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Neopharm

Neopharm is listed as a mid sized business research supplier in the Scientist.com network, with 1 site in 1 country and 1 service area.

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Sites 1

Countries 1

Type of company: Mid sized business

Chemical and Compound Analysis

Adsorption/Desorption Studies Obtain data on groundwater risk assessment.
Analytical Separations and Purification Analytical Separation and Purification of compound/molecule.
API Physical Characteristics Characterize physical and chemical properties of new drug molecules to develop safe, effective, and stable dosage forms.
Atomic Absorption Analysis Measure the elemental composition of a diverse array of samples.
Chemical Stability Measure the stability of small molecules in solution.
Chiral Separation Purify therapeutically active isomers of drug candidates.

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Compound Integrity Analyze the identity and purity of small molecule drug candidates.
Differential Scanning Calorimetry Elucidate the thermodynamics associated with conformational transitions.
Dissolution Profiling Measure release of API from formulation (tablet or capsules) under GMP guidelines.
Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
Elemental Impurity Analysis Identify and evaluate the presence of heavy metals in pharmaceuticals.
Endotoxin Testing Use standard assays like LAL (Limulus Amebocyte Lysate), rFC (Recombinant Factor C), or MAT (Monocyte Activation Test) to detect and quantify the level of endotoxins in a sample
Excipient Compatibility Test excipients for drug formulation, effects of temperature, time, humidity, pH and light exposure as well as excipient release.
Filler Content Analysis Evaluate filler material to optimize product performance and process conditions.
Gas Chromatography Gas chromatography is an analytical technique that separates, identifies, and quantifies compounds in a mixture
Headspace Gas Chromatography Analyze volatile organic compounds (VOCs) partitioned above the liquid/solid phase of a sample.
Heavy Metals Analysis Ensure trace levels of heavy metals are below the maximum allowable limits for consumer safety.
High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
Impurities in API Risk assessment Create a risk-based control strategy to determine any impurities in Active Pharmaceutical Ingredients (API).
Inductively Coupled Plasma (ICP) Analysis Characterize ultra-small levels of multiple solid analytes simultaneously.
Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) Analysis Detect metals and several non-metals at concentrations as low as one part in 1015 (part per quadrillion, ppq) on non-interfered low-background isotopes.
Ion Exchange Chromatography Separate and detect analytes.
Liquid Chromatography Separate substances using a mobile and stationary phase.
Melting Point Use melting point analysis to characterize compounds based on calorimetry and thermodynamic data.
NMR Methods Use nuclear magnetic resonance spectroscopy to identify drug intermediates.
NMR Structure Determine molecular structure, identify chemical impurities and validate sample integrity.
Non GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Optical Rotation Distinguish between optical isomers as well as between natural versus man-made compounds.
Particle Size Analysis Measure particle size distribution and characterize particle size, porosity and composition.
Partition Coefficient Determine lipophilicity (hydrophobicity) of compounds by measuring log P.
Photostability Measure drug degradation rates after exposure to various light sources.
Physicochemical Analysis Physicochemical Analysis of material or preparation evaluating (e.g.) particle size, composition, or compound structure.
Process Residual Impurities Detection Measure trace levels of impurities.
Protein Separation and Detection Separate proteins based on properties such as solubility, adsorption or size differences.
Protein Structure Determine the three dimensional structure of a protein by NMR or x-ray crystallography.
Raman Spectroscopy Use spectroscopic technique to observe vibrational, rotational and other low-frequency modes in a system.
Sample Bioanalysis Determination of concentration of an analyte in biological sample.
Size Exclusion Chromatography Separate and identify analytes based on their molecular size.
Solubility Studies Analyze substances for kinetics of solubility using nephelometry and UV-Vis spectrometry.
Structural Chemistry Examine the relationship between protein structure and function.
Structural Elucidation Determine chemical structure of a compound. Characterization techniques include mass spectrometry, infrared spectroscopy and X-ray crystallography.
Viscosity Testing Evaluate the fluid flow properties of liquids for product evaluation and quality control.

Chemical and Compound Testing

Bacterial Water Analysis Analyzing water samples to identify the bacteria present.
Limulus Amebocyte Lysate (LAL) Test Detect bacterial endotoxins in raw materials used for the production of cosmetics products.
Nutritional Testing Analyze food safety, vendor specifications, foreign substance identification processes and nutritional labeling.
Product Testing Ensure product quality standards are met.
USP <2021> Microbial Enumeration Tests Estimate the total aerobic microbial count, total combined yeast and mold counts, and the presence of bile-tolerant gram-negative bacteria present in nutritional supplements.
USP <2022> Microbiological Procedures for Absence of Specified Microorganisms Determine the absence of objectionable organisms in nutritional supplements.

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USP <85> Bacterial Endotoxin Test Test to detect or quantify bacterial endotoxins that may be present in or on a sample.

