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Research supplier
Advanced Cell Diagnostics, Inc. (ACD)
Advanced Cell Diagnostics, Inc. (ACD) is listed as a mid sized business research supplier in the Scientist.com network, with 7 sites in 6 countries and 1 service area.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Mid sized business
Biomarkers
- Biomarker Clinical Validation Evaluate the predictive ability of a candidate biomarker for a disorder.
- Biomarker Discovery Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.
- Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
- Digital Pathology Acquire, manage and interpret pathology information generated from a digital image of a slide preparation of cells or tissue.
Chemical and Compound Testing
- Clinical Pathology Diagnose disease based on the laboratory analysis of bodily fluids, such as blood, urine and tissues.
Companion Diagnostics
- Pancreatic Cancer CDx Design and validate companion diagnostics for pancreatic cancer that help select the most appropriate patients, identify patients at increased risk, or monitor treatment effectiveness.
Disease Models
- Inflammatory Bowel Disease Models Measure IBD symptom severity, cytokine levels and body weight, and evaluate IHC and Ariol images.
- Neuroscience Models Test therapeutic efficacy of drug candidate in neurological disease model.
- Pulmonary Fibrosis Models Measure therapeutic endpoints in animal models of pulmonary fibrosis.
DNA & RNA
- In Situ Hybridization Localize specific nucleic acid targets using labeled complementary probes.
- RNA Amplification Produce RNA from pre-clinical and clinical samples for use in gene expression studies.
- RNAscope In Situ Assays Profile single-cell gene expression in situ.
Show all 24 services
Human Biological Samples
- HBS: Human Biological Samples Request human biosamples including tissues, blood, serum, bone marrow, tissue microarrays, etc.
- HBS: Human Biological Samples - VMS Request human biosamples including tissues, blood, serum, bone marrow, tissue microarrays, etc.
In Vitro Pharmacology
- Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.
In Vivo Pharmacokinetics
- In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
- Ocular Pharmacokinetic (PK) Screening - Monkey / Non-human Primate Conduct a pharmacokinetic screening study in monkeys/non-human primates that measures the absorption, distribution, metabolism and excretion of your compound following ocular administration.
- Ocular Pharmacokinetic (PK) Screening - Other Species Conduct a pharmacokinetic screening study in other species that measures the absorption, distribution, metabolism and excretion of your compound following ocular administration.
- Pharmacokinetic (PK) Screening - Monkey / Non-human Primate Conduct a pharmacokinetic screening study in monkeys/non-human primates that measures the absorption, distribution, metabolism and excretion of your compound.
- Pharmacokinetic (PK) Screening - Mouse Run pharmacokinetic studies in mice that measure a drug's absorption, distribution, metabolism and excretion.
- Pharmacokinetic (PK) Screening - Other Species Run pharmacokinetic studies in large animals that measure a drug's absorption, distribution, metabolism and excretion.
Oncology Models
- Xenograft Models Measure therapeutic endpoints in cancer models using tumor cells transplanted from a donor of a different species.
Other services
- Integrated Human Biospecimen Package Utilize a Human Biospecimen Pipeline Package to process or characterize Human Biological Samples including: Sample Preparation, Histochemistry, Hybridization, Sequencing, Cell Based Assays, and Sample Bioanalysis from...
- New Request
Service areas:
Where it operates
Sites by country, with the cities in each.
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Switzerland 2 sites
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France 1 site
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Germany 1 site
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Ireland 1 site
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United Kingdom 1 site
Showing 5 of 6 countries.
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Advanced Cell Diagnostics (ACD) specializes in molecular pathology and develops cell/tissue based diagnistic assays for personalized medicine. RNAscope® is a proprietary RNA in situ hybridization (ISH) assay based on ACD patented signal amplification and background suppression technology which advances RNA biomarker analysis in tissues and cells. Unique to this technology, RNAscope® delivers quantitative, sensitive and specific molecular detection of RNA species on a cell-by-cell basis with morphological context in a single assay. This enables researchers to visualize which genes are...
Show the full description
Advanced Cell Diagnostics (ACD) specializes in molecular pathology and develops cell/tissue based diagnistic assays for personalized medicine. RNAscope® is a proprietary RNA in situ hybridization (ISH) assay based on ACD patented signal amplification and background suppression technology which advances RNA biomarker analysis in tissues and cells. Unique to this technology, RNAscope® delivers quantitative, sensitive and specific molecular detection of RNA species on a cell-by-cell basis with morphological context in a single assay. This enables researchers to visualize which genes are expressed, localize where they are expressed, and quantify the level of expression.
KEY BENEFITS
- MOLECULAR DETECTION
Distinguish between RNA molecules of up to 85% sequence homology and with single copy detection
- MORPHOLOGICAL CONTEXT
Visualize gene expression within individual cells in all regions of the tissue
- QUANTITATIVE
Determine the number of RNA transcripts per cell and compare different regions of the tissue
or across samples
- UNIVERSAL
Apply to virtually ANY gene from ANY genome in ANY tissue
- SCALABLE
Scale up with automation for routine high-throughput analysis
- Website
- www.acdbio.com
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