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Clinical trial

A 3-Part, Randomized, Double-Blind, Placebo-Controlled Phase 2 Study to Evaluate Safety and Efficacy of Avapritinib (BLU-285), a Selective KIT Mutation-Targeted Tyrosine Kinase Inhibitor, in Indolent and Smoldering Systemic Mastocytosis With Symptoms Inadequately Controlled With Standard Therapy

NCT03731260 is registered in ClinicalTrials.gov with Blueprint Medicines Corporation as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A 3-Part, Randomized, Double-Blind, Placebo-Controlled Phase 2 Study to Evaluate Safety and Efficacy of Avapritinib (BLU-285), a Selective KIT Mutation-Targeted Tyrosine Kinase Inhibitor, in Indolent and Smoldering Systemic Mastocytosis With Symptoms Inadequately Controlled With Standard Therapy
Lead sponsor
Blueprint Medicines Corporation
Phase
Phase 2
Overall status
Active, not recruiting
Start date
April 16, 2019
Completion date
June 23, 2027
Enrollment
251 (actual)
Sites
49

Conditions

As the registry lists them; a condition with its own page is linked.

indolent systemic mastocytosis