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Chemistry, Manufacturing and Controls (CMC)

Analytical Development and Validation Request services related to Analytical Development and Validation
API and Drug Product Stability Testing API and Drug Product Stability Testing.
API and drug product storage and release API and drug product storage and release
API Stress Testing Studies Develop analytical methods to predict stability problems and identify degradation products/pathways under forced degradation conditions.
API/ Excipients Compatibility Studies Delineate real and possible interactions between potential formulation excipients and the API as an important risk reduction exercise early in formulation development.
API/DP specific test methods API/DP specific test methods (e.g., stability indicating HPLC assay and purity)

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Chemistry Manufacturing Controls Access contract manufacturing and regulatory guidance in setting specifications and drug dosage formulations.
Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
Compendial test methods Run Compendial test methods (e.g., KF)
Drug Product Stability Use accelerated stress conditions to determine degradation pathways and identify manufacturing issues.
Drug Substance and Drug Product Characterization and Manufacturing Drug Substance and Drug Product Characterization and Manufacturing.
Forced Degradation Run light, heat, humidity, acid hydrolysis and oxidation tests to evaluate substance degradation.
ICH-compliant stability testing Perform ICH-compliant stability testing
Impurities in Drugs Risk Assessment Create a risk-based control strategy to determine any toxic elemental impurities that may be present in human medicines.
Raw Materials & Ingredients Purchase raw materials, ingredients, or chemicals for personal care, cosmetic, consumer health, and beauty products and substances.
Salt Form Selection Use high-throughput automated arrays to combine APIs with multiple salts and ions to optimize formulation.

Discovery Chemistry

Chiral Synthesis Synthesize a compound by a method that favors formation of a specific enantiomer or diastereomer.
Extractable and Leachable Assessment Quantify potential impurities from container closures & packaging.
Impurity Synthesis Use high resolution MS or NMR to eliminate intermediates or organic byproducts and determine impurity content.
Large Scale Purification Purify gram to kilogram amounts of recombinantly-expressed or wild-type proteins.
LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
Leachable and extractable testing Leachable and extractable testing

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Method Development and Validation Develop and validate methods for synthesis and scale up of drug candidates.
Polyethylene Glycols (PEGS) Acquire polyethylene glycols (PEGS) to use as ingredients in consumer healthcare products.
Trace Elemental Analysis Identify organic and inorganic elements in foods and dietary supplements at ppm to sub-ppt levels.
USP Testing Analytical Reagents Acquire chemical reagents, solution concentrates and volumetric solutions used to evaluate items in USP testing.
UV and IR Profiling Analyze the integrity of a compound or large biomolecule.
Virtual Screening Use software algorithms to virtually screen millions of potential compounds and peptides for binding.

In Vitro Assays

Assay Development Construct or create new assays or modify existing ones.
Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
Pathogen Assays Detect and distinguish viral, bacteria and fungal strains and species.

In Vitro Toxicology

Cytotoxicity Testing Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.

Medical Communications

Protocol and Study Reports Write protocol and study reports, specifically relating to the drafting, writing, and editing of Clinical Safety Reports.

Other Specialty Toxicology

Microbial Testing Test samples for microorganisms, identify species, do bioburden analysis and measure endotoxin levels (LAL).
United States Pharmacopeia (USP) Testing Use USP standards to ensure quality of pharmaceuticals, supplements and food ingredients.

Protein Sciences

ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
Peptide Mapping Confirm the identity, purity, and primary structure of proteins, particularly monoclonal antibodies
Protein Identification Uncover or confirm the identity of a protein.
Protein Post-translational Modification Analysis Measure glycosylation, phosphorylation, sulfation, ubiquitination, methylation and acetylation.

Testing Services

Accelerated Stability Determine shelf life of drug formulations by comparing API breakdown at elevated temperature.
Characteristic Testing Characterization of physical and chemical properties of raw materials
Elevated Temperature Stability Determine the stability of a product at elevated temperature.
Freeze-Thaw Testing Use freeze-thaw cycling to measure the long-term durability of cosumer products.
Microbiological Sterility Testing Test the presence of viable microorganisms.
Package Compatibility Tests Ensure that the consumer product is not adversely affected by the package components and vice versa.

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Raw Material Microbiological Testing Examples of which include Microbial Content using USP <61> and <62> and other standards, LAL Endotoxin, Ames Mutagenicity and Sterility.
Real-time Stability Test Assure stability and physical integrity of consumer products in real-time conditions.
USP 51 Cosmetic Preservative Efficacy Test Evaluate the antimicrobial stabilization of a cosmetic product as per USP 51.
USP <61> Microbial Limits Test Determine whether a substance or preparation complies with an established specification for microbiological quality.
USP <62> Microbial Limits Test Determine the presence or absence of specific microorganisms.

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Chemistry

Canada Blainville 1 site

Working with Averica, chemistry teams and program managers make the best decisions possible, as quickly as possible. Averica is a contract research organization (CRO) with specialized expertise in small molecule analysis and purification. We work with chemistry-driven discovery and development teams to speed drug candidate selection and shorten timelines into early development. Averica was founded in 2007 as a source of chromatography expertise, with a leadership team having extensive experience in pharmaceutical R&D. We began using Supercritical Fluid Chromatography (SFC) technology...

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Working with Averica, chemistry teams and program managers make the best decisions possible, as quickly as possible.

Averica is a contract research organization (CRO) with specialized expertise in small molecule analysis and purification. We work with chemistry-driven discovery and development teams to speed drug candidate selection and shorten timelines into early development.

Averica was founded in 2007 as a source of chromatography expertise, with a leadership team having extensive experience in pharmaceutical R&D. We began using Supercritical Fluid Chromatography (SFC) technology in chiral and achiral separations, and have expanded to become a supplier of a wide variety of chromatography and analytical services. These services include providing scalable supply of predevelopment candidates, isolation and identification of unknown impurities, and custom analytical work aimed at assessing the “developability” of compounds.

Averica is located in the heart of the East Coast pharma corridor, just west of Boston, Massachusetts. Our name comes from the verb aver, meaning verify or prove true. Through strengths in speed and problem solving, we help companies understand their compounds and build confidence in their strategies.

Professional associations: ACS, MassBio
Website: www.neopharmlabs.com

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