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Clinical trial

Open-Label, Dose-Escalation Study Evaluating the Safety of a Single Administration of an Adeno-Associated Virus Vector Encoding Human Aquaporin-1 to One Parotid Salivary Gland in Individuals With Irradiation-Induced Parotid Salivary Hypofunction

NCT02446249 is registered in ClinicalTrials.gov with MeiraGTx, LLC as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
Open-Label, Dose-Escalation Study Evaluating the Safety of a Single Administration of an Adeno-Associated Virus Vector Encoding Human Aquaporin-1 to One Parotid Salivary Gland in Individuals With Irradiation-Induced Parotid Salivary Hypofunction
Lead sponsor
MeiraGTx, LLC
Phase
Phase 1
Overall status
Completed
Start date
May 4, 2015
Completion date
August 10, 2026
Enrollment
17 (actual)
Sites
1

Conditions

As the registry lists them; a condition with its own page is linked.

radiation induced xerostomia, salivary hypofunction, squamous cell head and neck cancer