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Bio-Techne
Bio-Techne is listed as a large business research supplier in the Scientist.com network, with 4 sites in 2 countries.
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Sites
4
Countries
2
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Large business
Antibodies
- Antibody based Assay Development Create specific and sensitive assays for the immunodetection of disease-specific target antigens.
- Antibody Conjugation Conjugate an enzyme, biotin, or fluorophore to an antibody.
- Antibody Detection Quantitate, localize and visualize proteins and other antigens.
- Antibody Products Purchase antibody, antibody pair kit or ELISA kit.
- Antibody Purification Purify multiple antibody types including IgG, IgM, IgA and IgY.
- Antibody Sequencing Sequence cDNA encoding variable heavy (VH) and variable light (VL) domains of a hybridoma cell line.
Show all 12 in Antibodies
- Biotin-Antibody Conjugation Biotinylate an antibody for improved detection.
- In Vitro Monoclonal Antibody Production Generate monoclonal antibodies in vitro using cultured antibody-secreting hybridoma cell lines.
- Phosphospecific Antibodies Create antibodies to detect phosphorylated protein targets.
- Polyclonal Antibody Production Generate polyclonal antibodies in vivo using evolutionary distant animal species.
- Polyclonal/Monoclonal Antibody Production Generate polyclonal or monoclonal antibodies in a range of animal species, over-express antibodies in cultured cells.
- Single Chain Variable Fragment (scFv) Create an antigen-specific antibody derivative using a linker to join a heavy and a light variable chain.
Biomarkers
- Anatomic Pathology Do macroscopic, microscopic, biochemical, immunologic and molecular examination of organs and tissues.
- Biomarker Clinical Validation Evaluate the predictive ability of a candidate biomarker for a disorder.
- Biomarker Discovery Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.
- Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
- Cerebrospinal Fluid Analysis Use CSF to detect or monitor a variety of nervous system diseases or conditions.
- Diagnostic Biomarkers Discovery Identify candidate biomarkers indicative of the presence of a disorder.
Show all 16 in Biomarkers
- Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
- Fluorescent In Situ Hybridization Use FISH to identify abnormal chromosome structures and to quantify specific DNA sequences.
- Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
- Immunohistochemistry Examine the toxic effects of pre-clinical compounds in small animal and patient histological samples.
- Myeloperoxidase Testing Detect inflammatory markers and determine the risk for atherosclerosis or arterial plaque rupturing.
- Predictive Biomarkers Discovery Identify candidate biomarkers suggestive of a response to a treatment.
- Prognostic Biomarkers Discovery Identify candidate biomarkers representative of disease progression without treatment.
- Single Cell quantitative Real Time-PCR Assess gene expression levels and patterns in a single cell.
- Single Cell Transcriptome Sequencing Detect distinct, rare or abnomal cell types in a heterogenous population.
- TUNEL Assay Detect in situ DNA fragmentation.
Show all 62 services
Cell Culture and Characterization
- Single Cell DNA Sequencing Examine genetic variations in a single cell.
Chemical and Compound Analysis
- Ion Exchange Chromatography Separate and detect analytes.
- Protein Crystallization Create high quality protein-ligand crystals for x-ray diffraction studies.
- Protein Separation and Detection Separate proteins based on properties such as solubility, adsorption or size differences.
- Size Exclusion Chromatography Separate and identify analytes based on their molecular size.
DNA & RNA
- RNA Profiling Quantify the expression levels of mRNA transcripts, enabling the determination of gene expression patterns.
- RNAscope In Situ Assays Profile single-cell gene expression in situ.
- Single Cell RNA Sequencing Quantify mRNA variants in a single cell.
- Target Gene Expression Measure expression of a target gene at the protein, RNA and DNA level.
- Tissue Microarray Screen large numbers of tissues for the presence or absence of specific molecular markers.
In Vitro Assays
- Annexin V Apoptosis Assay Detect and quantify apoptotic cells based on loss of membrane asymmetry.
- Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
- Caspase Assay Detect early to mid stage apoptosis or differentiate apoptosis from necrosis.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
Protein Sciences
- Affinity Tag Purification Purify proteins under physiological conditions at their native cellular levels.
- Bacterial Expression Produce milligram, gram and kilogram amounts of proteins.
- Cytokines Find recombinant cytokines or cytokine assays.
- ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
- Fusion Proteins Use recombinant DNA technology to create and express proteins derived from more than one gene.
- Immunoprecipitation Precipitate a protein of interest out of solution using an antibody to which it binds.
Show all 17 in Protein Sciences
- Insect Expression Use baculovirus infected cells or non-lytic cell systems to produce glycosylated proteins.
- Large Scale Protein Production Produce large amounts of protein using fermentors, wave mixers, bioreactors, and large-scale purification workflows.
- Mammalian Expression Express high yields of recombinant proteins, antibodies, virus, viral-subunit proteins and gene-therapy vectors.
- Protein Conjugation Create tagged monoclonals, polyclonal and recombinant proteins.
- Protein Identification Uncover or confirm the identity of a protein.
- Protein Production Produce recombinant protein molecules in prokaryotic or eukaryotic systems.
- Protein Products Find native and recombinant proteins and peptides.
- Protein Purification Isolate native or recombinant proteins from a sample.
- Protein Services Consulting Expert advice to evaluate and analyze protein function and expression.
- Recombinant Proteins Use recombinant DNA to produce proteins in vivo or in vitro.
- Western Blots Detect specific proteins in a sample of tissue homogenate or extract.
REACH Services
- OECD 489: In Vivo Mammalian Alkaline Comet Assay Measure the mitogenic and genotoxic potential of test compounds.
Scientific Data Services
- Small RNA Gene Expression Quantify and analyze miRNA, piRNA, siRNA as well as other small nuclear RNAs from small-RNA-seq raw input data sets.
Other services
- New Request
- Website
- www.bio-techne.com
Where it operates
Sites by country, with the cities in each.
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United Kingdom 2 sites
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United States 2 sites
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