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Research supplier
Shanghai Lide Biotech
Shanghai Lide Biotech is listed as a mid sized business research supplier in the Scientist.com network, with 3 sites in 1 country.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Mid sized business
Biomarkers
- Biomarker Discovery Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.
- Pharmacodynamic Biomarkers Discovery Identify candidate biomarkers indicative of the therapeutic outcome of a drug-target interaction.
- Predictive Biomarkers Discovery Identify candidate biomarkers suggestive of a response to a treatment.
- Solid Tumor CDx Design and validate companion diagnostics for solid tumors that help select the most appropriate patients, identify patients at increased risk, or monitor treatment effectiveness.
Cell Culture and Characterization
- 3D Cell Culture Use a scaffold-based or scaffold-free format to grow three dimensional cell and tissue structures.
- Cell Culture Culture primary or immortalized cell lines.
- Human Melanoma Cell Lines Obtain highly characterized cell lines derived from patients’ tumors for in vitro and in vivo modelling.
- In Vitro Hydrogel-Based Culture of PDXs Enable the extended laboratory culture of cancer PDXs and other primary cells in 3D.
Clinical Trials
- Pharmacokinetic Studies Design a study that observes the time course of drug absorption, distribution, metabolism, and excretion, as means to test the safety and effective therapeutic management of drugs in an individual patient.
Companion Diagnostics
- Cervical Cancer CDx Design and validate companion diagnostics for cervical cancer that help select the most appropriate patients, identify patients at increased risk, or monitor treatment effectiveness.
- Pancreatic Cancer CDx Design and validate companion diagnostics for pancreatic cancer that help select the most appropriate patients, identify patients at increased risk, or monitor treatment effectiveness.
Discovery Chemistry
- Time of Flight Mass Cytometry (CyTOF™) Detect and quantify up to 34 different proteins simultaneously on a single-cell level.
Show all 54 services
Disease Models
- Blood Models Test for therapeutic efficacy of drug candidates in blood disorder models.
- In Vivo Technologies Models Carry out EEGs, cognition assessment, microdialysis, electrophysiology, MRI, ultrasound and tomographic analysis.
- Xenografts Evaluate drug candidate in tissue graft or organ transplant model.
DNA & RNA
- RNAi Pathway Analysis Use high-throughput RNAi genetic screens to elucidate relevant signaling pathways.
General in vivo Toxicology
- Single Maximum Tolerated Dose (MTD) Mouse Study Use mouse models to determine the MTD of a drug candidate by a single administration in a 7 day period.
Human Biological Samples
- Custom PDX models For requesting Custom PDX models
- Existing PDX models For requesting Existing PDX models
In Vitro ADME
- Drug Drug Interactions Determine whether a substance affects the activity of a drug when both are administered together.
In Vitro Assays
- In Vitro Efficacy Test Use in vitro models to test the efficacy of your products.
In Vitro Pharmacology
- Human Epidermal growth factor Receptor (HER) Assays Use biochemical, cell based or in vivo assays to measure HER receptor activity.
- Immuno-oncology Assays Use biochemical, cell based or in vivo assays to measure the activity of immuno-therapy targets.
- Immuno-oncology Targets Develop drugs that take advantage of the immune system to target cancer cells.
- In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
- In Vitro Oncology Models Use cell-based and biochemical models of cancer.
- Programmed Cell Death-1 (PD-1) Assays Use biochemical, cell based or in vivo assays to measure PD-1 receptor activity.
Show all 8 in In Vitro Pharmacology
- Target Identification Identify the target(s) of a biologically active substance.
- Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.
In Vivo Pharmacokinetics
- In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
- Repetitive Maximum Tolerated Dose (MTD) Mouse Study Use mouse models to determine the MTD of a drug candidate by repetitive administrations for 7 days.
Model Development
- Custom Model Development Develop a custom disease model.
- Disease Model Database For sourcing disease models.
- PBMC Humanized Mice Study and evaluate compounds for infectious diseases and graft rejection.
Oncology Models
- CAR-T Efficacy In Vivo assessment of CAR-T and CAR-NK efficacy in a humanized mouse
- Digestive System PDX Patient derived xenografts relating to organs and components of the digestive system. This includes, but is not limited to the Stomach, Intestines, Liver, Colon, Colorectal samples and Gastric samples.
