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A&M StabTest GmbH
A&M StabTest GmbH is listed as a mid sized business research supplier in the Scientist.com network, with 1 site in 1 country.
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1
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Mid sized business
Antibodies
- Antibody Protein De Novo Sequencing Sequence antibody proteins using multiple enzyme digestion and high-resolution LC-MS/MS.
- Antibody Sequencing Sequence cDNA encoding variable heavy (VH) and variable light (VL) domains of a hybridoma cell line.
- Antibody-Dependent Cell-Mediated Cytotoxicity Request services related to cell-mediated immune defense.
- Immunodetection Use antibodies to identify a protein or antigen.
Biomarkers
- Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
- Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
- Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
- Proteocarta™ HCP Detect Services Identify and track host cell proteins (HCP) with mass spectrometry for higher sensitivity and coverage.
Cell Culture and Characterization
- Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
Chemical and Compound Analysis
- Atomic Absorption Analysis Measure the elemental composition of a diverse array of samples.
- Chemical Stability Measure the stability of small molecules in solution.
- Denaturing High Performance Liquid Chromatography Separate mixtures of denatured and reannealed oligos to identify single nucleotide substitutions, deletions and insertions.
- Dissolution Profiling Measure release of API from formulation (tablet or capsules) under GMP guidelines.
- Dynamic Light Scattering Determine the size of particles and extent of molecular aggregation in a suspension.
- Headspace Gas Chromatography Analyze volatile organic compounds (VOCs) partitioned above the liquid/solid phase of a sample.
Show all 17 in Chemical and Compound Analysis
- High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
- Ion Exchange Chromatography Separate and detect analytes.
- Liquid Chromatography Separate substances using a mobile and stationary phase.
- Particle Size Analysis Measure particle size distribution and characterize particle size, porosity and composition.
- Photostability Measure drug degradation rates after exposure to various light sources.
- Process Residual Impurities Detection Measure trace levels of impurities.
- Protein Separation and Detection Separate proteins based on properties such as solubility, adsorption or size differences.
- Size Exclusion Chromatography Separate and identify analytes based on their molecular size.
- Static Light Scattering Use scattered light intensity to determine the average molecular weight of biopolymers.
- Structural Chemistry Examine the relationship between protein structure and function.
- Structural Elucidation Determine chemical structure of a compound. Characterization techniques include mass spectrometry, infrared spectroscopy and X-ray crystallography.
Show all 69 services
Chemistry, Manufacturing and Controls (CMC)
- API and Drug Product Stability Testing API and Drug Product Stability Testing.
- API and drug product storage and release API and drug product storage and release
- API Stress Testing Studies Develop analytical methods to predict stability problems and identify degradation products/pathways under forced degradation conditions.
- Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
- Drug Product Stability Use accelerated stress conditions to determine degradation pathways and identify manufacturing issues.
- Drug Substance and Drug Product Characterization and Manufacturing Drug Substance and Drug Product Characterization and Manufacturing.
Show all 8 in Chemistry, Manufacturing and Controls (CMC)
- Forced Degradation Run light, heat, humidity, acid hydrolysis and oxidation tests to evaluate substance degradation.
- ICH-compliant stability testing Perform ICH-compliant stability testing
Discovery Chemistry
- Extractable and Leachable Assessment Quantify potential impurities from container closures & packaging.
- LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
- Leachable and extractable testing Leachable and extractable testing
- Method Development and Validation Develop and validate methods for synthesis and scale up of drug candidates.
- UV and IR Profiling Analyze the integrity of a compound or large biomolecule.
DNA & RNA
- Capillary Electrophoresis Separate ng quantities of DNA to single base resolution.
- Poly (A) tail Length Profiling (PAL-Seq) Conduct high-throughput sequencing of individual mRNA poly (A) tails.
- qPCR Analysis Measure the accumulation of PCR products in real time.
- Quantitative RT PCR Use quantitative reverse transcription polymerase chain reaction to measure absolute and relative mRNA abundance.
Food Safety & Regulations
- Water Activity Determine water activity in consumer healthcare products involving a USP or FCC monograph.
In Vitro Assays
- Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
- Assay Development Construct or create new assays or modify existing ones.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Cell Proliferation Measure cell number, cell viability and cell division.
- In Vitro Efficacy Test Use in vitro models to test the efficacy of your products.
- Lipid Detection Use in vitro methods to identify lipid droplets and any associated proteins.
Show all 12 in In Vitro Assays
- Lipolysis Measure the hydrolysis of triglycerides into glycerol and free fatty acids.
- Oxidative Burst Examine the release of reactive oxygen species (ROS) from neutrophils and other immune cells.
- Reactive Species Assays Use biochemical, cell-based or in vivo assays to detect and evaluate the effects of reactive species.
- Serine Protease Assay Detect apoptosis by measuring protease activity.
- Thrombin Generation Tests Measure the tendency of a plasma sample to form thrombin upon the initiation of coagulation.
- Virus Detection Assays Use ultra-sensitve methods to reliably detect low level viruses.
In Vitro Pharmacology
- Protease Assay Measure protease activity in biochemical and cell-based assays.
In Vitro Toxicology
- ADCC and CDC Assay Services Measure toxicity of antibodies.
- Cytotoxicity Test for effects on cell viability and proliferation
Other Specialty Toxicology
- Residual DNA Analysis Measure contaminants found in therapeutics like biologicals and biosimilars that are produced in cells.
Protein Sciences
- FRET/BRET Detect the location of proteins in living cells and their ability to interact with other proteins.
- Host Cell Protein Analysis Measure contamination of biologics with host proteins by using sequencing, chromatography and the LAL test.
- LCMS/MS Analysis Liquid chromatography–mass spectrometry is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography with the mass analysis capabilities of mass spectrometry.
- Protein Identification Uncover or confirm the identity of a protein.
- Protein Post-translational Modification Analysis Measure glycosylation, phosphorylation, sulfation, ubiquitination, methylation and acetylation.
- Quantitative MS Quantify small and large molecules in the pg/ml range
Testing Services
- Freeze-Thaw Testing Use freeze-thaw cycling to measure the long-term durability of cosumer products.
- Package Compatibility Tests Ensure that the consumer product is not adversely affected by the package components and vice versa.
- Real-time Stability Test Assure stability and physical integrity of consumer products in real-time conditions.
- Website
- www.am-labor.de/en
Where it operates
Sites by country, with the cities in each.
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Germany 1 site
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