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Clinical trial

A Randomized, Multicenter, Open Label, Phase I/II Study to Evaluate the Safety, Clinical and Biological Activity of a Humanized Monoclonal Antibody Targeting Netrin-1 (NP137) in Combination with Carboplatin Plus Paclitaxel And/or Pembrolizumab in Patients with Locally Advanced/metastatic Endometrial Carcinoma or Cervix Carcinoma Progressing/relapsing After At Least One Prior Systemic Chemotherapy.

NCT04652076 is registered in ClinicalTrials.gov with NETRIS Pharma as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Randomized, Multicenter, Open Label, Phase I/II Study to Evaluate the Safety, Clinical and Biological Activity of a Humanized Monoclonal Antibody Targeting Netrin-1 (NP137) in Combination with Carboplatin Plus Paclitaxel And/or Pembrolizumab in Patients with Locally Advanced/metastatic Endometrial Carcinoma or Cervix Carcinoma Progressing/relapsing After At Least One Prior Systemic Chemotherapy.
Lead sponsor
NETRIS Pharma
Phase
Phase 1/2
Overall status
Active, not recruiting
Start date
December 14, 2020
Completion date
July 30, 2026
Enrollment
240 (estimated)
Sites
15

Conditions

As the registry lists them; a condition with its own page is linked.

cervix carcinoma, endometrial carcinoma