Clinical trial
An Open-Label, Multicenter, Dose-Escalation, Phase Ia/Ib Study to Evaluate Safety, Pharmacokinetics, and Therapeutic Activity of RO6874281, an Immunocytokine Consisting of Interleukin 2 Variant (IL-2v) Targeting Fibroblast Activation Protein-α (FAP), as a Single Agent (Part A) or in Combination With Trastuzumab or Cetuximab (Part B or C)
NCT02627274 is registered in ClinicalTrials.gov with Hoffmann-La Roche as lead sponsor.
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Registry record
As filed in ClinicalTrials.gov.
- Title
- An Open-Label, Multicenter, Dose-Escalation, Phase Ia/Ib Study to Evaluate Safety, Pharmacokinetics, and Therapeutic Activity of RO6874281, an Immunocytokine Consisting of Interleukin 2 Variant (IL-2v) Targeting Fibroblast Activation Protein-α (FAP), as a Single Agent (Part A) or in Combination With Trastuzumab or Cetuximab (Part B or C)
- Lead sponsor
- Hoffmann-La Roche
- Phase
- Phase 1
- Overall status
- Completed
- Start date
- December 7, 2015
- Completion date
- November 10, 2022
- Enrollment
- 134 (actual)
- Sites
- 26
Conditions
As the registry lists them; a condition with its own page is linked.
breast cancer, cancer of head and neck, solid tumor