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Orla Protein Technologies
Orla Protein Technologies is listed as a new startup research supplier in the Scientist.com network, with 2 sites in 1 country and 1 service area.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: New startup
Antibodies
- Single Chain Variable Fragment (scFv) Create an antigen-specific antibody derivative using a linker to join a heavy and a light variable chain.
Cell Culture and Characterization
- Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
- Stem Cell Differentiation Acquire specialized cells from differentiated stem cells.
In Vitro Assays
- Assay Development Construct or create new assays or modify existing ones.
- Biosensor Assays Evaluate biological activity of new compounds, detect toxic metabolites or monitor biomarkers.
Product Orders
- Kits and Reagents Submit a request to multiple vendors for kits and reagents.
Protein Sciences
- Bacterial Expression Produce milligram, gram and kilogram amounts of proteins.
- ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
- Protein Binding Determine drug-protein binding interactions
- Protein Expression Produce recombinant proteins in prokaryotic or eukaryotic systems.
- Protein Products Find native and recombinant proteins and peptides.
- Protein Purification Isolate native or recombinant proteins from a sample.
Service areas:
Where it operates
Sites by country, with the cities in each.
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United Kingdom 2 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Orla technology allows the immobilisation of proteins to surfaces in a highly ordered and functional manner. The protein of interest is fused to a proprietary surface-binding protein to produce a fusion protein. This can bind to surfaces anchored via the surface binding protein leaving the protein of interest distal to the surface, structurally intact and with high retention of function. This technology is offered for use in a variety of applications: 1. Protein immobilization for biosensor chip functionalization. Immobilization of antigens, small epitopes, and single-chain antibody...
Show the full description
Orla technology allows the immobilisation of proteins to surfaces in a highly ordered and functional manner. The protein of interest is fused to a proprietary surface-binding protein to produce a fusion protein. This can bind to surfaces anchored via the surface binding protein leaving the protein of interest distal to the surface, structurally intact and with high retention of function.
This technology is offered for use in a variety of applications:
1. Protein immobilization for biosensor chip functionalization. Immobilization of antigens, small epitopes, and single-chain antibody fragments as capture surfaces. Proven to have higher surface exposure compared to adsorption or chemical coupling.
2. Protein immobilisation on ELISA plate surfaces. Immobilization of antigens, small epitopes, and single-chain antibody fragments as capture surfaces. Proven to have higher surface exposure compared to adsorption or chemical coupling.
3. Coated plates for cell culture. Surfaces coated with ECM proteins and/or growth factors (see www.orlaproteins.com for a full list of available proteins). Highly reproducible. Try our OrlaExplorerTM plates to discover the optimal growth surface for your cell/media combination. The coating is transferable across a range of formats – multi-well plates, flasks, 3D matrices, beads etc. Uniquely, we can mix and match different ECM motifs and growth factors on the same growth surface to closely mimic in vivo conditions.
4. Immobilisation of enzymes. The use of an anchor protein allows us to design and engineer the fusions in such a way as to control the position and orientation of the enzymatic domains and active sites, thereby retaining higher structural integrity compared to direct adsorption or chemical coupling.
In addition, we provide services for the contract manufacturing of recombinant proteins at the 1 mg-100 mg scale. Ideal for antigen production, pilot experiments etc. We express in E. coli either as soluble protein or, if necessary, as inclusion bodies and have a wealth of experience in the refolding of proteins from inclusion bodies.
- Website
- www.orlaproteins.com
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