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Clinical trial

International Phase I/II Expansion Trial of the MEK Inhibitor Selumetinib in Combination With Dexamethasone for the Treatment of Relapsed/Refractory RAS-pathway Mutated Paediatric and Adult Acute Lymphoblastic Leukaemia

NCT03705507 is registered in ClinicalTrials.gov with University of Birmingham as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
International Phase I/II Expansion Trial of the MEK Inhibitor Selumetinib in Combination With Dexamethasone for the Treatment of Relapsed/Refractory RAS-pathway Mutated Paediatric and Adult Acute Lymphoblastic Leukaemia
Lead sponsor
University of Birmingham
Phase
Phase 1/2
Overall status
Terminated
Start date
May 18, 2018
Completion date
May 3, 2023
Enrollment
12 (actual)
Sites
17

Conditions

As the registry lists them; a condition with its own page is linked.

acute lymphoblastic leukemia, acute lymphoblastic leukemia recurrent, acute lymphoblastic leukemia, adult, acute lymphoblastic leukemia, in relapse, acute lymphoblastic leukemia, pediatric