- Endocrine System PDX Patient derived xenografts related to the endocrine system. PDX related to glands controlling hormone regulation such as the Pituitary glands, Thyroid Glands, Adrenals, and Pancreas.
- Endocrine System Xenograft Xenografts derived from organs and glands of the Endocrine system. This include samples from the Pituitary Gland, Thyroid, and Adrenals.
- Immuno-PDX Utilize the patient-derived xenograft for drug response profiling and biomarker discovery of immuno-oncology drug candidates.
- Leukemia PDX Measure therapeutic endpoints in patient-derived xenografts of leukemia.
Show all 17 in Oncology Models
- NCG Model Study tumor biology and immuno-oncology in the CRISPR/Cas9-generated immunodeficient mouse model.
- Nervous System PDX Patient derived xenografts relating to the components of the Nervous System. This includes PDX from the Brain, Spinal Cord, and Nerves.
- Nervous System Xenografts Xenografts relating to the Nervous system. This includes samples from the Head, Neck, Brain, and Nerves.
- Oncology Derived PDX Patient derived xenografts derived from various oncological samples. This includes, but is not limited to, samples from Lymphoma, Melanoma, and Leukemia.
- Oncology Models Use model organisms to test the therapeutic efficacy of cancer drug candidates.
- Oncology Xenografts Xenografts derived from oncological samples.
- Ovarian Cancer Mouse Measure therapeutic endpoints in animal models of ovarian cancer.
- Reproductive System PDX Patient derived xenografts relating to reproductive systems. This includes PDX from reproductive organs such as the Ovaries, Cervix, Breasts, Testes, Prostate, and Scrotum.
- Reproductive System Xenografts Xenografts relating and derived from the reproductive systems. This includes samples from the ovaries, cervix, vulva, uterus, testes, scrotum, and prostate.
- Urinary System PDX Patient Derived Xenografts relating to organs that comprise the Urinary system. This includes, but is not limited to, samples from the Kidneys, Liver, and Bladder.
- Xenograft Models Measure therapeutic endpoints in cancer models using tumor cells transplanted from a donor of a different species.
Other services
- Human Dendritic Cell (hDC) Model Test and validate the immune-modulating compounds in DC immune pathway models.
- In Vivo Hollow Fiber Assay Evaluate test items concurrently with three different tumor cell lines within the same mouse.
- New Request
Where it operates
Sites by country, with the cities in each.
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China 3 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
We are committed to engage in translational cancer research, transform laboratory research result to clinical therapy, help and guide clinical drug administration and offer personalized therapy for patients. We offer high quality project management and consultancy for tailored drug discovery and development. LIDE is well recognized by the scientific community and some of the top tire pharmaceutical companies and biotech companies use and appreciate our services. Today with state-of-the-art pharmaco- genomic technology, LIDE is also committed to the identification and validation of tests...
Show the full description
We are committed to engage in translational cancer research, transform laboratory research result to clinical therapy, help and guide clinical drug administration and offer personalized therapy for patients. We offer high quality project management and consultancy for tailored drug discovery and development. LIDE is well recognized by the scientific community and some of the top tire pharmaceutical companies and biotech companies use and appreciate our services. Today with state-of-the-art pharmaco- genomic technology, LIDE is also committed to the identification and validation of tests predicting patients response to anti-cancer agent (personalized medicine).
Lab for Innovated Diagnosis and Experimental Therapeutics (LIDE) is a company for translational medicine. Founded in 2011 by overseas returnees Drs. Danyi Wen, Yizhun Zhu and few others, LIDE specializes in Oncology Translational Research. With years of experience, LIDE has established a unique collection of more than hundred patient derived xenograft (PDX) models.
LIDE adopts the high international standard in daily operation. The company owns SPF level Animal Centers (to be AAALAC accredited), safety level 2 laboratories and world-class equipments. Company brings together first-class research and management teams, with solid scientific background and project management experience.
LIDE focuses on the frontier of international translational medical research, and vigorously promotes the development and application of translational medical research in China.
Our Susidiaries are : Xian Lide , Shanghai LIWEN
- Professional associations
- AAPS
- Website
- www.lidebiotech.com
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