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Vanderbilt University Medical Center
Vanderbilt University Medical Center is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country.
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Sites
1
Countries
1
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Agricultural Sciences Research & Development
- Method Development & Validation Engineer sensitive and selective methods that meet GLP validation requirements to access different agrochemical properties
Bioimaging
- Confocal/Optical Microscopy Use optical imaging technique to increase optical resolution and contrast of a micrograph.
- Microscopy Use microscopy to analyze surfaces of biological materials and to develop 3D images of biological structures.
Biomarkers
- Cell Migration Assays Measure chemotaxis, haptotaxis, transmigration and wound-healing.
- Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
- Fluorescent In Situ Hybridization Use FISH to identify abnormal chromosome structures and to quantify specific DNA sequences.
- Histopathology Evaluate slide preparation of cells or tissues for abnormal features.
- Human Primary Cell Isolation Isolate primary cells from various human tissues.
- Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
Show all 8 in Biomarkers
- Immunohistochemistry Examine the toxic effects of pre-clinical compounds in small animal and patient histological samples.
- Wound Healing Assay Use cell-based assays to investigate cell proliferation, cell migration and wound closure.
Cell Culture and Characterization
- Cell Culture Culture primary or immortalized cell lines.
- Explant Culture Culture cells obtained from a part or parts of an in vivo structure.
- Histology Examine by microscopy the anatomy of cells and tissues of clinical patients and animal models.
Show all 68 services
Discovery Chemistry
- Method Development and Validation Develop and validate methods for synthesis and scale up of drug candidates.
Disease Models
- Diabetic Retinopathy Models Assess therapeutic efficacy of drug candidates in diabetic retinopathy models of disease.
- In Vivo Physiologic Monitoring Monitor and collect data from conscious, freely moving laboratory animals.
- Inflammation Models Measure therapeutic endpoints in animal models for inflammation.
- Ischemia Models Measure therapeutic endpoints in animal models of ischemia.
- Macular Degeneration Models Use a single animal species to create one or more models for eye disease.
- Ocular Inflammation Models Measure ocular inflammation in models of eye disorders such as uveitis and keratitis.
Show all 7 in Disease Models
- Ophthalmic Models Test drug candidates in glaucoma, macular degeneration, keratitis, uveitis and CMV retinitis models.
DNA & RNA
- qPCR Analysis Measure the accumulation of PCR products in real time.
- Quantitative RT PCR Use quantitative reverse transcription polymerase chain reaction to measure absolute and relative mRNA abundance.
- RNA Sequencing Use Next Generation Sequencing techniques to Identify RNA transcripts, examine differential expression patterns and analyze splice variants.
Drug Development
- Target Validation Consulting Help to demonstrate that modification of target activity has potential therapeutic benefits.
General in vivo Toxicology
- Dose Range Finding Study - Mouse Conduct a study to determine the dose range of your compound in mice.
- Dose Range Finding Study - Rat Conduct a study to determine the dose range of your compound in rats.
- General Toxicology Use in vivo models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.
- Repeat Dose Toxicity Study - Mouse Conduct a repeat dose study in mice to determine the toxicity and toxicokinetic behavior of your compound.
- Repeat Dose Toxicity Study - Rat Conduct a repeat dose study in rats to determine the toxicity and toxicokinetic behavior of your compound.
- Single Dose Acute Toxicity Study - Mouse Conduct a single dose study in Mice and Murines to determine the toxicokinetic behavior of your compound.
Human Biological Samples
- Human Primary Cells Acquire fresh/frozen human primary cells based on patient demographics, disease stage, history and treatment. Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely”...
In Vitro Assays
- Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Cell Based Assays Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
- Cell Proliferation Measure cell number, cell viability and cell division.
- In Vitro Efficacy Test Use in vitro models to test the efficacy of your products.
- Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
Show all 7 in In Vitro Assays
- Tube Formation Assay Monitor the in vitro formation of three dimensional 3D tube structures.
In Vitro Pharmacology
- In Vitro Eye Models Measure cytokine production, cell viability, apoptosis and wound healing.
- In Vitro Hypoxia Models Use in vitro models to measure therapeutic endpoints associated with hypoxia.
- Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.
- Vascular Endothelial Growth Factor (VEGF) Assays Use biochemical, cell based or in vivo assays to monitor competitive or non-competitive binding of VEGF ligand.
- Vascular Endothelial Growth Factor Receptor (VEGFR) Assays Use biochemical, cell based or in vivo assays to measure VEGF receptor activity.
In Vitro Toxicology
- Cytotoxicity Test for effects on cell viability and proliferation
- Endothelial Cell Toxicity Assess the cytotoxic effects of pre-clinical compounds on the vascular system.
In Vivo ADME
- Ocular Distribution Study - Rabbit Conduct a study to determine the distribution of your compound in ocular tissues of the rabbit.
- Ocular Distribution Study - Rat Conduct a study to determine the distribution of your compound in ocular tissues of the rat.
In Vivo Pharmacokinetics
- In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
- In Vivo PK Consulting Expert advice on pharmacokinetics and how specific drugs affect the body to determine function, effectiveness, dosage size, etc…
- Ocular Pharmacokinetic (PK) Screening - Rabbit Conduct a pharmacokinetic screening study in rabbits that measures the absorption, distribution, metabolism and excretion of your compound following ocular administration.
- Ocular Pharmacokinetic (PK) Screening - Rat Conduct a pharmacokinetic screening study in rats that measures the absorption, distribution, metabolism and excretion of your compound following ocular administration.
- Pharmacokinetic (PK) Screening - Mouse Run pharmacokinetic studies in mice that measure a drug's absorption, distribution, metabolism and excretion.
- Pharmacokinetic (PK) Screening - Rat Run pharmacokinetic studies in rats that measure a drug's absorption, distribution, metabolism and excretion.
Non-Human Biospecimen
- Mouse Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
- Mouse Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
- Mouse Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.
- Rat Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
- Rat Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
- Rat Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.
Oncology Models
- Angiogenesis Models Measure therapeutic endpoints in animal models of angiogenesis.
- Animal Hypoxia Models Measure therapeutic endpoints in hypoxic animal models.
Protein Sciences
- Cytokines Find recombinant cytokines or cytokine assays.
- ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
- Western Blots Detect specific proteins in a sample of tissue homogenate or extract.
Specialty Dosing Routes
- Ophthalmologic Toxicology Measure toxicity by microscopy, vitrectomy, tonometry, electroretionography and corneal colorimetry.
Other services
- New Request
- Website
- vo-cro.com
Where it operates
Sites by country, with the cities in each.
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United States 1 site
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