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RIC Belgium - RIC biologics

RIC Belgium - RIC biologics is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country.

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Sites 2
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Small business

Agricultural Sciences Research & Development

  • Method Development & Validation Engineer sensitive and selective methods that meet GLP validation requirements to access different agrochemical properties

Antibodies

  • Antibody Detection Quantitate, localize and visualize proteins and other antigens.
  • Antibody Purification Purify multiple antibody types including IgG, IgM, IgA and IgY.
  • Direct Antibody Labeling Conjugate a primary antibody to a label for direct antigen detection.

Biomarkers

  • Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
  • Lipid Kinase Assays Use biochemical, cell-based or in vivo assays to measure lipid kinase activity.
  • Metabolomics Biomarker Discovery Identify and quantitate metabolite biomarkers in blood, urine, CSF and bodily fluids.
  • Protein Glycosylation Mapping Technique Map glycosylation sites in proteins using liquid chromatography and mass spectrometry.

Chemical and Compound Analysis

  • Amino Acid Analysis (AAA) Determine protein quantities, relative compositions and amino acid content profiles.
  • API Physical Characteristics Characterize physical and chemical properties of new drug molecules to develop safe, effective, and stable dosage forms.
  • Chemical Stability Measure the stability of small molecules in solution.
  • Denaturing High Performance Liquid Chromatography Separate mixtures of denatured and reannealed oligos to identify single nucleotide substitutions, deletions and insertions.
  • Dynamic Light Scattering Determine the size of particles and extent of molecular aggregation in a suspension.
  • Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
Show all 24 in Chemical and Compound Analysis 18 more
  • Excipient Compatibility Test excipients for drug formulation, effects of temperature, time, humidity, pH and light exposure as well as excipient release.
  • Gas Chromatography Gas chromatography is an analytical technique that separates, identifies, and quantifies compounds in a mixture
  • High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
  • Immunoaffinity Chromatography Use antibody-antigen interactions to isolate and concentrate analytes.
  • Ion Exchange Chromatography Separate and detect analytes.
  • Liquid Chromatography Separate substances using a mobile and stationary phase.
  • Nano-High Performance Liquid Chromatography Separate and detect low levels of analytes.
  • Non GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
  • Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
  • Particle Size Analysis Measure particle size distribution and characterize particle size, porosity and composition.
  • Photostability Measure drug degradation rates after exposure to various light sources.
  • Process Residual Impurities Detection Measure trace levels of impurities.
  • Protein Binding HPLC Uses high pressure liquid chromatography to separate protein-drug complexes.
  • Protein Separation and Detection Separate proteins based on properties such as solubility, adsorption or size differences.
  • Protein Structure Determine the three dimensional structure of a protein by NMR or x-ray crystallography.
  • Sample Bioanalysis Determination of concentration of an analyte in biological sample.
  • Size Exclusion Chromatography Separate and identify analytes based on their molecular size.
  • Structural Chemistry Examine the relationship between protein structure and function.
Show all 77 services 63 more

Chemistry, Manufacturing and Controls (CMC)

  • Analytical Development and Validation Request services related to Analytical Development and Validation
  • API/ Excipients Compatibility Studies Delineate real and possible interactions between potential formulation excipients and the API as an important risk reduction exercise early in formulation development.
  • Chemistry Manufacturing Controls Access contract manufacturing and regulatory guidance in setting specifications and drug dosage formulations.
  • Drug Formulation Combine substances including the active drug into a final product with the desired metabolic and therapeutic properties.
  • Drug Product Stability Use accelerated stress conditions to determine degradation pathways and identify manufacturing issues.
  • Excipients Acquire synthetic or natural inert components to formulate therapeutic agents.
Show all 7 in Chemistry, Manufacturing and Controls (CMC) 1 more
  • Forced Degradation Run light, heat, humidity, acid hydrolysis and oxidation tests to evaluate substance degradation.

