokine levels and body weight, and evaluate IHC and Ariol images.
- Inflammatory Pain Models Measure therapeutic endpoints in animal models of inflammatory pain.
- Irritant Models Measure therapeutic endpoints in animal models of skin irritation.
- Liver Fibrosis Models Measure liver fibrosis using therapeutic endpoints such as collagen assessment, TUNEL staining and inflammatory markers.
- LPS Acute Response Models Measure therapeutic endpoints in acute models of inflammation.
- LPS Lung Inflammation Models Measure therapeutic endpoints in animal models of inflammation.
- Morris Water Maze Investigate spatial learning and memory in rodents.
- Neuroscience Models Test therapeutic efficacy of drug candidate in neurological disease model.
- Object Recognition Measure spatial navigation, working memory and cognitive function in animal models.
- Pain Models Test therapeutic efficacy of drug candidate in pain model.
- Parkinson's Disease Models Measure therapeutic endpoints in animal models of Parkinson's disease.
- Sclerosis ALS Models Measure therapeutic endpoints in animal models of sclerosis.
- Stroke Models Measure therapeutic endpoints in animal models of stroke.
- Systemic Lupus Erythematosus Models Measure therapeutic endpoints in animal models of immune disorders such as SLE and lupus.
- Thrombosis Models Measure therapeutic endpoints in animal models of thrombosis.
- Visceral Pain Models Measure therapeutic endpoints in animal models of visceral pain.
In Vitro Pharmacology
- High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
- Immuno-oncology Targets Develop drugs that take advantage of the immune system to target cancer cells.
- Target Characterization Characterize potential drug targets during the drug discovery process.
In Vivo ADME
- Absorption studies Study the factors determning how efficiently a compound may enter the bloodstream.
In Vivo Pharmacokinetics
- In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
- Pharmacokinetic (PK) Screening - Rat Run pharmacokinetic studies in rats that measure a drug's absorption, distribution, metabolism and excretion.
Show all 44 services
Model Development
- Surgical Models Create new animal models using techniques such as vascular catherization, soft tissue procedures or device implants.
- Zucker Rat Use a single animal species to create one or more disease models for cachexia.
Oncology Models
- Oncology Models Use model organisms to test the therapeutic efficacy of cancer drug candidates.
- Oncology Xenografts Xenografts derived from oncological samples.
Safety Pharmacology
- CNS Behavioral Measure safety toxicology effects of CNS and behavioral drugs.
- Safety Pharmacology Assess the impact of a therapeutic for human use on vital organ systems before first-in-man drug testing.
Testing Services
- Sebum Production Testing to evaluate the oil production in the skin
Other services
- New Request
Service areas:
Pharmacology
Where it operates
Sites by country, with the cities in each.
-
United States 2 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Melior Discovery offers in vivo pharmacology services, including in vivo efficacy models, PK studies, indications discovery and bioanalytical services. Specialty services include neurophysiology studies such as EEG, evoked potentials, sleep-wake models and analysis and nerve conduction assays.
- Professional associations
- American Association for Laboratory Animal Science (AALAS)
- Website
- www.meliordiscovery.com
Work with Melior Discovery on Scientist.com
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