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Clinical trial

Open-Label, Phase 1/2 Study Evaluating the Relative Bioavailability/Bioequivalence of Different Formulations of Selinexor, the Impact of Hepatic Impairment on Selinexor Pharmacokinetics, and the Tolerability and Antitumor Activity of Selinexor Combination Treatment (SPRINT)

NCT04256707 is registered in ClinicalTrials.gov with Karyopharm Therapeutics Inc as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
Open-Label, Phase 1/2 Study Evaluating the Relative Bioavailability/Bioequivalence of Different Formulations of Selinexor, the Impact of Hepatic Impairment on Selinexor Pharmacokinetics, and the Tolerability and Antitumor Activity of Selinexor Combination Treatment (SPRINT)
Lead sponsor
Karyopharm Therapeutics Inc
Phase
Phase 1/2
Overall status
Completed
Start date
February 9, 2020
Completion date
July 31, 2024
Enrollment
80 (actual)
Sites
11

Conditions

As the registry lists them; a condition with its own page is linked.

colorectal cancer (crc), non-small cell lung carcinoma (nsclc), other solid tumors