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esqlabs GmbH
esqlabs GmbH is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country.
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Sites
1
Countries
1
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Biomarkers
- Anatomic Pathology Do macroscopic, microscopic, biochemical, immunologic and molecular examination of organs and tissues.
Clinical Trials
- Clinical Trial Design Develop study-related protocols, case report forms (CRFs) and database tools for records management.
- Pharmacokinetic Studies Design a study that observes the time course of drug absorption, distribution, metabolism, and excretion, as means to test the safety and effective therapeutic management of drugs in an individual patient.
Data Science/Bioinformatics
- Biostatistical Design Use statistics to ensure appropriate pre-clinical and clinical study design.
- Discovery In Silico Drug Dynamics Develop In Silico model of a drug candidate with a biological system with applications such as Pro-drug Predictions, ADME-PK Due Diligence, Brain-Barrier Permeability Simulation, Drug Absorption Simulation, In Silico...
- Discovery Statistical and Mathematical Modeling Use mathematical variables and equations to establish relationships between data.
- In Silico ADME-PK Consultation Consult with experts for ADME-PK data analysis or predictive modelling design in different in vivo or in vitro states.
- In Silico ADME-PK Predictions Use computer software to simulate in vivo physiological conditions of animals or humans to predict ADME-PK properties.
- In Silico Drug-Drug Interactions Use computational tools to predict pharmaceutical, pharmacodynamic or pharmacokinetic drug-drug interactions to maximize drug regimen safety.
Show all 8 in Data Science/Bioinformatics
- In Silico Pro-drug Predictions Use computer simulation to assess pro-drug absorption and conversion to predict pharmacokinetic properties.
- Translational Software tools Software designed to serve the needs of translational research groups.
Discovery Chemistry
- In Silico Lead Optimization Use in silico design to enhance the ADME-PK properties of candidate drugs to maximize efficacy and safety.
- In Silico Metabolite Predictions Conduct in silico assessment of metabolite pharmacokinetic properties and potential exposure effects.
Disease Models
- Cardiovascular Models Test the therapeutic efficacy of drug candidates in cardiovacular disease models.
- Chronic Kidney Disease Models Measure therapeutic endpoints in animal models of chronic kidney disease.
- Critical Care Models Diagnose and manage life-threatening conditions requiring sophisticated organ support and invasive monitoring.
- Dermatology Models Measure therapeutic endpoints in animal models of dermatological disorders.
- Disease Simulation Modeling Disease Simulation Modeling
- Respiratory Models Test therapeutic efficacy of drug candidate in respiratory disease model.
Show all 43 services
Drug Development
- Small Molecule Drug Development Consulting Request consulting services related to small molecule development.
Effectiveness
- Bioequivalence Studies for Veterinary Drugs Assess the expected biological equivalence of two proprietary preparations of a veterinary drug.
In Vitro ADME
- Drug Drug Interactions Determine whether a substance affects the activity of a drug when both are administered together.
- Radiolabeled Tracers Use radiolabeled drug metabolites as radiotracers for measuring desired physiological processes.
- Skin Permeability Use human skin models to determine transdermal delivery and percutaneous absorption of pre-clinical drugs.
In Vivo ADME
- Absorption studies Study the factors determning how efficiently a compound may enter the bloodstream.
- Milk Secretion Study - Other Species Conduct a study to determine the extent of milk secretion of your radioactive compound in other species.
In Vivo Pharmacokinetics
- In Vivo PK Consulting Expert advice on pharmacokinetics and how specific drugs affect the body to determine function, effectiveness, dosage size, etc…
- Maximum Tolerated Dose (MTD) Studies Determine Maximum Tolerated Dose (MTD) of a drug candidate in either a single or repetitive dosing study in a rodent (typically mouse or rat).
- Repetitive Maximum Tolerated Dose (MTD) Rat Study Use rat models to determine the MTD of a drug candidate by repetitive administrations for 7 days.
Model Development
- Custom Model Development Develop a custom disease model.
- In Silico PK-PD Modeling Quantitative modeling and simulations correlation of pharmacokinetic and pharmacodynamic endpoints in support of preclinical and clinical development.
Oncology Models
- Oncology Models Use model organisms to test the therapeutic efficacy of cancer drug candidates.
Regulatory Consulting
- Toxicology Data Review Identify relevant toxicological endpoints for “No Observed (Adverse) Effect Level” (NO(A)EL) or “Lowest Observed (Adverse) Effect Level” (LO(A)EL).
Safety Pharmacology
- Safety Pharmacology Assess the impact of a therapeutic for human use on vital organ systems before first-in-man drug testing.
Scientific Data Services
- Bayesian Statistics Extract information from data sets that are subject to error or noise to see unobserved possibilities.
- Bioinformatics Bioinformatics is a powerful method of storing, retrieving and analyzing biological data.
- Cancer Systems Biology Convert complex molecular data obtained from high-throughput technologies to deducible information.
- Discovery Computational Systems Biology Model the interaction of biological system with drug candidates.
- Machine Learning/ AI Predict and model an outcome (e.g. disease progression) based on input variables (i.e. features.)
- Systems Biomedicine Analyze complex interactions in biological systems with interdisciplinary scientific teams.
Show all 8 in Scientific Data Services
- Systems Network Analysis Analyze and visualize molecular pathways including gene regulatory, protein-protein and drug-target networks.
- Systems Pharmacology Understand how drugs interact with different molecular and cellular systems within biological models.
Target Animal and Human Food Safety
- Toxicokinetic Analysis Determine the drug concentration at which off-target or toxic effects occur.
Where it operates
Sites by country, with the cities in each.
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Germany 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
esqlabs GmbH is a vedor providing pharmacometrics consuliting & solutions using innovative physiologically-based quantitative systems pharmacology methods to predict preclinical and human population kinetics and/or dynamics.
- Website
- www.esqlabs.com
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