Data Science/Bioinformatics

  • In Silico Protein Modification Analysis Use computational methods to predict the behavior of modified proteins.

Discovery Chemistry

  • Certified Standards Find certified standards for assays, tests and services.
  • Impurity Synthesis Use high resolution MS or NMR to eliminate intermediates or organic byproducts and determine impurity content.
  • LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
  • Method Development and Validation Develop and validate methods for synthesis and scale up of drug candidates.

DNA & RNA

  • Capillary Electrophoresis Separate ng quantities of DNA to single base resolution.
  • Expression Profiling Measure the the expression of thousands of genes at once to create a global picture of cellular function.

Drug Development

  • Assay Development Consulting Request consultant services measuring the activity of a drug or biochemical in an organism or organic sample.

In Vitro ADME

  • Plasma Stability Assay Determine degradation rate of drug candidates in plasma.
  • Reference Standards Find reference standards for assays, tests and services.

In Vitro Assays

  • Assay Development Construct or create new assays or modify existing ones.
  • Glycomics Glycomics is the comprehensive study of glycans, in a biological system, such as a cell or organism

In Vitro Pharmacology

  • G-Protein Coupled Receptor (GPCR) Assays Detect ligand binding, receptor dimerization and downstream signal transduction events.
  • Protease Assay Measure protease activity in biochemical and cell-based assays.

Nanotechnology

  • Liposomes Create artificial spherical vesicles that can be used as a vehicle for administration of drugs.

New Product Development

  • Vitamins Analysis Analyze vitamins in foods and dietary supplements either by HPLC or titration.

Other Specialty Toxicology

  • Raw Materials Testing Verify that raw materials are sterile and not contaminated by mycoplasma, virus or other microorganisms.
  • Residual DNA Analysis Measure contaminants found in therapeutics like biologicals and biosimilars that are produced in cells.

Pharmacovigilance

  • GxP Compliance Monitoring Ensure products or services adhere to a set minimum standard.

Protein Sciences

  • Affinity Tag Purification Purify proteins under physiological conditions at their native cellular levels.
  • Carbohydrate Structure Characterization Use analytical tools to elucidate carbohydrate structure and physiochemical properties.
  • ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
  • Host Cell Protein Analysis Measure contamination of biologics with host proteins by using sequencing, chromatography and the LAL test.
  • LCMS/MS Analysis Liquid chromatography–mass spectrometry is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography with the mass analysis capabilities of mass spectrometry.
  • Mass Spectrometry-Based Proteomics Detect histone post-translational modifications (hPTMs), histone variants, and interactomes at chromatin regions.
Show all 15 in Protein Sciences 9 more
  • Phosphorylation Analysis Identify phosphorylation sites in target proteins.
  • Protein Binding Determine drug-protein binding interactions
  • Protein Conjugation Create tagged monoclonals, polyclonal and recombinant proteins.
  • Protein Expression Produce recombinant proteins in prokaryotic or eukaryotic systems.
  • Protein Identification Uncover or confirm the identity of a protein.
  • Protein Post-translational Modification Analysis Measure glycosylation, phosphorylation, sulfation, ubiquitination, methylation and acetylation.
  • Protein Purification Isolate native or recombinant proteins from a sample.
  • Protein Services Consulting Expert advice to evaluate and analyze protein function and expression.
  • Proteomics Do large-scale experimental analysis of proteins focused on understanding structure and function.

Scientific Data Services

  • Metabolomics Data Analysis Use metabolites to identify any potential biomarkers or novel therapeutic targets that may play a role in the mechanisms responsible for the progression of a disease.

Testing Services

  • Accelerated Stability Determine shelf life of drug formulations by comparing API breakdown at elevated temperature.
  • Elevated Temperature Stability Determine the stability of a product at elevated temperature.
  • Freeze-Thaw Testing Use freeze-thaw cycling to measure the long-term durability of cosumer products.

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • Belgium Kortrijk 2 sites

Source: Scientist.com supplier network (site locations)

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