- Supplier site
- Group of sites (click to zoom)
Scientist.com supplier network (site locations)
Research supplier
Signatope GmbH
Signatope GmbH is listed as a small business research supplier in the Scientist.com network, with 3 sites in 1 country.
Sign in to Scientist.com to open this supplier in your organization's marketplace.
Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Biomarkers
- Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
- Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
Chemical and Compound Analysis
- Immunoaffinity Chromatography Use antibody-antigen interactions to isolate and concentrate analytes.
- Ion Exchange Chromatography Separate and detect analytes.
- Liquid Chromatography Separate substances using a mobile and stationary phase.
- Protein Separation and Detection Separate proteins based on properties such as solubility, adsorption or size differences.
- Size Exclusion Chromatography Separate and identify analytes based on their molecular size.
Discovery Chemistry
- LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
Disease Models
- Drug-Induced Liver Injury (DILI) Toxicity Assays Use biochemical, cell-based or in vivo assays to measure toxicity from drug-induced liver injury.
General in vivo Toxicology
- Mammalian Toxicology Use toxicity testing models to carry out required FDA or REACH safety testing.
In Vitro ADME
- Cytochrome P450s Assess the inhibition or induction of the various isozymes of cytochrome P450s by drug candidates.
In Vitro Assays
- Assay Development Construct or create new assays or modify existing ones.
Show all 19 services
In Vitro Toxicology
- Hepatocyte Toxicity Assess the cytotoxic effects of pre-clinical compounds on hepatocytes purified from patients and animal models.
Protein Sciences
- ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
- LCMS/MS Analysis Liquid chromatography–mass spectrometry is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography with the mass analysis capabilities of mass spectrometry.
- Protein Purification Isolate native or recombinant proteins from a sample.
- Proteomics Do large-scale experimental analysis of proteins focused on understanding structure and function.
- Western Blots Detect specific proteins in a sample of tissue homogenate or extract.
Target Animal and Human Food Safety
- Toxicity Test for Veterinary Drugs Use the drug at 10X the recommended dose for 3X the recommended duration to evaluate its safety.
Where it operates
Sites by country, with the cities in each.
-
Germany 3 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
SIGNATOPE develops the next generation of protein biomarker assays using a novel type of mass spectrometry-based immunoassays. SIGNATOPE (SIGNAture epiTOPE) immunoassays are capable of detecting and quantifying protein biomarkers in humans and all pharmacologically relevant model species. Antibodies comprising epitopes of 4 amino acids are the key reagents of SIGNATOPE´s immunoassays. The short epitope allows us to establish quantitative assays for the same protein in different species and for isoforms of protein families. Even immunoassays for notoriously difficult proteins like drug...
Show the full description
SIGNATOPE develops the next generation of protein biomarker assays using a novel type of mass spectrometry-based immunoassays.
SIGNATOPE (SIGNAture epiTOPE) immunoassays are capable of detecting and quantifying protein biomarkers in humans and all pharmacologically relevant model species. Antibodies comprising epitopes of 4 amino acids are the key reagents of SIGNATOPE´s immunoassays. The short epitope allows us to establish quantitative assays for the same protein in different species and for isoforms of protein families. Even immunoassays for notoriously difficult proteins like drug transporters can be established while providing the speed and the sensitivity of an antibody-based method.
- Website
- signatope.com
Work with Signatope GmbH on Scientist.com
For prices, more details, or to contact Signatope GmbH, visit Scientist.com.
Sign in to Scientist.com to open this supplier in your organization's marketplace.