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Prince Felipe Research Centre (CIPF)
Prince Felipe Research Centre (CIPF) is listed as an academic core research supplier in the Scientist.com network, with 1 site in 1 country and 2 service areas.
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Sites
1
Countries
1
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Academic core
Bioimaging
- Cryo Electron Microscopy Examine the 3D structure of biological complexes and organelles.
- Electron Microscopy Examine the fine structures of molecules, cells and tissues with sub-nanometer resolution.
- Luminescence Imaging Monitor biological processes and pathologies using reporter proteins such as firefly and Renilla luciferase.
- Magnetic Resonance Imaging Use MRI to obtain chemical and physical information about molecules and map the internal structure of an object.
- Microscopy Use microscopy to analyze surfaces of biological materials and to develop 3D images of biological structures.
Biomarkers
- Anatomic Pathology Do macroscopic, microscopic, biochemical, immunologic and molecular examination of organs and tissues.
- Basic Metabolic Profiling Set up assays that monitor drug metabolite formation after administration of drug to an animal model or patient.
- Biomarker Analytical Validation Assess and optimize the characteristics of a candidate biomarker to ensure reproducibility and consistency.
- Biomarker Discovery Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.
- Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
- Cell Migration Assays Measure chemotaxis, haptotaxis, transmigration and wound-healing.
Show all 19 in Biomarkers
- Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
- Complete Metabolic Panel Testing Detect electrolyte or glucose imbalance to identify or monitor related disorders.
- Diagnostic Biomarkers Discovery Identify candidate biomarkers indicative of the presence of a disorder.
- Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
- Fluorescent In Situ Hybridization Use FISH to identify abnormal chromosome structures and to quantify specific DNA sequences.
- Histopathology Evaluate slide preparation of cells or tissues for abnormal features.
- Metabolomics Biomarker Discovery Identify and quantitate metabolite biomarkers in blood, urine, CSF and bodily fluids.
- Multi-Omics Study Use an integrated multi-omics study to understand a disease mechanism.
- Paraffin-based Histology Perform sectioning and histological analysis of wax-embedded samples.
- Predictive Biomarkers Discovery Identify candidate biomarkers suggestive of a response to a treatment.
- Prognostic Biomarkers Discovery Identify candidate biomarkers representative of disease progression without treatment.
- Single Cell Isolation Isolate single cells for subsequent single-cell analysis.
- Single Cell quantitative Real Time-PCR Assess gene expression levels and patterns in a single cell.
Cell Culture and Characterization
- Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
- Cell and Tissue Histology Prepare and stain frozen, fixed and embedded (FFPE) tissue samples.
- Cell Culture Culture primary or immortalized cell lines.
- Histology Examine by microscopy the anatomy of cells and tissues of clinical patients and animal models.
- In Vitro Hydrogel-Based Culture of PDXs Enable the extended laboratory culture of cancer PDXs and other primary cells in 3D.
- Karyotyping Evaluate the number and appearance of chromosomes in the nucleus of a eukaryotic cell.
Show all 8 in Cell Culture and Characterization
- Single Cell DNA Sequencing Examine genetic variations in a single cell.
- Stem Cell Differentiation Acquire specialized cells from differentiated stem cells.
Show all 77 services
Chemical and Compound Analysis
- NMR Methods Use nuclear magnetic resonance spectroscopy to identify drug intermediates.
- NMR Structure Determine molecular structure, identify chemical impurities and validate sample integrity.
- Scanning and Transmission Electron Microscopy Examine the fine structures of molecules, cells and tissues with sub-nanometer resolution.
- Structure Determination Determine the three-dimensional structure of proteins in the presence or absence of ligands.
- Total Internal Reflection Fluorescence Microscopy Visualize single molecule fluorescence at a surface to produce high quality images with low background.
Chemistry, Manufacturing and Controls (CMC)
- Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
Clinical Consulting
- Biomarker Services Consulting Expert advice to conduct solutions for evaluating normal/abnormal biological conditions and characteristics within the body.
Disease Models
- Behavioral Testing Models Investigate sensory-motor and emotional functions, social behavior and day-night activity.
- Cognition Models Measure therapeutic endpoints in animal models of cognition.
- In Vivo Technologies Models Carry out EEGs, cognition assessment, microdialysis, electrophysiology, MRI, ultrasound and tomographic analysis.
- Morris Water Maze Investigate spatial learning and memory in rodents.
- Myelination Models Measure therapeutic endpoints in animal models with induced myelination, remyelination or developmental myelination.
- Object Recognition Measure spatial navigation, working memory and cognitive function in animal models.
DNA & RNA
- Capillary Electrophoresis Separate ng quantities of DNA to single base resolution.
- ChIP-Sequencing Use chromosome immunoprecipitation to identify DNA-protein binding sites in a genome.
- ChIP-sequencing Profiling Identify where a protein is binding to DNA on a genome-wide scale.
- Nucleic Acid Hybridization Use a nucleic acid probe to identify complementary sequences.
- Quantitative RT PCR Use quantitative reverse transcription polymerase chain reaction to measure absolute and relative mRNA abundance.
- Sanger Sequencing Sequence single strand DNA fragments using DNA Polymerase.
Show all 7 in DNA & RNA
- Single Cell RNA Sequencing Quantify mRNA variants in a single cell.
In Vitro ADME
- Metabolite Identification and Profiling Estimate drug candidate metabolites after administration of drug to an animal or human subject.
In Vitro Assays
- Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
- Cell Based Assays Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
- Cell Proliferation Measure cell number, cell viability and cell division.
- High Content Screening Analyze whole cells or components of cells with simultaneous readout of several parameters.
- HTS Assay Development Develop assays to use in high throughput screening.
- Stem Cell Differentiation Microscopy Assay› Elucidate mechanisms of stem cell renewal and differentiation in vitro using fluorescence microscopy.
In Vitro Pharmacology
- Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
- High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
- In Vitro Enzyme Activity Assay Development Develop new in vitro enzyme activity assays or modify existing ones.
- Target Identification Identify the target(s) of a biologically active substance.
- Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.
In Vitro Toxicology
- Cytotoxicity Test for effects on cell viability and proliferation
Lab Supplies, Facilities, and Equipment
- Biobanking Store and track biological samples.
Model Development
- Lewis Rat Use a single animal species to create one or more disease models for metastatic cancer, hematopoiesis and anemia.
- SCID/BG Mouse Use a single animal species to create one or more disease models for metastatic cancer.
Nanotechnology
- Drug Delivery Technology Create microstructures that enhance drug metabolism properties.
- Nanoparticle Synthesis Create nano-level structures with unique features.
Oncology Models
- Athymic Mouse Use a single animal species to create one or more disease models for cachexia and spontaneous cancer.
- Oncology Models Use model organisms to test the therapeutic efficacy of cancer drug candidates.
- Xenograft Models Measure therapeutic endpoints in cancer models using tumor cells transplanted from a donor of a different species.
Protein Sciences
- Proteomics Do large-scale experimental analysis of proteins focused on understanding structure and function.
Safety Pharmacology
- Telemetry Use implantable or external devices to study physiological parameters in model organisms
Other services
- Implantable Telemetry for Large Animals Use implantable telemetry to study physiological parameters in large animals, such as dogs, primates, swine, sheep, horses, and cattle among others.
- New Request
Service areas:
Biology
Pharmacology
Where it operates
Sites by country, with the cities in each.
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Spain 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Prince Felipe Research Centre (CIPF) focuses on research in regenerative medicine, protein chemistry, structural biochemistry, gene expression, and bioinformatics.
- Website
- www.cipf.es
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