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Clinical trial

A Phase II Open-Label Study for the Comprehensive Analysis of Predictors of the Treatment With Pembrolizumab and Olaparib in Patients With Unresectable or Metastatic HER2 Negative Breast Cancer and a Deleterious Germline Mutation in BRCA1/2, ATM, BARD1, CHEK2, FANCC, PALB2, RAD51C, RAD51D, SLX4, XRCC2 or a Homologous Recombination Deficiency

NCT05033756 is registered in ClinicalTrials.gov with Institut fuer Frauengesundheit as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase II Open-Label Study for the Comprehensive Analysis of Predictors of the Treatment With Pembrolizumab and Olaparib in Patients With Unresectable or Metastatic HER2 Negative Breast Cancer and a Deleterious Germline Mutation in BRCA1/2, ATM, BARD1, CHEK2, FANCC, PALB2, RAD51C, RAD51D, SLX4, XRCC2 or a Homologous Recombination Deficiency
Lead sponsor
Institut fuer Frauengesundheit
Phase
Phase 2
Overall status
Active, not recruiting
Start date
July 30, 2022
Completion date
February 28, 2026
Enrollment
11 (actual)
Sites
6

Conditions

As the registry lists them; a condition with its own page is linked.

breast cancer, malignant neoplasm of breast