IAS

IAS is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country and 2 service areas.

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Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 2

Countries 1

Type of company: Small business

API Physical Characteristics Characterize physical and chemical properties of new drug molecules to develop safe, effective, and stable dosage forms.
Chemical Stability Measure the stability of small molecules in solution.
Chiral Separation Purify therapeutically active isomers of drug candidates.
Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
Excipient Compatibility Test excipients for drug formulation, effects of temperature, time, humidity, pH and light exposure as well as excipient release.
GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.

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GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Ion Exchange Chromatography Separate and detect analytes.
Liquid Chromatography Separate substances using a mobile and stationary phase.
Non GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Protein Separation and Detection Separate proteins based on properties such as solubility, adsorption or size differences.
Sample Bioanalysis Determination of concentration of an analyte in biological sample.
Secondary Ion Mass Spectrometry Detect trace level impurities and obtain elemental or molecular chemical data for solid sample surfaces.
Size Exclusion Chromatography Separate and identify analytes based on their molecular size.
Solubility Studies Analyze substances for kinetics of solubility using nephelometry and UV-Vis spectrometry.
UV-Spectroscopy Conduct sample analysis based on light absorption and transmission.

Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services

LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.

Compound Distribution Determine the metabolic fate of a drug candidate in tissue and organs of diseased and normal animal models.
CYP Inhibition Assay Assess the inactivation and inhibition of cytochrome P450 (CYP450) in microsomes isolated from primary human hepatocytes or liver.
GI Fluid Stability Determine dosing and turnover of drug candidates in gastrointestinal fluids.
Metabolic Stability Measure metabolic vulnerability to drug metabolizing enzymes using cell-free, cell-based and in vivo assays.
Metabolic Stability in Hepatocytes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver cells.
Metabolic Stability in Microsomes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver microsomes.

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Metabolite Generation Analyze the formation of drug metabolites after administration of drug to an animal model or patient.
Metabolite Identification Identify drug metabolites that are formed after administration of drug to an animal model or patient.
Metabolite Quantification Quantify drug metabolites formed after drug administration to an animal model or patient.
Metabolite Structural Elucidation Use analytical tools to characterize metabolite structure.
Metabolite Synthesis Synthesize drug metabolites that are formed after administration of drug to an animal model or patient.
No Label Methods Use mass spectrometry to detect and identify non-radiolabeled drug intermediates in pre-clinical samples.
Plasma Stability Assay Determine degradation rate of drug candidates in plasma.
Red Blood Cell (RBC) Partitioning (Blood/Plasma Ratio) Measure the distribution of a compound between red blood cells and plasma.

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Service areas:

Biology DMPK

Integrated Analytical Solutions (IAS) provides bioanalytical, metabolism, and LC/MS services.

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