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Clinical trial

Phase I/IIa, First-in-human, Open-label, Dose Escalation Trial With Expansion Cohorts to Evaluate Safety and Preliminary Efficacy of CLDN6 CAR-T With or Without CLDN6 RNA-LPX in Patients With CLDN6-positive Relapsed or Refractory Advanced Solid Tumors

NCT04503278 is registered in ClinicalTrials.gov with BioNTech Cell & Gene Therapies GmbH as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
Phase I/IIa, First-in-human, Open-label, Dose Escalation Trial With Expansion Cohorts to Evaluate Safety and Preliminary Efficacy of CLDN6 CAR-T With or Without CLDN6 RNA-LPX in Patients With CLDN6-positive Relapsed or Refractory Advanced Solid Tumors
Lead sponsor
BioNTech Cell & Gene Therapies GmbH
Phase
Phase 1
Overall status
Active, not recruiting
Start date
September 16, 2020
Completion date
August 31, 2041
Enrollment
214 (estimated)
Sites
12

Conditions

As the registry lists them; a condition with its own page is linked.

solid tumor